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Original Article
Quantification of endothelin-1 in human umbilical venous endothelial cell culture supernatants of small for gestational age and preeclampsia neonates
Won Kyoung Cho, So Young Kim, Chung Sik Chun
Clin Exp Pediatr. 2007;50(12):1194-1199.   Published online December 15, 2007
Purpose : It was generally accepted now a days that the pathogenesis of preeclampsia, small for gestational age (SGA), intrauterine growth retardation and fetal origin of adult diseases were related with a endothelial cell dysfunction. The purpose of this study was to know the relation of such diseases by assessing the level of endothelin-1. Methods : SGA babies, newborns of...
The Effects of Intravenous Immunoglobulin(IVIG) and Methylprednisolone on the mRNAs Expressions of VEGF, VCAM-1 and IL-1β of Human Umbilical Vein Endothelial Cells(HUVEC) Stimulated by IL-1β
Soh Yeon Kim, Sun Jeong Lim, Ji Whan Han, Kyung Yil Lee, Joon Sung Lee
Clin Exp Pediatr. 2004;47(12):1325-1333.   Published online December 15, 2004
Purpose : Kawasaki disease(KD) manifests a systemic vasculitis of unknown etiology in young children. Vascular endothelial growth factor(VEGF), vascular cell adhesion molecule-1(VCAM-1) and interleukin-1 beta(IL-1β) may play important roles in the pathogenesis of KD. Intravenous immunoglobulin(IVIG) and methylprednisolone(MP) are therapeutically effective for KD, however, the precise mechanisms of the two drugs are still unknown. We investigated the therapeutic efficacy of...
Repetition of Apoptosis Induced by Amiloride Derivatives in Human Umbilical Vein Endothelial Cells
Kyu Chang Park, Kyu Sang Park, Soo Jee Moon
Clin Exp Pediatr. 2003;46(1):56-66.   Published online January 15, 2003
Purpose : Human umbilical vein endothelial cells(HUVECs) play an important role in regulating blood flow by releasing vasoactive substances. It has been reported that endothelial impairment and dysfunction might be a primary cause of placental vascular disease, which is manifested clinically as preeclampsia in mother and intrauterine growth restriction in fetus. Furthermore, the frequency of apoptotic changes is increased in...
Balloon atrial septostomy through umbilical vein approach using flexible guide wire and sheath technique.
In Sook Park, Ki Soo Kim, Chang Yee Hong, Shi Joon Yoo
Clin Exp Pediatr. 1991;34(9):1294-1298.   Published online September 30, 1991
Balloon atrial septostomy is accepted as the best initial palliative treatment in infants with certain types of cyanotic congenital heart disease and the importance of prompt creation of atrial communi- cation can not be overemphasized in these patients. Balloon atrial septostomy is performed through femoral vein using percutaneous technique in most cases and is rarely done by cut down approach. However, percutaneous femoral vein...