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Case Report

Pseudohypoaldosteronism in a premature neonate with severe polyhydramnios in utero

So Yoon Ahn, Son Moon Shin, Kyung Ah Kim, Yeon Kyung Lee, Sun Young Ko

Clin Exp Pediatr. 2009;52(3):376-379. Published online March 15, 2009

We report a case of a premature newborn baby who presented with hyponatremia, hyperkalemia, and metabolic acidosis accompanied by severe polyhydramnios in utero. The baby was diagnosed with pseudohypoaldosteronism on the basis of normal 17-hydroxyprogesterone levels, elevated aldosterone, and clinical symptoms. His serum electrolyte levels were corrected with sodium chloride supplementation. Sodium supplementation was reduced gradually and discontinued at 5...

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