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Original Article
Growth and Neurodevelopmental Outcome at 15 Months of Corrected Age in Very Low Birth Weight Infants with Chronic Lung Disease
Seon Young Kim, Chang Yee Cho, Young Youn Choi
Clin Exp Pediatr. 2001;44(10):1112-1118.   Published online October 15, 2001
Purpose : This study was performed to compare the growth and neurodevelopmental outcome at 15 months of corrected age in very-low-birth weight infants between chronic lung disease(CLD) group and the control group. Methods : Very-low-birth-weight infants who were admitted and survived in the NICU(neonatal intensive care units) of Chonnam Univeristy Hospital from Jan. 1997 to Jan. 2000 were divided into...
Case Report
A Case of Chronic Pneumonitis of Infancy in Pediatric Interstitial Lung Disease
Hyun Oh Jang, Se Chang Ham, Young Kyoun Kim, Se Wook Oh, Yong Won Park
Clin Exp Pediatr. 2001;44(9):1085-1090.   Published online September 15, 2001
The interstitial lung diseases(ILD) comprises a large, heterogeneous group of disorders characterized by derangement of alveolar walls and alveolar capillary unit causing restrictive pulmonary dysfunction and disordered gas exchange. It is rare, especially in children, and the opinions on investigation and treatments are controversial. The classification of adult ILD is applied to that of children. But considering occurrence during the developing state of lung...
Original Article
A Study on the Effect of the Combined Use of Gentle Ventilation and High-Frequency Ventilation on the Incidence of Chronic Lung Disease
Ji Yeon Baek, Jae Han Kim, Kyung Ae Park, Suk Ho Kang, Man Hoe Hur, Sang Geel Lee
Clin Exp Pediatr. 2000;43(12):1544-1551.   Published online December 15, 2000
Purpose : This study was conducted to determine the correlation between the incidence of chronic lung disease and the combined use of gentle ventilation and high-frequency ventilation. Methods : The subject group consisted of 63 very low birthweight infants of less than 1500gm who were born and survived through ventilator treatment in the Fatima neonatal intensive care unit for four...
Clinical Trial of Domestically Developed Bovine Lung Surfactant YY-38 in Neonatal Respiratory Distress Syndrome
Chul Lee, Jeong Nyun Kim, Min-Soo Park, Moon Sung Park, Shin Won Yoon, Wook Chang, Ran Namgung, Kook In Park, Dong-Gwan Han
Clin Exp Pediatr. 1999;42(4):472-483.   Published online April 15, 1999
Purpose : We previously reported modified bovine lung surfactant YY-38(NewfactanⓇ) had a low surface tension, good hysteresis, and exhibited good pressure-volume curve in animal experiment (J Korean Pediatr Asso 1997;40:771-85). We performed multicenter clinical trial of NewfactanⓇ in neonatal RDS. Methods : Seventy-seven infants with RDS(GA 31.8¡¾2.9 wks and BW 1,809¡¾592 gm) in 4 NICU were enrolled. After administration of...
Clinical Characteristics of Long-Standing Foreign Body in Airway
Jin Hwa Jeong, Seon Mi Jin, Yun Ae Jeon, Ki Woong Sung, Young Yull Koh
Clin Exp Pediatr. 1999;42(2):186-194.   Published online February 15, 1999
Purpose : Although the diagnosis of foreign bodies in the airway can be made early, retained and neglected foreign bodies are a common occurrence. The objective of this study was to characterize the clinical features of children diagnosed beyond 14 days following inhalation of a foreign body, long-standing foreign body in airway(LFB). Methods : We reviewed the records of 180 cases...
The Assessment of Pulmonary Parenchymal Damage in Congenital Heart Disease using Lung Perfusion Scan
Hong Ryang Gil, Jae Goo Lee, Kang Uk Lee, Eun Ho Yi, Myung Ja Yun, Chung Il Noh, Jung Yeon Choi, Yong Soo Yun
Clin Exp Pediatr. 1998;41(5):640-645.   Published online May 15, 1998
Purpose : In acyanotic congenital heart disease of children with left to right shunt, 99mTc- Macroaggregate albumin(MAA) was employed to determine the scintigraphic severity of pulmonary parenchymal damage. Methods : These data of lung perfusion scan using 99mTc-MAA were compared with hemodynamic values obtained from cardiac catheterization. Results : The mean Pulmonary arterial pressure(≥30mmHg), total pulmonary resistance(≥2 Wood unit)...
Clinical Study and Diagnostic Value of the Lung Perfusion Scan in Foreign Body Aspiration
Gyo-Dang Koo, Young-Ho Rah, Chong-Woo Bae, Sa-Jun Chung, Yong-Mook Choi
Clin Exp Pediatr. 1998;41(1):74-80.   Published online January 15, 1998
Purpose : Early diagnosis of foreign body aspiration and removal of the inhaled material may save the patient from chronic illness and may prevent serious complications. At present the diagnostic problems of bronchial foreign bodies are being solved by using the lung scanning technique. Therefore, we investigated the clinical study and diagnositic value of the lung perfusion scan in foreign body aspiration. Methods : Eighteen...
Physical and Biological Activity of Domestic Product of Modified Bovine Lung Surfactant
Chul Lee, Min Soo Park, Moon Sung Park, Jung Nyeon Kim, Jong Wook Lee, Kwang Hyun You, Won Jae Kwag, Kook In Park, Ran Nam gung, Dong Gwan Han
Clin Exp Pediatr. 1997;40(6):771-785.   Published online June 15, 1997
Purpose : Neonatal respiratory distress syndrome is caused by the deficiency of lung surfactant in premature babies. For the treatment of RDS at present surfactants such as Surfacten․ (Tokyo-Tanabe Co., Japan) and Exosurf․ (Wellcome Co., USA) are used. As awarded the grant from the Ministry of Science and Technology for a model research project of Medium-Technology program, we have modified (supplemented) the bovine lung...
Genital Mycoplasmasin the Newborn Infants: Colonization, Prevalence and Clinical Significance
Yun Sil Chang, Sung Gwon Kim, Beyong Il Kim, Won Soon Park, Bo Hyun Yoon, Eui Chong Kim, Jung-Hwan Choi, Chong Ku Yun
Clin Exp Pediatr. 1996;39(8):1084-1094.   Published online August 15, 1996
Purpose : The genital mycoplasmas: Ureaplasma urealyticum and Mycoplasma hominis have recently assumed an increasing importance as neonatal pathogens especially in preterm infants. The aim of the present study was to determine the prevalence of infections with these organisms in newborn infants who were admitted in Neonatal Intensive Care Unit(NICU) and who were suspected having infection in newborn nursery Methods : Sixty four inborns who...
Case Report
A Case of Agenesis of the Right Lung Accompanied by Cleft Lip
Dong Joon Lee, Moon Soo Han, Won Bae Lee, Joon Sung Lee
Clin Exp Pediatr. 1995;38(2):252-256.   Published online February 15, 1995
This paper describes a case of agenesis of the right lung in a male neonate, who suffered respiratory difficulty. He was evaluated by plain X-ray, bronchography, lung perfusion scan, chest CT, and brain CT. After he died, autopsy was performed. The results revealed multiple anomalies which included cleft lip and palate, absence of left thumb and radius bone, hemivertebra between L1...
Five Cases of Thymic Hyperplasia
Soo Kyoung Lee, Soo Young Lee, Kyu Eun Kim, Byung Ju Chung, Ki Young Lee
Clin Exp Pediatr. 1992;35(10):1435-1442.   Published online October 15, 1992
Diagnosis of thymic hyperplasia may be quite difficult because thymus has not always sail appearance and it sometimes appears to be a huge mass in the mediastinum. This fact causes sometimes diagnostic thoracotomy or often make primary physicians fail in treatment and transfer their patients to other hospitals. But in most cases diagnosis can be made by a lateral chest...
A Case of Agenesis of the Right Lung with H-type Tracheoesophageal Fistula
Yong Seok Choi, Kyung Hee Kim, Young Chul Ahn, Baik Lin Eun, Kwang Je Beck
Clin Exp Pediatr. 1992;35(6):816-821.   Published online June 15, 1992
Agenesis of the lung is a developmental defect with complete absence or profound hypoplasia of one or both lung : absence of one lung is more common. Absence of both lung is very rare and is incompatible with life. Unilateral or bilateral agenesis of the lung often associated with the skeletal, cardiovascular, gastrointestinal and genitourinary anomalies. H-type tracheoesophageal fistula in...
A Case of Right Lung Agenesis
Seung Hyun Seo, Yu Sub Shin, Ki Sik Min, Jong Wan Kim, Kwang Nam Kim, Ki Yang Ryoo
Clin Exp Pediatr. 1992;35(3):428-433.   Published online March 15, 1992
Lung agenesis is the very rare disease which is defined as total absence of the pulmonary parenchyma, its vascular supporting structure, and bronchi beyond the carina. In many cases, there are coexisting anomalies involving the skeletal, cardiovascular, gastrointestinal, and genitourinary systems. Also, severe respiratory infections are common in infancy and may lead to pneumonia and death. When associated anomalies are...
A Case of Agenesis of the Right Lung
Hyun Soon Lee, Gyeong Cheol Yoon, Se Wook Oh, Ho Seek Ahn, Sung Won Kim, Chung Hee Chi
Clin Exp Pediatr. 1992;35(2):240-244.   Published online February 15, 1992
Unilateral lung agenesis is defined with absence of parenchyme, supporting structures and airway below the level of the carina. Lung agenesis is associated with other anomaly of cardiovascular system, musculoskeletal system and genitourinary system in about 50% cases. In most cases, the diseases is found due to respiratoru problems. Prognosis is variable but largely depends on the associated anomaly and...
Original Article
Congenital cystic diseases of the lung.
Won Soon Park, Young Pyo Chang, Hee Ju Kim, Young Yull Koh, Jung Hwan Choi, Chong Ku Yun, Joo Hyun Kim
Clin Exp Pediatr. 1991;34(12):1671-1677.   Published online December 31, 1991
Congenital cystic diseases of the lung (CCDL) is a clinical group of disorders characterized by a cystic appearance of pulmonary tissue. It can be classified into four distinct categories: 1) Congenital lobar emphysema (CLE), 2) Congenital cystic adenomatoid malformation (CCAM), 3) Pulmonary sequeestration (PS), and ^Bronchogenic cyst (BC). 24 patients with CCDL admitted to the Seoul National University Children’s Hospital from January 1984 to June...
A Case of Right Lung Agenesis Associated with Right Hemifacial Atrophy.
Jung Tak Kim, Young Mi Chung, Dong Goo Lee, Byeong Ju Jeoung, Kyu Earn Kim, Ki Young Lee, Jin Suk Suh
Clin Exp Pediatr. 1990;33(12):1723-1728.   Published online December 31, 1990
Unilateral lung agenesis is a rare disease with associated anomalies of soft tissue, the musculos- keletal system, cardiovascular system and gastrointestinal system in 50-60% of cases. When associat- ed anomalies are absent, the disease may not be discovered during a lifetime, but in most of the cases, frequent respiratory infection or associated anomalies make it possible for diagnosis of the disease. Since early diagnosis...
A case of Asphyxiating Thoracic Dystrophy.
Hyung Goo Cho, Hwang Min Kim, Jae Seung Yang, Jong Soo Kim, Whi Yul Cho, So Young Jin
Clin Exp Pediatr. 1990;33(9):1294-1300.   Published online September 30, 1990
Asphyxiating thoracic dystrophy, a rare form of bony dysplasia, is characterized by extreme constriction of thorax, short limbed dwarfism, abnormalities of pelvic bone in neonatal period, and progressive interstitial nephritis in childhood. The incidence of this syndrome has been estimated at 1 per 100,000 to 130,000 live births and more than 100 patients have been reported worldwide. Infants with asphyxiating thoracic dystrophy usually have...
A Case of Adrenal Cortical Carcinoma.
Ho Won Kang, Hong Ja Kang, Hong Bae Kim, Ji Sub Oh
Clin Exp Pediatr. 1990;33(8):1159-1165.   Published online August 31, 1990
This is a case report of adrenal cortical carcinoma in a 2 year 7 month old male patient who was diagnosed by clinical features, endocrinologic studies, radiologic studies and pathologic examina- tions. Cushing syndrome and virilization caused by adrenal cortical carcinoma were found. Left total adrenalectomy was performed. No evidence of metastasis was found at the time of operation. 3 months later, lung metastases...
A Case of Congenital Cystic Adenomatoid Malformation (Type1) of the Lung.
Dong Sik Kim, Hwang Min Kim, Jae Seung Yang, Baek Keun Kim, Jong Soo Kim, Dong Hwan Shin
Clin Exp Pediatr. 1990;33(6):830-834.   Published online June 30, 1990
A rare form of congenital cystic lung disease, characterized by the presence of one or usually multiple interconnecting cyst, is called congenital cystic adenomatoid malformation of the lung. This disease almost invariably presents either in live premature or stillborn infants, and death in those infants bom alive usually occurs within a few hours of birth. Infants with congenital cystic adenomatoid malformation usually have tachypnea,...
A Case of Congenital Cysitic Adenomatoid Malformation of Lung.
Youe Kawn Kim, Deuk Hwan Jun, Bae Young Kim, Won Il Park, Kyung Ja Lee
Clin Exp Pediatr. 1990;33(2):225-228.   Published online February 28, 1990
Congenital cystic adenomatoid malformation is a rare variant of pulmonary cystic disease char- acterized by a mass of cysts lined by proliferating bronchial or cuboidal epithelium. The onset of symptoms, which are cyanosis, and tachypnea, usually occurs during the first week of life. We have experienced a case of congenital cystic adenomatoid malformation in a 9 month-old female. The diagnosis was mady by chest...
Two Cases of Chronic Bronchitis in Children Who Showed Perfusion Defects at the Base of Lung.
Hyeon Soo Lee, Kyu Earn Kim, Ki Young Lee
Clin Exp Pediatr. 1988;31(12):1663-1668.   Published online December 31, 1988
We experienced two cases of chronic bronchitis in 9 4/12 year female & 10 year old male who were admitted at department of Pediatrics, College of Medicine, Yonsei University. In which all laboratory findings including chest X-ray were normal, but on the scitiscan perfusion defects were noted at the base of lung and clinically improved accociated with disappearance of perfusion defects ossurred after treatment. The...
Diagnostic Value of the Lung Perfusion Scan in Foreign body Aspiration.
Ki Hong Park, Chong Woo Bae, Byoung Soo Cho, Sa Joon Chung, Yong Mook Choi, Chang Il Ahn, Sun Wha Lee, Chang Il Cha
Clin Exp Pediatr. 1988;31(10):1301-1307.   Published online October 31, 1988
Lung perfusion scan was performed on 5 young children suspected as foreign body aspiration who had been admitted on the Department of Pediatrics, Kyung Hee University Hospital from May 1986 to January 1988. The results were as follows: 1) All children had been showed perfusion defect as compatible as acute obstructive lung disease by lung perfusion scan and foreign bodies in bronchial tree were proved on...
A Role of Electrolytes in Fetal Tracheal Fluids As a Fetal Lung Maturity Profile.
Dong Hak Shin, Sung Do Yoon
Clin Exp Pediatr. 1988;31(10):1267-1274.   Published online October 31, 1988
The Fetal lung is filled by fluid from the beginning of the canalicular stage until the completion of fetal development. The fluid is produced by the lungs and flows out of the traches: Part of it is swallowed & part enters the amniotic fluid. The fluid is differs in composition from the plasma & amniotic fluid. Ifs electrolytes components change very little during...
Diagnostic Value of Perfusion Lung Scan on Airway Foreign Body in Children.
Ki Young Lee, Kyu Earn Kim
Clin Exp Pediatr. 1988;31(6):715-722.   Published online June 30, 1988
The authors evaluated diagnostic value of perfusion scan of the lung in the children who had foreign bodies. Perfusion lung scan with 99mTc MAA was performed in 23 cases of children with foreign bodies in the airway. The results of study were as follows; 1) The majority of 23 cases with foreign body in airway was infants and young children, and 19 cases (82.6%) of them was...
A Case of Idiopathic Unilateral Hyperlucent Lung Associated with Low Serum IgA.
D H Chee, W S Shim, M I Lee, D H Ahn, K C Sohn, J H Yoon
Clin Exp Pediatr. 1988;31(4):526-531.   Published online April 30, 1988
Swyer-James syndrome is a radiological entity that consists primarily of an abnormal radiolucency of one lung or lobe due to obliterative bronchiolitis with air entrapment. We report a case of idiopathic unilateral hyperlucent lung which was confirmed by chest roentgenography, bronchogra- phy and pulmonary arteriography in a patient whose serum IgA was significantly lowered.
A Case of Pulmonary Paragonimiasis Whose Parenchymal Lesions Dtected by Tomogram and Perfusion Scan of the Lung.
Jung Keun KIm, Kyu Earn Kim, Ki Young Lee
Clin Exp Pediatr. 1988;31(4):519-525.   Published online April 30, 1988
Recently, we experienced a case of pulmonary paragonimiasis in a 8 year old boy with a chief complaint of intractable pleural fluid for one year. The cystic cavity was detected by tomogram, but not by chest X-ray and apparant regional pulmonary perfusion defect was also detected at the same site of that lesion by lung scan. We report this case with brief review of...
A Case of Potter Syndrome with Bilateral Polycystic Kidneys.
Chun Hwa Lee, Jung Hwan Choi, Yong Choi, Chong Ku Yun, Yeon Lim Suh, Je G Chi, Son Moon Shin
Clin Exp Pediatr. 1987;30(11):1282-1286.   Published online November 30, 1987
In 1946, Potter described a series of 20 cases of infants in whom bilateral absence of the kidneys was associated with hypoplasia of the lungs and characteristic faces. Afterwards it has been known that any condition that causes significant reduction in urine formation or excretion will result in oligohydramnios accounts for many of the nonrenal features of Potter syndorme. We report a case...
Case Report
A Case of Potter Syndrome Type I.
Jong Cheol Ryu, Jae Kwang Hong, Jun Taek Park, Jung Sik Min, Chang Jee Choi, Je Geun Chi
Clin Exp Pediatr. 1986;29(10):1152-1156.   Published online October 31, 1986
We have experienced a case of Potter syndrome type I in a newborn infant who presented with severe respiratory distress soon after birth. The diagnosis was made with autopsy findings consisted of bilateral polycystic renal dysplasia, bilateral hypoplastic lung , facies renalis, fibrocystic change of liver, patent ductus arteriosus, patent foramen ovale, ureter and urinary bladder hypoplasia and calcaneovarus. Brief...
A Case of Primary Lung Cancer(Squamous cell ca.) in Children.
Soo Ryun Choi, Choong Hyun Kim, Soon Ok Byun, Ji Sub Oh, Sung Kyun Im, Ok Ji Park
Clin Exp Pediatr. 1985;28(12):1256-1260.   Published online December 31, 1985
We have experienced a case of primary lung cancer (squamous cell ca.) in a 15 years-old boy who presented with productive coughing and mild fever. The diagnosis was made through thoracic roentgenogram, thoracotomy, and biopsy. A brief review of the related literature is given.
Original Article
A Clinical Study of Wet Lung Disease.
Soon Wook Lim, Jae Seung Yang, Chul Lee, Dong Gwan Han, Chin Suck Suh
Clin Exp Pediatr. 1985;28(9):852-860.   Published online September 30, 1985
The authors studied 36 cases of wet lung disease who were born and admitted to pediatric department of Severance hospital from January 1981 to June 1984. following results were obtained: 1)The incidence of wet lung disease was 0.5% and the predisposing factors were male sex(78%), full term(75%), C-section(58%) and multipara(72%). 2)Number of cases whose Apgar score were above 7 werp...