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Henoch-Schöenlein purpura, also known as anaphylactoid purpura, is characterized by palpable
purpura, colicky abdominal pain, gastrointestinal hemorrhage, arthralgias, and renal involvement.
Histopathologically, the condition represents a vasculitis, and in fact, it may be the most common
vasculitis syndrome affecting children. The pathogenesis of Henoch-Schöenlein purpura remains
poorly understood, but it is postulated that an unknown antigenic stimulus causes elevation of
circulating IgA and that complement... |