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Review Article

Neonatology (Perinatology)

Surfactant preparations for preterm infants with respiratory distress syndrome: past, present, and future

Ga Won Jeon

Clin Exp Pediatr. 2019;62(5):155-161. Published online February 8, 2019

Crossref 34

Following the first successful trial of surfactant replacement therapy for preterm infants with respiratory distress syndrome (RDS) by Fujiwara in 1980, several animal-derived natural surfactants and synthetic surfactants have been developed. Synthetic surfactants were designed to overcome limitations of natural surfactants such as cost, immune reactions, and infections elicited by animal proteins contained in natural surfactants. However, first-generation synthetic surfactants...

DOI: https://doi.org/10.3345/kjp.2018.07185

Original Article

Neonatology (Perinatology)

Transient intubation for surfactant administration in the treatment of respiratory distress syndrome in extremely premature infants

Ji Won Koh, Jong-Wan Kim, Young Pyo Chang

Clin Exp Pediatr. 2018;61(10):315-321. Published online September 16, 2018

Crossref 4

Purpose: To investigate the effectiveness of transient intubation for surfactant administration and extubated to nasal continuous positive pressure (INSURE) for treatment of respiratory distress syndrome (RDS) and to identify the factors associated with INSURE failure in extremely premature infants. Methods: Eighty-four infants with gestational age less than 28 weeks treated with surfactant administration for RDS for 8 years were included. Perinatal...

DOI: https://doi.org/10.3345/kjp.2018.06296

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