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Original Article
Iron chelating agent, deferoxamine, induced apoptosis in Saos-2 osteosarcoma cancer cells
Eun Hye Park, Hyo Jung Lee, Soo Yeon Lee, Sun Young Kim, Ho Keun Yi, Dae Yeol Lee, Pyoung Han Hwang
Clin Exp Pediatr. 2009;52(2):213-219.   Published online February 15, 2009
Purpose : Iron is a critical nutritional element that is essential for a variety of important biological processes, including cell growth and differentiation, electron transfer reactions, and oxygen transport, activation, and detoxification. Iron is also required for neoplastic cell growth due to its catalytic effects on the formation of hydroxyl radicals, suppression of host defense cell activities, and promotion of...
Alteration of Growth Factor Expression after Acute Ischemic Renal Injury
Yang Sim Koe, Soo Yeon Lee, Won Kim, Soo Chul Cho, Pyoung Han Hwang, Jung Soo Kim, Dae-Yeol Lee
Clin Exp Pediatr. 2003;46(7):687-694.   Published online July 15, 2003
Purpose : Regeneration and repair after ischemic renal injury appears to be modulated by circulating or locally produced growth factors. This study examined the changes of serum insulin like growth factor(IGF-I) and renal expression of IGF-I and II, vascular endothelial growth factor(VEGF), transforming growth factor-β(TGF-β), and connective tissue growth factor(CTGF) during the active regeneration period after acute ischemic injury. Methods :...
Case Report
A Case of Cerebral Vasculitis in Henoch-Shonlein Purpura
Soo Yeon Lee, Ju Mi Choung, Dong Jin Hwang, So Hee Eun, Pyoung Han Hwang
Clin Exp Pediatr. 2002;45(12):1601-1605.   Published online December 15, 2002
Henoch-Sh nlein Purpura(HSP) is an immuologically mediated systemic vasculitis of small blood vessels affecting predominantly the skin, gastrointestinal tract, joints, and kidneys. Clinical neurological manifestations such as headaches, behavioral changes, mental changes, seizures, and visual loss are described, but neurological complication are rare during the course of HSP. We experienced a case of an 8 year-old male with HSP who...