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Original Article
Plasma Fibronectin Concentration in the Neonate
Young Yoo, Kwang Chul Lee, Young Chang Tockgo
Clin Exp Pediatr. 1996;39(3):319-325.   Published online March 15, 1996
Purpose : Plasma fibronectin is thought to have important role in the inflammatory response and host defense. We performed this study to evaluate concentration in the full-term, healthy preterm, asphyxia and respiratory distress syndrome and how that correlated with gestational age and birth weight. Methods : We evaluate 51 neonates who were delivered at Korea University Hospital from Jan. 1992 to...
The Study of Distribution of HI Antibody Titers Aganist Japanese Encephalitis Virus Among Children in Seoul
Jin A Kim, Tae Sung Ko, Young Seo Park, Hyung Nam Moon, Chang Yee Hong, Hae Wol Cho
Clin Exp Pediatr. 1996;39(2):230-237.   Published online February 15, 1996
Purpose : Incidence of Japanese encephalitis has been markedly decreased, but this disease is known to be high and lethal in the young age group. This study was designed to find out the HI antibody titers and associated factors of Japanese encephalitis of children in Seoul, and to establish the plan of vaccination. Methods : The survey was conducted from the...
Surfactant Protein SP-A, B, and C: Purification and Biochemical Characterization
Chong-Woo Bae, Yong-Mook Choi, Joo Hyun Kang, Kil Lyong Kim, Kyung Soo Hahn
Clin Exp Pediatr. 1996;39(2):218-229.   Published online February 15, 1996
Purpose : Several kinds of exogenous pulmonary surfactants (SF), either synthetic or animalderived, are being used for the replacement therapy in respiratory distress syndrome (RDS) of newborn, especially in premature infants, and improved the neonatal mortality and morbidity. Because synthetic preparations are lack of surfactant protein (SP) and animal-derived preparations cause immunogenecity of heterogenous SP, there have been great necessity for the development of next...
Case Report
A Case of Cerebral Infarction Associated with Mycoplasma pneumoniae Infection
Young Jae Koh, Dong Jun Kim, In Joon Seol, Ha Baik Lee, Ki Woong Hong
Clin Exp Pediatr. 1996;39(1):115-119.   Published online January 15, 1996
Mycoplasma pneumoniae has been shown to be of etiologic importance in cases of upper-and lower-respiratory tract infections, especially in children and young adults. It may cause a variety of extrapulmonary manifestations in multiple organ systems, most commonly the central nervous system. The extrapulmonary syndromes include meningitis, cerebral infarction, acute transverse myelitis, psychosis, cerebellar ataxia, Guillain-Barré syndrome and Reye syndrome. Cerebral...
Original Article
Study on the Thyroid Function of Neonate Born to Mother with Hyperthyroidism
Choong Ho Shin, Se Young Kim, Sei Won Yang, Jung Hwan Choi, Chong Ku Park
Clin Exp Pediatr. 1996;39(1):106-114.   Published online January 15, 1996
Purpose : In newborns from mothers with Graves' disease, neonatal transient hyperthyroidism or hypothyroidism may develop early in life. We evaluated the incidence and prognosis of neonatal thyroid dysfunction in neonates born to mothers with hyperthyroidism during pregnancy. Methods : We measured blood T4, T3, TSH levels and TSH-R-Ab titer in 48 hyperthyroid mothers and their babies between 1988 and 1994. Results :...
Evaluation of Abnormal Coronary Artery Flow in Anomalous Coronary Artery Connections by Pulsed and Color Doppler Echocardiography
Young Mi Hong
Clin Exp Pediatr. 1996;39(1):78-87.   Published online January 15, 1996
Purpose : Anomalous connection of coronary artery can result in damage of myocardial perfusion, myocardial infarction, or congestive heart failure. Echocardiography has been used to demonstrate coronary artery anomalies such as coronary artery fistula, anomalous origin of the left coronary artery from the pulmonary artery, and aneurysm of the coronary arteries in Kawasaki disease. Definitive diagnosis relies on cardiac catheterization The...
Early Postoperative Results of the Large Ventricular Septal Defect in Infants Younger Than 1 Year of Age
Man-Teak Oh, Hyang-Suk Yoon, Jong-Bum Choi
Clin Exp Pediatr. 1996;39(1):72-77.   Published online January 15, 1996
Purpose : We report the results of a policy of primary surgical closure of large ventricular septal defects(VSDs) applied over the past 3 years to all symptomatic infants regardless of patient weight, location or number of VSDs. To analyze the early postoperative mortality and other surgical complications in young infants, comparison of preoperative and outcome variables were made between infants...
Pulmonary Function Test in Korean Neonates by Expiratory Flow-Volume Curve
So Young Park, Kyung Hyo Kim, Gyoung Hee Kim
Clin Exp Pediatr. 1996;39(1):53-62.   Published online January 15, 1996
Purpose : Neonatal pulmonary function test(PFT) adds a new dimension to the understanding and care of the infant at risk for lung dysfunction. PFT can be identified the risk for pulmonary problems and safely and effectively diagnosed, quantified, and qualified the dysfunction. So it is possible to early institution of prophylatic respiratory therapy in such neonates and it can improved...
Erratum
Breast Feeding: A Neurobiologic Perspective
Jan Winberg
Clin Exp Pediatr. 1996;39(1):36-41.   Published online January 15, 1996
Breast-feeding(BF) failures are common in industrialized societies and can only partly be explained by social, psychologic, culturaland cognitive factors. The more profound causes remain unknown. This annotation presents clinical observations suggesting that several nursing care rituals in delivery rooms and maternity wards interfere with innate behavioural programs and consequently may disturb the unfolding feeding behaviour. Mother-infant interaction including BF depend on the activation of acomplex network...
Original Article
Responses to Growth Hormone Treatment in Children with Short Stature Secondary to Intrauterine Growth Retardation
Byung Churl Lee, Dong Won Kin, Byung Kyu Suh
Clin Exp Pediatr. 1995;38(12):1671-1676.   Published online December 15, 1995
Purpose : Several studies recently have emphasized the value of sonography as an new therapeutic method for hydrostatic reduction of intussusception by using a saline enema under ultrasound guidance. The purpose of this study was to asses the diagnostic screening efficacy of sonography in suspected childhood intussusception and the value of ultrasound guidance in hydrostatic reduction performed with saline enema. Methods...
Comparison of Diagnostic and Therapeutic Efficacy between Ultrasound Guided Hydrostatic Saline Reduction and Fluoroscopic Barium Reduction in Children with Intussusception
Chi Hyung Park, Ho Seok Lee, Chong Woo Bae, Sa Jun Chung, Young Mook Choi, Sun Wha Lee, Yup Yun
Clin Exp Pediatr. 1995;38(12):1664-1670.   Published online December 15, 1995
Purpose : Several studies recently have emphasized the value of sonography as an new therapeutic method for hydrostatic reduction of intussusception by using a saline enema under ultrasound guidance. The purpose of this study was to asses the diagnostic screening efficacy of sonography in suspected childhood intussusception and the value of ultrasound guidance in hydrostatic reduction performed with saline enema. Methods...
Evaluation of Severity of Childhood Pancreatitis with Multiple Factor Scoring Systems
Young In Choi, Jeong Kee Seo
Clin Exp Pediatr. 1995;38(12):1653-1663.   Published online December 15, 1995
Purpose : Pancreatitis in children is not common but can be associated with severe morbidity rates. Early prognostic evaluation of acute pancreatitis assists in selecting those patients who should be closely monitored. We studied the clinical characteristics and prognostic factors in patients with acute pancreatitis. Methods : Twenty five children with pancreatitis were included ranging in age from 1.8 to 14.9...
Changes of Cerebral Blood Flow Velocity before and after Closure of Ductus Arteriosus using Doppler Ultrasound in Normal Full-term Newborns
Myung Su Lee, Young Mi Hong, Kyung Hee Kim
Clin Exp Pediatr. 1995;38(12):1620-1628.   Published online December 15, 1995
Purpose : With PDA, major fluctuations of blood flow are noted between opening and closure of ductus arteriosus and there is an increase in the amplitude of each pulse of blood flow. The purpose of this study was to evaluate the changes of cerebral blood flow before and after closure of ductus arteriosus in healthy term newborns. Methods : Forty-two normal term...
Case Report
A Case of Renal Hypoplasia with Renovascular Hypertension
Sang Doo Lee, Jae Hee Park, Jae Beom Lee, Yun Duk Yoo, Byoung Hwa Lee, Mi Sun Lee
Clin Exp Pediatr. 1995;38(11):1565-1570.   Published online November 15, 1995
Renal hypoplasia is a condition in which the kidneys are small because of developmental parenchymal deficit. Essential to this definition is the notion of normally developed and differentiated individual nephrons and ducts, without coexisting dysplasia. Affected renal artery and intrarenal blood vessel branches are relatively hypoplastic and commonly sclerotic. Stenosis of main arteries or its branches are apt to cause...
Original Article
Prevelance and Associated Factors of Childhood Obesity on the Elementary Students in Kwangju City
Myoung Sook Chung, Yung Il Rho, Eun Gyeoung Jung, Kyung Rye Moon, Sang Gee Park, Young Bong Park, So Yeon Ryu, Jong Park
Clin Exp Pediatr. 1995;38(11):1547-1557.   Published online November 15, 1995
Purpose : The prevalence of childhood obesity and its attendant morbidity have increased and the success of therapy for childhood obesity has been limited. It is important for us to recognize risk factors for the development of obesity in children. The purpose of our study is to provide useful information for the prevention and treatment of childhood obesity. Methods : A...
Ischemic Hepatitis in Children after Cardiac Operation -Analysis of Clinical Characteristics, Risk Factors and Outcome-
Kyung Mo Kim, Jeong Kee Seo
Clin Exp Pediatr. 1995;38(11):1540-1546.   Published online November 15, 1995
Purpose : We have experienced frequently the ischemic hepatitis after cardiac operations which shows rapid striking rise of transaminase. But the ischemic hepatitis in children after cardiac operation is not defined yet in Korea. We examined the clinical characteristics and analyzed the risk factors and outcome in 20 children who showed typical clinical course of ischemic hepatitis after cardiac operation. Methods...
A Follow-Up Study of Intractable Diarrhea in Early Infancy: Clinical Features of Cow's Milk Allergy and Cow Milk-Sensitive Enteropathy
Young Rak Kwon, Young Ho Ahn, Jin Bok Hwang, Chang Ho Han, Hai Lee Chung, Young Dae Kwon
Clin Exp Pediatr. 1995;38(11):1515-1524.   Published online November 15, 1995
Purpose : The multiplicity of poorly defined illnesses and the variability of clinical and laboratory features elicited by milk ingestion in sensitized infants has made it difficult to differentiate them from the more common forms of cow milk intolerance. Following up the cases of intractable diarrhea in early infancy(illI), We investigated the clinical features of cow's milk allergy(CMA) and cow...
A Clinical Evaluation of the Gastrofiberscopy Studies in Children
Jung Ah Park, Young Ho Ahn, Jin Bok Hwang, Chang Ho Han, Hai Lee Chung, Young Dae Kwon, Jae Bok Park
Clin Exp Pediatr. 1995;38(11):1498-1505.   Published online November 15, 1995
Purpose : This study aimed to provide, as basic material, the experience of gastrofiberscopy in children and the clinical significance of Helicobacter pylori(H. pylori) infection in pediatric gastrointestinal disease. Methods : The objects were 99 patients(male 49, female 50) who underwent gastrofiberscopic examination in case of endoscopic indication at department of pediatrics of Taegu Hyosung Catholic University Hospital from March 1993...
Respiratory Syncytial Virus Infections and Application of Nested Reverse Transcription-Polymerase Chain Reaction
Kon-Hee Lee, Hae-Sun Yoon, Kyu-Man Lee, Kyung-Hee Kim, Yang-Ja Cho
Clin Exp Pediatr. 1995;38(11):1486-1497.   Published online November 15, 1995
Purpose : Respiratory syncytial virus(RSV) in the most common cause of bronchiolitis and pneumonia in chileren less than 2 years old. Complications of RSV infections may be life-threatening in children who are immunosuppressed or who have congenital heart disease. Thus it is imperative that laboratory results be rapid and accurate. We therefore were interested in evaluating the role of RSV...
Clinical Characteristics of Patients with Tumer' Syndrome according to Karyotypic Differences
Eun Young Kim, Kyoung Sim Kim, Kibok Kim, Won Jin Kee
Clin Exp Pediatr. 1995;38(11):1460-1469.   Published online November 15, 1995
Purpose : To assess the differences of clinical features according to various karyotypes in Turner syndrome. Methods : Subjected to study were 45 patients with Turner syndrome, including 5 newborns, from March 1974 to April 1994. They were divided into 3 groups according to karyotypes: 45,X, mosaicism, and structural aberration; and the clinical features were compared. Also structural aberration groups, 46,XXp-and...
The Changes of Thyroid Function Tests and TSH Receptor Antibody Levels During Antithyroid Drug Therapy of Graves Disease in Children
Jeong-Ho Kim, Eun-Young Cho, Han-Wook Yoo
Clin Exp Pediatr. 1995;38(10):1404-1410.   Published online October 15, 1995
The mainstay of treatment in children with Graves' disease is antithyroid drug therapy. Most commonly used drugs are methimazole(MMI) and propylthiuracil(PTU). These drugs inhibit thyroid hormone synthesis through mechanisms that interfere with the action of thyroid peroxidase. Since antithyroid drugs are unable to inhigit the secretion of thyroid hormone which is already produced, it takes 2 to 3 weeks for...
Results of the Mechanical Valve Replacement in the Right Side of the Heart in Children
Hyeon Jin Park, Chung Il Noh, Ho Sung Kim, Jung Yun Choi, Yong Soo Yun, Yong Jin Kim
Clin Exp Pediatr. 1995;38(9):1220-1231.   Published online September 15, 1995
Purpose : We performed this study in order to evaluate the outcome of the mechanical valve replacement in the right side of the heart in children. Methods : Retrospective analysis of the clinical records of 26 patients who had undergone a right sided valve replacement between October 1986 and September 1992 at Seoul National University Children뭩 Hospital. Results : Twenty six children...
A Study of Relationship between Bronchial Hyperreactivity (BHR) and Atopic Findings in Mycoplasma pneumoniae Pneumonia
In Kyeong Seo, Weon Jeong Bae, Jae Ook Lee, Im Ju Kang
Clin Exp Pediatr. 1995;38(9):1210-1219.   Published online September 15, 1995
Purpose : The respiratory infection due to Mycoplasma pneumoniae among school aged children and adolescents was recognized as an important cause of wheezing or BHR. This study was performed to evaluate relationship between BHR to Mch inhalation challenge and atopic findings in M. pneumoniae pneumonia. Methods : 61 patients with M. pneumoniae pneumonia who were admitted to the department of Pediatrics,...
Case Report
A Case Report of Acrorenal Syndrome
Soo Hee Chang, Jo Seph Choi, Soo Chul Cho, Dae Yeol Lee
Clin Exp Pediatr. 1995;38(8):1151-1154.   Published online August 15, 1995
Acrorenal syndrome is congenital anomaly of the limbs and urinary tract of unknown etiology. Acral malformations consist of varying combinations of oligodactyly, ectrodactyly, syndactyly, brachydactyly, polydactyly, and carpal, tarsal, or metatarsal fusions of the hands and feet. Urinary tract abnormalities include unilateral renal agenesis and duplication of the collecting system. The condition is a polytopic developmental field defect(acrorenal field) and...
Original Article
Effects of Main Pulmonary Artery Constriction on the Right Ventricle in Rabbits
Chan Uhno Joo, Dong Geun Lee
Clin Exp Pediatr. 1995;38(8):1087-1092.   Published online August 15, 1995
Purpose : constriction or banding of the pulmonary artery tocreate pulmonalry artery stenosis is a palliative procedure designed to limit pulmonary blood flow in congenital cardiac malformation with unrestricted shunt flow from the systemic to pulmonary circuit. Increased pressure-load with the procedure results in ventricular hypertrophy in right ventricle. We studied effects of the pulmonary artery constriction on the right ventricle...
Detection of Mycoplasma pneumoniae in clinical Samples from Pediatric Patients by Polymerase Chain Reaction
Baik-Lin Eun, Sang Hee Park, Young Chang Dockgo, Sang Chul Seong
Clin Exp Pediatr. 1995;38(8):1077-1086.   Published online August 15, 1995
Purpose : Mycoplasma pneumoniae is a common cause of a wide rage of upper and lower respiratory tract infections, especially in children and young adults. Routine laboratory diagnosis of M.pneumoniae infection is based mainly on serology and, to lesser extent, on cultivation. The cultivation of M.pneumoniae, a fastidious microorganism, is time-consuming and may require 1-3 weeks for results. Serological procedures...
Clinical and Histologic Findings and their Correlations in Children with Nodular Gastritis
Ki Moon Cha, Gi Euin Won, Hann Tchah, Ho Jin Park, Mi Kyoung Shin
Clin Exp Pediatr. 1995;38(8):1069-1076.   Published online August 15, 1995
Purpose : Recently, a wide application of gastrofiberscopy in the pediatric group have revealed that nodular gastritis is an unique disease in children and associated with Helicobacter pylori. The aim of this prospective study was to investigate the clinical and histologic features in children with nodular gastritis, and to assess corelation between both. Methods : During a period of 44 months(May 1991-December...
Case Report
A Case of the Non-rhizomelic Chondrodysplasia Punctata
Son Ill Jin, Kyung Rye Moon, Sang Kee Park, Young Bong Park, Young Suk Kim
Clin Exp Pediatr. 1995;38(7):1000-1005.   Published online July 15, 1995
Chondrodysplasia punctata is a rare congenital disorder of bone, which is characterized by radiographic manifestation of punctate calcification in epiphyseal areas, preformed in cartilage. We experienced a case of the non-rhizomelic chondrodysplasia punctata in a male neonate who showed cataract, saddle nose, stippled calcification on X-ray without coronal cleft of verte-brae and rhizomelia.
Original Article
Intractable Diarrhea in Early Infancy : Clinical Features on Admission and A Nutritional Management
Jong Won Shin, Kyung Won Hwang, Young Ho Ahn, Jin Bok Hwang, Chang Ho Han, Hai Lee Chung, Young Dae Kwon
Clin Exp Pediatr. 1995;38(7):936-945.   Published online July 15, 1995
Purpose : We studied to assess the value of clinical findings on admission in screening of intractable diarrhea in early infancy(IDI) and the efficiency of early trial of semi-elemental form-ula (protein hydrolysate) as a nutritional management in IDI. Methods : We carried out a retrospective review of medical records of twenty-eight early infants with diarrhea and malnutrition who were diagnosed as...
Studies on Mechanism of Vascular Hyporeactivity of Mesenteric Artery from Septic Rats
Man Chul Ha, Hee Ju Park, Ki Whan Hong
Clin Exp Pediatr. 1995;38(7):922-935.   Published online July 15, 1995
Purpose : Septic shock due to gram negative bacterial infection is characterized by vasodil-ation, hypotension, and myocardial depression due to the effect of lipopolysaccharide (LPS). In spite of extensive studies, the mechanisms for the vascular effects of endotoxemia are not clear. Recently, it has been proposed that nitric oxide (NO) synthesized from L-arginine by nitric oxide synthase contributes to the...