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Review Article
Clinical presentations of critical cardiac defects in the newborn: Decision making and initial management
Jae Young Lee
Clin Exp Pediatr. 2010;53(6):669-679.   Published online June 23, 2010

The risk of mortality and morbidity of patients with congenital heart defects (CHDs) is highest during neonatal period and increases when diagnosis and proper management are delayed. Neonates with critical CHDs may present with severe cyanosis, respiratory distress, shock, or collapse, all of which are also frequent clinical presentations of various respiratory problems or sepsis in the newborn. Early diagnosis...

Original Article
Outcome and risk factors of pediatric hemato-oncology patients admitted in pediatric intensive care unit
Bo Eun Kim, Eun Ju Ha, Keun Wook Bae, Seongguk Kim, Ho Joon Im, Jong Jin Seo, Seong Jong Park
Clin Exp Pediatr. 2009;52(10):1153-1160.   Published online October 15, 2009
Purpose : To evaluate the risk factors for mortality and prognostic factors in pediatric hemato-oncology patients admitted to the pediatric intensive care unit (PICU). Methods : We retrospectively reviewed the medical records of pediatric hemato-oncology patients admitted at the PICU of the Asan Medical Center between September 2005 and July 2008. Patients admitted at the PICU for perioperative or terminal...
Case Report
A Case of Pyomyositis and Toxic Shock Syndrome Caused by Methicillin Resistant Staphylococcus aureus
Yang Kyong Kim, Dal Hyon Kim, Soon Ki Kim, Byong Kwan Son, Young Jin Hong
Clin Exp Pediatr. 2005;48(1):88-92.   Published online January 15, 2005
Pyomysitis is a primary acute bacterial infection of large skeletal muscule, usually occuring in the absence of specific cause of infection. Pyomyositis has been reported mainly in tropical countries and was rare in temperate climates. but it has been recognized with increasing frequency. Toxic shock syndrome(TSS) is an acute mutisystemic disease characterized by high fever, hypotension, multisystem dysfunction and erythematous...
Atypical Kawasaki Disease Presented with Toxic Shock Syndrome
Kyoung Yeon Lee, Jun Eun Park, Woo Sung Park
Clin Exp Pediatr. 2002;45(8):1048-1051.   Published online August 15, 2002
Toxic shock syndrome(TSS) is clinically similar to Kawasaki disease(KD) in that both of them are characterized by fever, desquamating rash and mucous membrane erythema. In contrast the main feature of TSS is hypotension, whereas the complication of KD is coronary vasculitis. We report an 8-year-old boy who fulfilled the crireria for TSS and KD. Initially he showed clinical features of...
A Case of Streptococcal Toxic Shock Like Syndrome with Pleural Effusion
Jinyoung Song, Keunha Ji, Heeseuk Kim, Jungwoo Rhoo, Dongwook Kim, Jongkook Lee
Clin Exp Pediatr. 2001;44(2):200-204.   Published online February 15, 2001
Streptococcal toxic shock like syndrome is a rapidly progressive and a fatal disease like staphylococcal toxic shock syndrome. In spite of the wide expansion and development of potent antibiotics, streptococcal infection still threatens human being. Recently we experienced a patient with toxic shock like syndrome who was suffered from fever and neck pain with rapid progression to hypotension and multiorgan...
Original Article
Hemorrhagic Shock and Encephalopathy Syndrome as a Cause of Sudden Death in Infants
Jong Won Lee, Chang Han Lee, Ki Sup Chung
Clin Exp Pediatr. 2000;43(6):814-819.   Published online June 15, 2000
Purpose : To evaluate the clinical characteristics, treatments and outcome of patients with hemorrhagic shock and encephalopathy(HSE) syndrome. Methods : We performed a clinical study on 14 patients who were diagnosed as hemorrhagic shock and having encephalopathy syndrome in the Department of Pediatrics, from 1984 to 1998. Age, sex, clinical symptoms and physical findings at admission, the most deranged laboratory findings,...
Case Report
Toxic Shock Syndrome in a 13 Year Old Boy
Ji Hye Kim, Sung Hee Oh
Clin Exp Pediatr. 1995;38(12):1706-1712.   Published online December 15, 1995
Toxic Shock Syndrome(TSS), known to be mediated by toxins produced by Staphy¡ⓒlococcus aureus, is a potentially fatal multisystemic illness unless treated properly. Although the reported cases of TSS were primarily among menstruating women, more cases of TSS among children, nonmenstruating women and male adults have been reported recently. In Korea, however, TSS has not drawn much attention yet, and no...
Original Article
Studies on Mechanism of Vascular Hyporeactivity of Mesenteric Artery from Septic Rats
Man Chul Ha, Hee Ju Park, Ki Whan Hong
Clin Exp Pediatr. 1995;38(7):922-935.   Published online July 15, 1995
Purpose : Septic shock due to gram negative bacterial infection is characterized by vasodil-ation, hypotension, and myocardial depression due to the effect of lipopolysaccharide (LPS). In spite of extensive studies, the mechanisms for the vascular effects of endotoxemia are not clear. Recently, it has been proposed that nitric oxide (NO) synthesized from L-arginine by nitric oxide synthase contributes to the...
Case Report
Two Cases of Toxic Shock Syndrome (TSS) in Infants
Jin Kil Park, Hong Ju Choi, Hee Tag Im, Jae Sam Kim, Hyo Kyung Shin, Chul Ho Koo
Clin Exp Pediatr. 1994;37(6):861-871.   Published online June 15, 1994
Much has been learned of the pathogenesis and pathophysiology of the toxic shock syndrome (TSS) sinde the initial description in 1978 by Dr. James K, Todd. The clinical illness in defined by the criteria listed in the case definition formulated for epidemiologic studies. With the advent of widespread recognition of TSS, there have been numerous published reports describing the clinical...