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Cardiology

Implication of microRNA as a potential biomarker of myocarditis

Jin-Hee Oh, Gi Beom Kim, Heeyoung Seok

Clin Exp Pediatr. 2022;65(5):230-238. Published online March 2, 2022

Web of Science 8 Crossref 7

· Myocarditis was recently examined quantitatively as inflammation of the heart muscle based on endomyocardial biopsy, and its noninvasive diagnosis remains unsatisfactory.
· Additionally, numerous miRNAs (miR-155, miR-146b, miR-590, miR-221, miR-222, etc.) coupled with inflammation or viral activation have been examined in myocarditis patients or mouse models.
· The recent identification of mmu-miR-721 (has-miR-Chr8: 96), a myocarditis-specific microRNA, demonstrated its potential as an acute myocarditis biomarker.

DOI: https://doi.org/10.3345/cep.2021.01802

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