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Original Article
The Change of Anti-HBs Titer after Hepatitis B Vaccination in Newborn.
Ji Hye Kang, Young Mi Hong, Seung Joo Lee
Clin Exp Pediatr. 1990;33(5):598-605.   Published online May 31, 1990
Hepatitis B vaccination is an accepted preventive measure for all newborn as well as the risk group. However, there is some uncertainty about the persistence of anti-HBs and the timing of booster vaccination. We studied anti-HBs titer, positive rate and minimum protective rate in relation to time interval after the third vaccination in 102 infants bom to HBsAg negative mother (Group I) and 52...
A case of Transient Tricuspid Insufficiency of Newborn(TTI).
Young Kyoo Shin, Eui Kyung Jung, Sang Hee Kim, Chang Sung Son, Joo Won Lee, Young Chang Tockgo
Clin Exp Pediatr. 1990;33(4):534-538.   Published online April 30, 1990
Transient Tricuspid Insufficiency(TTI) of newborn is a feature of myocardial dysfunction caused by myocardial hypoxemia secondary to reduced arterial oxygen content and excessive right ventricular work consequent to pulmonary hypertension.' Since Doppler echocardiography has been used to diagnose cardiac disease, it allows recording of regurgitant turbulent flow pattern. We report one case of TTI in a 36 week-gestational-aged newborn detected by continuous wave Dopplar echocardiography...
Hematologic Reference Values of Peripheral Blood in Healthy Newborns and Infants.
Nam Hyuk Joo, Hong Ja Kang, Soon Ho Kim
Clin Exp Pediatr. 1990;33(4):481-490.   Published online April 30, 1990
To estimate hematologic reference values of the peripheral blood of newnboms and infants, the author examined the routine hematologic parameters by heel or finger puncture in 73 cases of first day newborn, 64 cases of 7 day newborns, 10 cases of 2 month infants, 14 cases of 3~6 month infants and 13 cases of 15~18 month children. The routine hematologic parameters including red cell...
Posterior Nasal Swab Culture in Normal Newborns by Feeding Method.
Young Youn Choi, Tai Ju Hwang, Jae Sook Ma, Kwang Ok Lee, Byung Hee Kim, Young Soo Chung, En Kyeong Bom, Too Yong Yoo
Clin Exp Pediatr. 1990;33(4):472-480.   Published online April 30, 1990
To evaluate the difference of normal flora between breast and formula-fed newborns, we performed quantitative posterior nasal swab culture in 21 breast-and 44 formula-fed newborns. Positive culture rates of total aerobes and total anaerobes were 100% and 98%, respecitively. Among the aerobes, positive culture rate was 100% in group B streptococcus, 98% in gram negative bacteria, 86% in staphylococcus aureus, 82% in staphylococcus epidermidis...
Effect of Position Change on TcPO2 in the Newborns.
Young Pyo Chang, Yong Joon Shin, Myoung Jae Choey, Beyong Il Kim, Jung Hwan Choi, Chong Ku Yun
Clin Exp Pediatr. 1990;33(4):448-455.   Published online April 30, 1990
To determine the optimal position for the neonatal intensive care, transcutaneous oxygen tension (TCPO2) was monitored in 20 healthy preterm infants and 20 healthy term infants using the Radiometer Tc Oxgen Monitor in both supine and prone position. Also, transcutaneous oxygen tension (TcPO2) was monitored with tilting change in each position. When the infants were prone, TcPO2 rose by a mean of 7.36 mmHg...
Clinical Evaluation on Newborn of Teenage Pregnancy.
Man Cheol Ha, Chan Yung Kim
Clin Exp Pediatr. 1990;33(3):306-314.   Published online March 31, 1990
The authors have analysed the clinical characteristics of 117 cases of teenage pregnancy and their 122 newborn cases who were visited Pusan National University Hospital and Hae Sung Hospital from January 1982 to August 1988. The results were summarized as follows; 1) The youngest teenage mother was 14 years old, and below 17 years old was 28.2% and the remainder were between 18 and 19 years...
Mechanical Ventilation in Newborn Infants.
Young Back Hahm, Jong Ho Sung, In Kyung Sung, Byung Churl Lee, Du Bong Lee
Clin Exp Pediatr. 1990;33(1):10-21.   Published online January 31, 1990
Clinical analysis of 5 years* experience with mechanical ventilation of 68 neonates in NICU of St. Mary’s Hospital, from Jan. 1983 to June 1988, was done. The results were as follows; 1) Indications for mechanical ventilation were hyaline membrane disease(51.5%), postasphyxia syndrome(19.1%), apnea of prematurity (5.9%), sepsis (5.9%), intracranial hemorrhage (5.9%) and others. 2) Number of male patients was 33(48.5%》and of female was 35(51.5%), and male to female...
Study on the Temperature Measurement in the Newborn Infants.
Eun Saing Jee, Young Pyo Chang, Jung Hwan Choi, Chong Ku Yun, Yong Ran Kim, Myoung Sook Lee
Clin Exp Pediatr. 1989;32(12):1632-1636.   Published online December 31, 1989
We measured body temperatures and stabilization times of 100 term and 52 preterm infants at four sites. The sites were core, aural, rectal and axilla in order of degree of temperature. There was significant difference between term and preterm infants (term infant higher, p<0.001). Mean difference between axillary and rectal temperatures was 0.501C(rectal higher). Mean difference between rectal and core temperatures was 0.10lC(core higher)....
A case of hypertophic cardiomyopathy in newborn infant: An autopsy case.
Min Shik Kim, Eun Yong Choi, Hey Sun Lee, Young Min Ahn, Je Geun Chi
Clin Exp Pediatr. 1989;32(11):1560-1567.   Published online November 30, 1989
Hypertrophic cardiomyopathy is defined as a disorder of heart muscle of unknown cause or association, and is functionally characterized by a diastolic failure of the left ventricle due to loss of its normal distensibility. We subsequently experienced an 18 day old female newborn infant who had suffered from dyspnea, cyanosis and congestive heart failure since a few days after birth. She died of progressive...
Two Case of Transient Bilirubin Encephalopathy in Newborn.
Eun Kyoung Sohn, Chong Woo Bae, Sa Jun Chung, Chang Il Ahn
Clin Exp Pediatr. 1989;32(9):1295-1299.   Published online September 30, 1989
More recently, several studies have been repotted about the abnormalities of auditory brainstem response (ABR) in hyperbilirubinemia of newborn. By using of ABR, visual evoked potenital and nuclear magnetic resonance techniques, some investigators suggested that transient alteration in ABR in severely jaundiced neonates indicated reversible transient subclinical or clinical bilirubin induced neurotoxicity. They thought it would be the early stage of kernicterus. We experienced two...
A Study on Noninvasive Measurement of Blood Pressure in Normal Newborn.
Eun Hee Lee, Ran Namgung, Chul Lee, Dong Gwan Han
Clin Exp Pediatr. 1989;32(9):1216-1223.   Published online September 30, 1989
Measurement of blood pressure in neonate is an important diagnostic procedure. But measurement of blood pressure were not performed routinely because of difficulty in measuring blood pressure and variable normal range according to measuring apparatus. Recently some accurate and convinient apparatuses of measuring blood pressure have been introduced in neonatal care, so normal blood pressure values of neonate are needed. In this study, we establish...
A Study of Milk β-Glucuronidase Activity in Breast Milk Associating with Neonatal Jaundice.
Soo Chun Kim, Chong Woo Bae, Yong Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1989;32(9):1202-1209.   Published online September 30, 1989
Since the 1960s, several reports have been presented to explain how the ingestion of human milk is related to neonatal jaundice. Recently, the jaundiced neonates whose mother’s milk contain sub- stances (eg, pregnane 3a, 20β-diol, lipoprotein lipase, free fatty acid, β-glucuronidase etc) facilitating the reabsorption of unconjugated bilirubin in the neonatal intestine through the enhancement of the enterohepatic circulation, were called the breast milk...
Clinical Evaluation of Gastric Juice Culture of Newborn.
Byoung Hoon Lee, Back Hee Lee, Soon Wha Kim, Keum Chan Sohn
Clin Exp Pediatr. 1989;32(3):342-348.   Published online March 31, 1989
A clinical evaluation of gastric juice culture was done on 545 newborn at the N.M.C. Jan. 1st 1985 and Dec. 31, 1986. The results were as follows; 1) There were no significant statistic difference of biπh weight, gestational age, maternal age, labor duration, delivery type and duration of rupture of membrane between gastric juice culture positive and negative groups. 2) Apgar score after 1 minute was...
Acid-Base and Electrolyte Change Before and After Exchange Transfusion with ACD-B Blood in Hyperbilirubinemia of Newborn.
Ki Hong Park, Chong Woo Bae, Yong Mook Choi, Chang Ill Ahn, Jung Kook Lee
Clin Exp Pediatr. 1989;32(3):311-320.   Published online March 31, 1989
Exchange transfusion is being used widely to correct anemia and control existing hyperbilirubinemia for the prevention of kernicterus in newborn. But the blood used for exchange transfusion is stored blood containing anticoagulants and other substances. So many metabolic changes can be developed after exchange transfusion. This study was undertaken to evaluate the acid-base and electrolyte change after exchange transfusion using the ACD-B blood. In...
The Direct Coombs Test and Heat Elution Test in ABO Incompatible Hemolytic Disease of the Newborn.
Kook In PArk, Chul Lee, Ran Namgung, Dong Gwan Han, Kir Young Kim
Clin Exp Pediatr. 1988;31(12):1633-1640.   Published online December 31, 1988
The clinical study on 28 cases of ABO HDN who were diagnosed at Pediatric Department of Severance hospital and Yong Dong Severance hospital, Yonsei University for last 5 months was. And in these cases, heat elution test in combined with direct Coombs test using standard techniques were performed to evaluate the clinical significance of serological diagnosis. The following results were obtained. 1) Of 28 ABO HDN...
A Study of Maternal IgG Anti-A, B in ABO Hemolytic Disease of Newborn: Relation between Antibody titer in Mother and Clinical Severity in Neonate.
Chong Woo Bae, yong Mook Choi, Chang Il Ahn, Hyun Sook Chi
Clin Exp Pediatr. 1988;31(8):999-1006.   Published online August 31, 1988
Only IgG anti-A, or Anti-B cross the placenta and are responsible for the occurrence of ABO hemolytic disease of newbom(HDN). We have conducted the role of IgG anti-A or anti-B in mothers to occurrence and severity of the disease with were related to the level of antibodies in pathogenesis of ABO-HDN. This report presents the relation between the degree of bilirubin, hemoglobin concentration in ABO-HDN...
A Study on the Blood Pressure Measurements in Newborn.
Ran Namgung, Ki Soo Pai, Chul Lee, Dong Gwan Han
Clin Exp Pediatr. 1988;31(5):541-546.   Published online May 31, 1988
Non invasive blood pressures measured by the Dinamap monitor, an oscillometric device, were compared with the invasive radial artery pressure in neonates. There were 21 patients with a mean age of 16.5 days (ranges 7 days to 1 month) and a mean body weight of 3.3 kg. The invasive radial artery pressures were recorded on a strip chart and comparisons were made between the...
The Case of Persistent Pulmonary Hypertension of the New born.
Sung Oh Kim, Soo Yup Lee, Kyoo Hwan Lee, Soo Jee Moon
Clin Exp Pediatr. 1988;31(1):128-133.   Published online January 31, 1988
Persistent pulmoanry hypertension of the newborn (PPHN) is a syndrome consisting of severe hypoxemia and pulmoanry hypertension that appears within hours of birth. The essential pathophysiologic features of this syndrome is pulmonary artery hypertension causing right-to-left shunt through the patent ductus arteriosus or foramen ovale or both and clinically manifested by central cyanosis and respiratory distress. We recently have experienced 20 hour old female and...
Blood Pressure Change in the Neonates during Abdominal Examination.
Young Sun Kim, Yoon Deok Kim, Jung Hwan Choi, Chong Ku Yun, Son Moon Shin
Clin Exp Pediatr. 1987;30(11):1201-1206.   Published online November 30, 1987
During abdominal palpation in the 50 full term neonates, blood pressure changes were measured by automatic oscillometric blood pressure monitor. The systolic blood pressure value at resting stage was 61.2 ±2.9 mmHg, and during the liver, the left kidney and the bladder palpation, it was signifi- cantly elevated to 67.2±4.7 mmHg, 68.1 ±4.8 mmHg, 69.0±4.6 mmHg respectively (P< 0.005). The diastoloic pressure value at...
A Study on Serum Ca, P, Mg, Parathyroid Hormone, Calcitionin, and 1, 25-dihydroxyvitamin D Concentrations in Normal Newborn and Low Birth Weight Infants.
In Bock Lee, Chang Soo Ra
Clin Exp Pediatr. 1987;30(6):613-624.   Published online June 30, 1987
Early neonatal hypocalcemia occurs within the first few days of life, with the lowest concentrations of serum calcium being reached at 24 to 48 hours of age. An infant can be considered to be hypocalcemic when serum calcium concentrations are below 7 mg/dl or when ionized calcium concentrations are below 3 to 3.5 mg/dl. The most commonly encountered causes of neonatal hypocalcemia are prematurity,...
Clinical observation in the Clavicle Fracture in Newborn.
Kee Hyuck Kim, Ran Namgung, Chul Lee, Dong Gwan Han
Clin Exp Pediatr. 1986;29(12):1319-1323.   Published online December 31, 1986
The following is the result of a retrospective clinical study on the clavicle fractures iit 33 newborns who were delivered at Yonsei University Medical Center during the eight years between 1978 and 1985. 1) The incidence of clavicle fractures was 2 per 1,000 deliveries and there was no difference in incidence by sex. 2) The incidence of clavicle fracture by the birth weight was...
Aortography and Echocardiography by Countercurrent Injection Via Radial Artery in Newborns with PDA.
Jun Hee Sul, Dong Kwan Han, Sung Kyu Lee, Dong Shick Chin
Clin Exp Pediatr. 1986;29(11):1196-1200.   Published online November 30, 1986
Aortography and echocardiography by countercurrent injection into the radial artery performed for the detail diagnosis of PDA in newborns. The results were as follows： 1) Aortography by countercurrent injection via ridial artery affords an easy, safe and simple bedside means for the diagnosis of PDA without retrograde arterial catheterization, which is occasonally complicated by thrombosis of the artery in small infant....
Clinical Studies on Enteropathogenic E.Coli Enteritis in a Newborn Nursery.
Chang Hyun Yang, Ran Nam Gung, Chul Lee, Dong Gwan Han
Clin Exp Pediatr. 1986;29(11):1187-1195.   Published online November 30, 1986
We experienced 20 cases of infantile diarrhea caused by Enteropathogenic E. Coli during 2 months from May. 1985 to Jun. 1985 at Yonsei medical center, Newborn nursery. The onset of illness is ususally slow vague signs of reluctance to feed lethargy, spitting up of formula, mild abdominal distention and diarrhea. The outbreak abated abruptly after institution of strict aseptic technique,...
A Study of Blood Pressure Measurement in Newborn Infants.
Yoon Deok Kim, Joong Whan Choi, Chong Ku Yun
Clin Exp Pediatr. 1986;29(8):819-829.   Published online August 31, 1986
The inability to detect Korotkoff sounds in infants have in the past made it difficult for most pediatricians to measure blood pressures by indirect conventional sphygmomanometry. Now, however, Korotkoff sounds, or the mechanical events which produce them, can be sensed with an ultrasonic Doppler device. The author measured systolic and diastolic blood pressure using a Doppler arteriokinetog raphic instrument during 6...
A Study on Plasma Antidiuretic Hormone and Serum Sodium Levels of Cord Blood in the Newborn Infants.
Choon Ho Park, Chang Soo Ra
Clin Exp Pediatr. 1986;29(7):748-757.   Published online July 31, 1986
The authors studied the plasma antidiuretic hormone levels of cord blood in 40 cases of newborn infants and also studied the serum sodium levels of cord blood in 40 cases of newborn infants. For the purpose of analysis, the study subjects were divided into four group; 1st group of 17 cases of vaginal delivery infants with fetal distress, 2nd group...
A Study on Serum Immuoglobulins and Complements in Newborn Infants.
Song Soo Moon, Chang Soo Ra
Clin Exp Pediatr. 1986;29(1):58-71.   Published online January 31, 1986
The author investigated serum immunoglobulins (IgG, IgA, and IgM) and complements (C3and C4) of cord blood in 29 cases of normal fullterm infants, 14 cases of low birth weight infants (8 cases of premature infants) and 43 cases of their mothers at delivery. Serum immunoglobulin and complement levels were measured by the single radial immuno diffusion method (NISSUI, Japan). The...
Lipid Composition of Serum HDL and Fatty Acid Composition of Serum Cholesteryl Esters in Newborn.
Jung Hee Kim, Dong Wook Kim, Dae Deok Ahn, Jung Kwon Lee, Yoon Ja Kim, Jung Chull Kim, Tai Ho Chung
Clin Exp Pediatr. 1985;28(12):1190-1195.   Published online December 31, 1985
Lipid consumption in early life has been implicated with atherosclerosis in later life. It has been also claimed that lipids contents of serum in early life would reflect coronary atherosclerosis in later life. Present study has undertaken to look for the composition of serum HDL and fatty acid composition of serum cholesteryl esters in newborns. Levels of high density lipoprotein...
A study on Glucose Metabolism in Newborn Infants.
Keun Chul Myung, Chang Soo Ra
Clin Exp Pediatr. 1985;28(12):1167-1176.   Published online December 31, 1985
Glucose metabolism in newborn infants has not been clearly defined. A thorough understanding of the physiology of glucose metabolism between mother and newborn infants is necessary in the evaluation of the newborn infant with hypoglycemia. Author studied the serum glucose, insulin, cyclic AMP and glucagon levels in 27 pairs of cord blood in newborn infant and maternal blood at paturition....
A Study on Calcium Metabolism in Newborn Infants.
Jin Heon Kim, Chang Soo Ra
Clin Exp Pediatr. 1985;28(10):967-976.   Published online October 31, 1985
A thorough understanding of calcium homeostasis and metabolism in newborn infants is necessary in the evaluation of any newborn infant with hypocalcemia. Author studied the levels of urinary calcium and phosphorus during the 48 hours after birth, and also studied before and after feeding during the 24 hours after birth in 19 normal term infants. And serum calcium, phosphorus, parathormone,...
A Study on Serum Creatinine and BUN Levels in Newborn Infants.
Shin Chung Jee, Chang Soo Ra
Clin Exp Pediatr. 1985;28(8):741-750.   Published online August 31, 1985
The concept of renal function in the neonate has been that the developing kidney is immature and that glomerular and tubular functions are low for body size as compared with the adult. Authors determined the serum creatinine and blood urea nitrogen (BUN) levels of cord blood in 57 newborn infants(42 normal full-term and 15 premature infants) with gestational age of...