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Original Article
Neurology
Efficacy and tolerability of adjunctive perampanel treatment in children under 12 years of age with refractory epilepsy
Yuni Yun, Dongsub Kim, Yun-Jeong Lee, Soonhak Kwon, Su-Kyeong Hwang
Clin Exp Pediatr. 2019;62(7):269-273.   Published online December 26, 2018

Purpose: There is limited data on the use of perampanel in children under 12 years of age. We evaluated the efficacy and tolerability of adjunctive perampanel treatment in children under 12 years of age with refractory epilepsy. Methods: This retrospective observational study was performed in Kyungpook National University Hospital from July 2016 to March 2018. A responder was defined as a...
Clinical importance of F-waves as a prognostic factor in Guillain-Barré syndrome in children
Eung-Bin Lee, Yun Young Lee, Jae Min Lee, Su Min Son, Su-Kyeong Hwang, Soonhak Kwon, Sae Yoon Kim
Clin Exp Pediatr. 2016;59(6):271-275.   Published online June 30, 2016
Purpose

A limited number of studies have examined the link between F-wave abnormalities and clinical presentation in pediatric Guillain-Barré syndrome (GBS). Therefore, this study examined the importance of F-wave abnormalities as a prognostic factor in pediatric GBS patients.

Methods

The records and electrodiagnostic studies (EDS) of 70 GBS patients were retrospectively evaluated, and divided into 2 groups according to the results of EDS....

Review Article
Early-onset epileptic encephalopathies and the diagnostic approach to underlying causes
Su-Kyeong Hwang, Soonhak Kwon
Clin Exp Pediatr. 2015;58(11):407-414.   Published online November 22, 2015

Early-onset epileptic encephalopathies are one of the most severe early onset epilepsies that can lead to progressive psychomotor impairment. These syndromes result from identifiable primary causes, such as structural, neurodegenerative, metabolic, or genetic defects, and an increasing number of novel genetic causes continue to be uncovered. A typical diagnostic approach includes documentation of anamnesis, determination of seizure semiology, electroencephalography, and...

Original Article
Prevalence of restless legs syndrome and sleep problems in Korean children and adolescents with attention deficit hyperactivity disorder: a single institution study
Soonhak Kwon, Youngsoo Sohn, Seong-Hoon Jeong, Un-Sun Chung, Hyeeun Seo
Clin Exp Pediatr. 2014;57(7):317-322.   Published online July 23, 2014
Purpose

Attention deficit hyperactivity disorder (ADHD) is a common disorder in school-aged children. Patients with restless legs syndrome (RLS) often present with ADHD symptoms and vice versa. This study was the first to attempt to identify the prevalence of RLS and sleep problems in children with ADHD in Korea.

Methods

Patients diagnosed with ADHD were asked to complete a sleep questionnaire. The sleep...

Cognitive and other neuropsychological profiles in children with newly diagnosed benign rolandic epilepsy
Soonhak Kwon, Hye-Eun Seo, Su Kyeong Hwang
Clin Exp Pediatr. 2012;55(10):383-387.   Published online October 29, 2012
Purpose

Although benign rolandic epilepsy (BRE) is a benign condition, it may be associated with a spectrum of behavioral, psychiatric, and cognitive disorders. This study aimed to assess the cognitive and other neuropsychological profiles of children with BRE.

Methods

In total, 23 children with BRE were consecutively recruited. All children underwent sleep electroencephalography (EEG) and were assessed on a battery of comprehensive neuropsychological...

Clinical experience with amitriptyline for management of children with cyclic vomiting syndrome
Ye Jee Shim, Jung-mi Kim, Soonhak Kwon, Byung-Ho Choe
Clin Exp Pediatr. 2009;52(5):538-543.   Published online May 15, 2009
Purpose : To report the clinical experience with amitriptyline for managing children with cyclic vomiting syndrome (CVS). Methods : Totally, eleven children (eight males) were diagnosed with CVS. Of these, medical records were reviewed for eight children treated with amitriptyline; three children were not treated because one was not followed up and two were kept under observation to study the...
Clinical Lecture
Neurological Examination after the Newborn Period until 3 Years of Age
Soonhak Kwon
Clin Exp Pediatr. 2004;47(11):1142-1148.   Published online November 15, 2004
The children should not be regarded as miniature adults since they are in the dynamic process of growth and development. Among many pediatric problems, the developmental delay may be central to them. For this reason, primary care physicians, especially pediatricians should be able to manage children with probable developmental delays because early detection and treatment of developmental delay or neurological...
Case Report
A Case of Ornithine Transcarbamylase(OTC) Deficiency
Soonhak Kwon, Yejhin Lee, Byung-Ho Choe, Sangkwon Lee
Clin Exp Pediatr. 2000;43(1):123-127.   Published online January 15, 2000
OTC deficiency is an X-linked disorder in which the synthesis of urea is impaired. OTC catalyzes the synthesis of citrulline from carbamyl phosphate and ornithine. Complete or partial deficiencies of this enzyme may lead to Reye syndrome like picture such as encephalopathy, hepatic dysfunction, hyperammonemia, etc. We recently had a case that was presented as recurrent Reye syndrome, and was...