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A Case of Hereditary C7 Deficiency Associated with Meningococcal Meningitis

Hyun Woo We, Won Duck Kim, Sun Ju Lee, Dong Seok Lee, Doo Kwun Kim, Sung Min Choi, Gyoung Yim Ha

Clin Exp Pediatr. 2004;47(7):799-802. Published online July 15, 2004

The complement system is composed of more than 25 different proteins and is usually divided into classical and alternative pathways. Complement component 7(C7) is one of the five terminal complement proteins that, upon activation of either the classical or the alternative pathway, interacts sequentially to form a large protein-protein complex, called membrane attack complex(MAC). Assembly of the MAC on target...

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