• Search
  • Advanced Search

Search

  • HOME
  • Search
Original Article
Possible Neuroprotective Role of Exogenous Growth Hormone on Hypoxic-Ischemic Brain Injury in Neonatal Rats
Young Pyo Chang, Mi Kyung Jung, Youn Hee Jee, Jae Ju Cho, Soon Bum Lee, Woo Sung Park, Jong-Wan Kim, Dong Hoon Shin
Clin Exp Pediatr. 2004;47(11):1210-1215.   Published online November 15, 2004
Purpose : This study was performed to evaluate the possible neuroprotective effect of exogenous growth hormone on hypoxic-ischemic brain injury in neonatal rats. Methods : After ligation of the right common carotid artery, seven-day old Sprague-Dawley rats(n= 75) were exposed to 8% oxygen for two hours. In a growth hormone(GH)-treated group(n=25), each animal was subcutanously injected by GH(50 mg/kg, Grotrpin ,...
Effect of Hypoxia-Ischemia on Striatal Monoamine Metabolism in Neonatal Rat Brains
Youn Hee Jee, Hyung Gun Kim, Woo Sung Park, Young Pyo Chang
Clin Exp Pediatr. 2003;46(8):789-794.   Published online August 15, 2003
Purpose : We intended to evaluate the effect of hypoxia-ischemia on extracellular striatal monoamine metabolism in neonatal rat brains by in vivo microdialysis. Methods : The right common carotid arteries of five or six-day old rats were surgically ligated, and the probes for microdialysis were inserted into the right striatum with stereotaxic instrument. After stabilization for two hours, artificial cerebrospinal fluid...