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Review Article

Nephrology (Genitourinary)

Renal replacement therapy in neonates with an inborn error of metabolism

Heeyeon Cho

Clin Exp Pediatr. 2019;62(2):43-47. Published online November 7, 2018

Crossref 11

Hyperammonemia can be caused by several genetic inborn errors of metabolism including urea cycle defects, organic acidemias, fatty acid oxidation defects, and certain disorders of amino acid metabolism. High levels of ammonia are extremely neurotoxic, leading to astrocyte swelling, brain edema, coma, severe disability, and even death. Thus, emergency treatment for hyperammonemia must be initiated before a precise diagnosis is...

DOI: https://doi.org/10.3345/kjp.2018.07143

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