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Review Article
A suggestion of health insurance for children
Baik-Lin Eun
Clin Exp Pediatr. 2008;51(4):339-342.   Published online April 15, 2008
The Korean Health Insurance (KHI) has been introduced since 1977 and it took only 12 years that KHI had accomplished the total coverage of Korean population. The remarkable success of KHI can be compared with other OECD countries which had taken some 30 years to over 100 years to establish the total coverage of the population. Life expectancy at birth...
Overview of the national health screening program for infant and children
Baik-Lin Eun, Seong Woo Kim, Young Key Kim, Jung Wook Kim, Jin Soo Moon, Su Kyung Park, In Kyung Sung, Son Moon Shin, Sun Mi Yoo, So Hee Eun, Hea Kyoung Lee, Hyun Taek Lim, Hee Jung Chung
Clin Exp Pediatr. 2008;51(3):225-232.   Published online March 15, 2008
The mission of National Health Screening Program for Infant and Children is to promote and improve the health, education, and well-being of infants, children, families, and communities. Although the term 'diagnosis' usually relates to pathology, a similar diagnostic approach applies to the child seen primarily for health supervision. In the case of health, diagnosis determines the selection of appropriate health...
Clinical aspects of injury and acute poisoning in Korean pediatric patients
Joon Seok Park, Mi Jin Lee
Clin Exp Pediatr. 2008;51(2):116-121.   Published online February 15, 2008
Unintentional injuries are the most important cause of morbidity and mortality in the pediatric population, and the home is the most common site of injury for children in Korea. The most common cause of injury was slip down. Fall down and burn were frequent in infant/toddlers group, automobile and bicycle accident more frequent in preschool children. Findings from the survey...
2007 Korean National Growth Charts: review of developmental process and an outlook
Jin Soo Moon, Soon Young Lee, Chung Mo Nam, Joong-Myung Choi, Bong-Keun Choe, Jeong-Wan Seo, Kyungwon Oh, Myoung-Jin Jang, Seung-Sik Hwang, Myung Hwan Yoo, Young Taek Kim, Chong Guk Lee
Clin Exp Pediatr. 2008;51(1):1-25.   Published online January 15, 2008
Purpose : Since 1967, The Korean Pediatric Society and Korean Government have developed Korean Growth Standards every 10 years. Last version was published in 1998. During past 40 years, Korean Growth Standards were mainly descriptive charts without any systematic nor statistical standardization. With the global epidemic of obesity, many authorities such as World Health Organization (WHO) and United States' Centers...
Original Article
Birth weight for gestational age patterns by sex, plurality, and parity in Korean population
Jung Ju Lee
Clin Exp Pediatr. 2007;50(8):732-739.   Published online August 15, 2007
Purpose : A universal standard of the birth weight for gestational age cannot be made since birth weight distribution varies with races, nations and eras. This report aims to establish the birth weight for gestational age patterns by sex, plurality, and parity, specific for Korean live births. Methods : The national birth certificate data of all live births in Korea from...
Case Report
A case of hereditary pancreatitis with a N29I mutation in the cationic trypsinogen gene
Jee Youn Shin, Dae Sung Oh, Jeong Min Rheu, Jeong Ok Shim, Ji Sook Park, Jae Sung Ko, Jeong Kee Seo
Clin Exp Pediatr. 2006;49(10):1111-1115.   Published online October 15, 2006
Hereditary pancreatitis is an autosomal dominant disease characterized by recurrent episodes of pancreatitis, often beginning in childhood, with a positive family history involving at least two other affected family members with no known other precipitating factors. Most forms of hereditary pancreatitis are caused by one of two common mutations, i.e., R122H in exon 3 and N29I in exon 2 of...
Original Article
Human metapneumovirus infection in Korean children
Hee-Hyun Yeom, Joon-Soo Park, Dong-Jun Jeong, Chang-Jin Kim, Yong-Bae Kim, Dea-Hoon Lee, Kyung-Joong Kim, Jong-Yoon Chun, Chun Kang, Yoon-Seok Chung, Hyang-Min Cheong
Clin Exp Pediatr. 2006;49(4):401-409.   Published online April 15, 2006
목 적 : 호흡기 감염증의 주된 원인 중 하나인 hMPV가 2001년 van den Hoogen 등에 의해 네덜란드에서 처음으로 발견된 후 여러 나라에서 보고되었지만, 국내에서 hMPV의 검출에 대한 보고는 대단히 드물다. 따라서 저자들은 우리나라에서 hMPV의 역학을 연구하고자 하였다. 방 법 : 2004년 10월부터 2005년 5월까지 순천향대학교 천안병원 소아과에 급성 하기도염으로 입원한 218명의 비인두 흡인액을 추출한 뒤 RT-PCR을 시행하고, hMPV가 검출된 환아들의 비인두...
Organic acidemias in Korea - Eight years experience of organic acid analysis -
Jun Suck Bang, Si Hong Lim, Kyung Hwa Lee, Eun Joo Bae, Won Il Park, Hong Jin Lee
Clin Exp Pediatr. 2006;49(3):258-267.   Published online March 15, 2006
Purpose : We have done this retrospective study to know the relative incidence and clinical manifestations of organic acidopathies in Korea during 8 years(from Jul. 1997 to May 2005). This results of organic acid analysis of 1,787 patients were compared with the results of organic acid analysis that were published three years ago. Methods : The results of quantitative organic acid...
Usefulness of Korean Infant Developmental Screening Test in Premature Infants
Dong Han Shin, Hee Sun Lee, Jee Yeon Lee, Byung Min Choi, Baik-Lin Eun, Young Sook Hong, Joo Won Lee
Clin Exp Pediatr. 2005;48(12):1337-1341.   Published online December 15, 2005
Purpose : This study aimed to evaluate the usefulness of Korean Infant Development Screening Test in predicting delayed development in premature infants. Methods : A total of 74 children with histories of prematurity, who visited the pediatric neurology clinic of Korean University Ansan Hospital from August, 2002 to July, 2004, were examined, using the Korean Infant Development Screening Test. They were...
Clinical and Laboratory Features of Korean Mucopolysaccharidoses (MPSs)
Woo Yun Sohn, Jee Hyun Lee, Kyung Hoon Paik, Eun Kyoung Kwon, Ahn Hee Kim, Dong Kyu Jin
Clin Exp Pediatr. 2005;48(10):1132-1138.   Published online October 15, 2005
Purpose : The mucopolysaccharidoses (MPSs) are a heterogeneous group of lysosomal storage disorders. They are caused by a deficiency of the enzymes involved in the degradation of glycosaminoglycans. Early recognition is important because recombinant enzyme replacement therapy is now available for MPS. We studied the clinical characteristics of 80 MPS children with the object of determining the epidemiological, clinical and...
Clinical Findings of Genotypes in Korean Patients with Glycogen Storage Disease Type Ia
Jae Sung Ko, Hye Ran Yang, Jong Won Kim, Jeong Kee Seo
Clin Exp Pediatr. 2005;48(8):877-880.   Published online August 15, 2005
Purpose : Glycogen storage disease type Ia(GSD Ia) is an autosomal recessive disorder caused by the deficiency of glucose-6-phosphatase(G6Pase). The aim of the study was to investigate the spectrum of G6Pase gene mutations and relationship between genotype and clinical findings in Korean patients with GSD Ia. Methods : Genomic DNA was extracted from peripheral leukocytes of 20 patients with GSD...
Tibial Torsion in Children of the Jeju Area
Dong Ho Song, Baik-Lin Eun, Sang Hee Park, Joon Young Lee, Young Chang Tockgo
Clin Exp Pediatr. 2005;48(1):75-80.   Published online January 15, 2005
Purpose : Internal tibial torsion is prevalent in East Asian countries such as Korea and Japan, where sitting on the floor is common behavior. Internal tibial torsion or excessive lateral tibial torsion may cause esthetical, functional, or psychological problems and also may induce degenerative arthritis in older age. The purpose of this study is to measure the tibial torsion in...
Congenital Heart Disease in Jeju : Postnatal Incidence and Clinical Features
Jung Ha Lee, Gyu Hong Shim, Kyung Sue Shin, Jung Yun Hong, Yeoun Woo Kim, Seong Ho Kim, Chung Il Noh
Clin Exp Pediatr. 2004;47(3):294-303.   Published online March 15, 2004
Purpose : This is a retrospective descriptive study to determine the incidence of congenital heart disease(CHD) in Jeju and to estimate the suitability of the Jeju population as the subject for a regional birth cohort study. Methods : All patients with CHD diagnosed by two dimensional echocardiography in Cheju National University Hospital and Halla General Hospital from January 1999 to...
Trend of Obesity in School Age Children in Seoul Over the Past 23 Years
Young Shin Park, Dong Hwan Lee, Joong-Myung Choi, Yun Ju Kang, Chong Hee Kim
Clin Exp Pediatr. 2004;47(3):247-257.   Published online March 15, 2004
Purpose : The aim of this study was to evaluate the change in prevalence and the epidemiology of obesity in school age children of Seoul, Korea during the last 23 years with coherency and under the same standards. Methods : We used the new 1998 standard weight for height to calculate obesity on the personal data from five years and produced...
Organic Acidemias in Korea - Three Years Experience of Organic Acid Analysis -
You Kyoung Choi, Eung Seok Kim, Eun Joo Bae, Won Il Park, Kyung Ja Lee, Hong Jin Lee
Clin Exp Pediatr. 2002;45(11):1346-1358.   Published online November 15, 2002
Purpose : We have done this retrospective study to know the relative incidences and clinical manifestations of organic acidopathies in Korea. Methods : The results of quantitative organic acid analysis of 1,125 samples of 712 patients, referred from Jul. 1997 to Jun. 2000, were analyzed retrospectively according to four age groups (-2 mon, 3 mon-2 year, 3 years-12 years, over...
Renal Anomalies in Children with Turner Syndrome
Ji Young Kim, Sun Young Hong, Young Mi Park, Yong Hoon Park, Woo Yeong Chung
Clin Exp Pediatr. 2002;45(7):891-895.   Published online July 15, 2002
Purpose : The prevalence of renal anomalies in Turner syndrome(TS) has been reported to vary from 33% to 60%. The purpose of this study was to clarify the true incidence of renal malformations in Korean TS. Methods : We evaluated 33 patients with Turner syndrome diagnosed by karyotype in Inje University Busan Paik hospital and Youngnam University from January 1995....
Quantification of Age-related Reference Values for Urinary Organic Acids in the Healthy Korean Population
Yong Jae Choi, In Cheol Kim, You Kyoung Choi, Hong Jin Lee, Bong Sung Kim, Won Il Park, Kyoung Ja Lee, T. Giudic, M. Blaskovics
Clin Exp Pediatr. 2001;44(12):1413-1423.   Published online December 15, 2001
Purpose : For the accurate diagnosis of organic acidopathies, quantification of urinary organic acid should be done and we should know the normal ranges of each organic acid excreted in the urine. The amount of organic acids excreted in the urine shows wide variability according to ethnic group, diet and age. We have quantified 82 organic acids to make a Korean reference value. Methods...
Clinical Trends in Acute Rheumatic Fever in Korean Children : Mailed Questionnaire Survey from 1988 to 1997 (Compared with 1978-1987)
Hyeon-Ho Kang, Sung-Ho Cha, Kyong-Su Lee, Sang-Bum Lee, Tae-Chan Kwon, Young-Chang Tockgo, Chang-Sung Son, Jin-A Son, Hee-Ju Park, Yong-Soo Yun, Jung-Yun Choi, Chang-Hwi Kim, Chul-Ho Kim, Tai-Ju Hwang, Jae-Sook Ma, Chan-Uhng Joo, Nam-Su Kim
Clin Exp Pediatr. 1999;42(10):1381-1391.   Published online October 15, 1999
Purpose : The purpose of this study was to assess the frequency of acute rheumatic fever(ARF) among children in Korea and to describe trends in its clinical characteristics compared to data from a previous study(1978-1987). Methods : A mailed questionnaire survey sent to the pediatric departments of 13 general hospitals in Korea requested the total number of patients with ARF and...
Survey of Harada Scoring of Occurrence of Coronary Aneurysm in Kawasaki Disease Compared to Current Criteria
Chang Kyu Nam, Yong Wook Kim, Ki Bok Kim
Clin Exp Pediatr. 1999;42(7):928-935.   Published online July 15, 1999
Purpose : Gamma-globulin is effective in preventing coronary aneurysm, the primary complication of Kawasaki disease(KD). However, in order to predict high-risk cases which absolutely require γ-globulin, because of its high expenses, Harada score(HS) was introduced in Japan in 1990. We attempted to compare HS scoring with the health insurance criteria currently used in Korea. Methods : Retrospective studies were performed on...
A Study for Causes of Death in Korean Children
Ha Baik Lee, Jun Hee Sul, Young Yull Koh, Jong Wan Kim, Young Jin Hong, Nam Su Kim, Myung Ik Lee
Clin Exp Pediatr. 1998;41(8):1047-1059.   Published online August 15, 1998
Purpose : Analyzing of the causes of childhood death will provide us with the basis to understand prevalent diseases and to make the best possible health plan according to the studies. The National Statistical Office(NSO) of Korea has released an annual report of nationwide death. However, it could have underestimated the death toll of children because of delayed or missing...
The Effect of Acanthopanax koreanum Extract on the Induction of Collagen Induced Arthritis for DBA/1J Mice
Dong Soo Kim, Chang Ho Song, Soo Kon Lee
Clin Exp Pediatr. 1998;41(2):247-254.   Published online February 15, 1998
Purpose : It is well known that the Acanthopanax koreanum extract has an anti-inflammatory action without any adverse effects reported. We conducted this study to see whether the Acanthopanax koreanum extract has a preventive effect on the development of collagen induced arthritis in DBA/1J mice. Methods : Three groups of BDA/1J mice were immunized by intradermal injection of 2mg/kg bovine type...
Auditory Brainstem Responses in Premature and Fullterm Infants
Hyun Mi Kim, Tae Sung Ko, Ki Soo Kim, Moo Song Lee, Kyung Hee Kim
Clin Exp Pediatr. 1995;38(8):1036-1045.   Published online August 15, 1995
Purpose : We tried to know normal range of auditory brainstem responses in premature and fullterm infants who have no rksk factor during perinatal period and to determine that the abnormal ABR in premature and fullterm infants may predict developmental delay. Methods : ABR evaluations were performed on 283 premature and fullterm infants from NICU of the Asan Medical Center during...
Study on Child Mortality among Korean Children
Beom Soo Park, Moo Song Lee, Seung Pil Jeong, Yoon Ok Ahn
Clin Exp Pediatr. 1994;37(9):1264-1272.   Published online September 15, 1994
To estimate the child and infant mortality rates among Korean children, a mortality survey was carried out in the province of Kyongsangnam¡¤buk-do. The study popolation are the beneficiaries of Korea Medical Insurance Coorporation(KMIC), Kyongsangnam¡¤buk-do area, among which the 3,867 and 1767 deaths occurred from Januray, 1989 to December, 1990 in Kyongsangnam-do area and from January, 1991 to December, 1991 in...
Prevalence of Epstein-Barr Virus (EBV) Antibody in Korean Children
Sei Ho Oh, Young Ah Lee, Woong Young Moon, Tae Sun Won, Young Seo Park, Hyung Nam Moon, Chang Yee Hong, Dae Won Kim
Clin Exp Pediatr. 1994;37(6):804-811.   Published online June 15, 1994
Recently, cases with typical clinical manifestations of infectious mononucleosis are increasing in Korea. So, to evaluate the recent epidemiology of EBV infection in Korea, we performed EBV serologic antibody tests for IgG antibody to EBV-viral capsid antigen (VCA) and antibody to EBV-associated nuclear antigen (EBNA) among the 108 healthy Korean infants and children whose ages were from newborn to 15...
Blood Pressure Measurement of School-Aged Children in Goesan
Seong Hoon Hah
Clin Exp Pediatr. 1993;36(5):705-713.   Published online May 15, 1993
Since clinical significance of blood pressure level in childhood has been known, a several studies for the purpose of establishing normal blood pressure referce values in Korean school-aged children were performed. The author of this article measured normal blood pressure values for children in an elementary school, and two middle schools of Korean rural area using mercury sphygmomanometer. The results...
Standard of Ear Size in Korean Children
Heon Seok Han, Hyung Ro Moon
Clin Exp Pediatr. 1992;35(8):1089-1095.   Published online August 15, 1992
Measurement of 1298 Korean Children in Seoul (male 661; female 637) resulted in normal standard data for ear length and width by their age and sex. 1) Ear length and width were as follows respectively : 36.0¡¾2.5mm 21.5¡¾2.5mm in male neonate, 56.3¡¾3.1mm 30.6¡¾3.2mm at 6yr boy, 63.2¡¾3.5mm 33.4¡¾3.2mm in 14 yr adolescent male, 35.5¡¾2.0mm 21.2¡¾2.1mm in female neonate, 54.6¡¾3.1mm 28.7¡¾2.4mm in...
Incidence Estimation of Leukemia among Korean Children
Hong Hoe Koo, Hee Young Shin, Hyo Seop Ahn, Yoon-Ok Ahn
Clin Exp Pediatr. 1992;35(1):80-87.   Published online January 15, 1992
Leukemia is a neoplasm arising from the malignant transformation of hematopoietic cells. The incidence data of leukemia have not been available for Korean as a whole. The present study was therefore undertaken in order to estimate the incidence of childhood leukemia among Korean. The study population of this investigation was the beneficiaries of the Korea Medical Insurance Corporation(KMIC) during the period...
A study for mass screening of galactosemia using galactitol level by spot urine method among Korean infants.
Jin Tae Kim, Chong Won Bae, Sa Jun Chung, Chang Il Ahn, Suyama I , Isshiki G
Clin Exp Pediatr. 1991;34(7):949-958.   Published online July 31, 1991
For mass screening of the galactosemia, we used spot urine method using filter paper which was newly developed by Department of Pediatrics, Kyung Hee University Hospital and Department of Pediatrics, Osaka City University in Japan. We used control groups as followed, 7 of normal adults,- one patient of I, II, III types of galactosemia, respectively. The experimental groups were 62 infants of 0 to...
Seventeen Years Experience on Inborn Errors of Metabolism A Study for Future Development of Inborn Errors of Metabolism in Korea.
Hong Jin Lee, Hyung Ro Moon
Clin Exp Pediatr. 1990;33(8):1031-1036.   Published online August 31, 1990
In Korea, the study of inborn errors of metabolism is very primitive. Even the incidence and prevalence of the disease of inborn errors of metabolism are not known in Korea. We have done this study of inborn errors of metabolism in Korea and concluded that: 1) The varieties and incidences of inborn errors of metabolism in Korea might be relatively diverse and high. 2) Nation wide mandatory...
Clinical Study of 12 Cases of Korean Hemorrhagic Fever in Childhood.
Dae Kyung Ko, Keyun Haeung Cho, Ji Tae Choung, Pyung Hwa Choe
Clin Exp Pediatr. 1987;30(8):837-845.   Published online August 31, 1987
Korean hemorrhagic fever (KHF) is an acute, rodent-bom, viral illness (Hantaanvirus) which is characterized by widespread abnormalities of blood vessels, chiefly arterioles and capillaries. The vascular abnormaliteis lead to impairment of function in a number of organs with resulting bleeding tendency and renal failure. KHF was recognized for the first time in Korea in 1951. In recnt years the disease has invaded the southern parts...