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Original Article

Serum metabolomic profile in children with sepsis-associated acute kidney injury

Nisha Chaudhary, Praveen Singh, Abhijeet Saha, Shantanu Sengupta

Background: Sepsis-associated acute kidney injury (SA-AKI) contributes to high morbidity and mortality rates in children; however, current diagnostic tools (serum creatinine and urine output) lack sensitivity for early detection. Metabolomics can be used to discover novel metabolic markers to enable early diagnosis and prognosis and provide therapeutic targets for SA-AKI.
Purpose: This study was aimed to identify the differentially expressed serum...

DOI: https://doi.org/10.3345/cep.2025.02439 [Accepted]

Clinical Note

Nephrology (Genitourinary)

First episode of nephrotic syndrome with acute abdominal pain

Samridhi Goyal, Rachita Singh Dhull, Bobbity Deepthi, Abhijeet Saha

Clin Exp Pediatr. 2020;63(10):411-414. Published online July 21, 2020

Question: What are the likely causes of pain abdomen in Nephrotic syndrome?
Finding: Severe hypovolemia leading to mesenteric ischemia, spontaneous bacterial peritonitis, gastroenteritis, adverse effect of corticosteroids leading to gastritis, mesenteric ischemia due to thromboembolism, acute appendicitis, intussusception due to severe gut wall oedema and rarely Psoas abscess.
Meaning: Clinical suspicion and careful investigation is warranted to diagnose rare cause of pain abdomen like Psoas abscess.

DOI: https://doi.org/10.3345/cep.2019.01333

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