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Volume 42(5); May 1999
Clinical Lecture
Growth and Developmental Assessment during Childhood
Clinical Practice Committee
J Korean Pediatr Soc. 1999;42(5):595-613.   Published online May 15, 1999
Original Articles
A Survey of Breast-Feeding in Jeon-ju City Area
Kyoung Bae Park, Byoung Rae Oh, Young Taek Jang
J Korean Pediatr Soc. 1999;42(5):614-620.   Published online May 15, 1999
Purpose : While the rate of breast-feeding has been rising recently in many countries, it has been gradually falling in Korea. Accordingly, we took a survey in Jeon-ju to discover the actual state of breast-feeding and find a solution. Methods : Eight hundred and sixty-four questionnaires of filled out by mothers who visited the seven local pediatric clinics and the clinic...
Cell Proliferation and Apoptosis in Heart of Trisomy 16 in Mice
Eun Jung Bae, Yong Soo Yun, Jung Sun Kim, Jeong-Wook Seo
J Korean Pediatr Soc. 1999;42(5):621-630.   Published online May 15, 1999
Purpose : Although abnormal developments of cushion and atrioventricular septum have been suggested, the exact mechanism for the development of atrioventricular septal defect is not well known. We aimed to identify the role of cell proliferation and apoptosis on cardiac morphogenesis in trisomy 16 mice(an animal model for Down's syndrome in human). Methods : We examined the difference in cardiac...
Balloon Valvuloplasty of Pulmonary Stenosis in Patients Younger than 6 Months of Age
Yang Park, Do Jun Cho, Woo Sub Sim, In Seung Park, Eun Jung Bae, Seong Ho Kim
J Korean Pediatr Soc. 1999;42(5):631-636.   Published online May 15, 1999
Purpose : Balloon valvuloplasty(BVP) is the treatment of choice for valvular pulmonary stenosis (PS). However, this procedure was usually performed in children older than 2 years. The purpose of the present study was to assess the safety and efficacy of BVP in young infants. Methods : Retrospective analysis of the medical records of 25 infants younger than 6 months of age...
Neonatal Cord Blood Leptin : Its Relationship to Birth Weight
Byung Churl Lee, In Kyung Sung, Byung Kyu Suh, Moon Young Song
J Korean Pediatr Soc. 1999;42(5):637-643.   Published online May 15, 1999
Purpose : The purpose of this study was to correlate birth weight, skinfold thickness, gestational age, BMI and ponderal index of neonates and maternal status with cord serum leptin concentration. Methods : Sixty newborns were enrolled in this study. Standard growth curves were used to categorize infants as appropriate(AGA), large(LGA), or small for gestational age(SGA). Gestational age, birth weight, length, skinfold...
Pulmonary Inflammatory Cells in Preterm Infants with Respiratory Distress Syndrome Followed by Surfactant Treatment
Hyeon-Soo Lee, Myung-Seo Kang
J Korean Pediatr Soc. 1999;42(5):644-649.   Published online May 15, 1999
Purpose : The effect of surfactant treatment on inflammatory cell populations has not been determined. I evaluated the effect of surfactant treatment on a number and distribution of inflammatory cells in bronchoalveolar lavage fluid(BALF) from the preterm infants who were dependent on mechanical ventilation over the 1st week of life. Methods : This study included 8 preterm infants with respiratory distress...
Study of the Analgesic Effect of Sucrose and Non-sucrose Sweet Substances(Aspartam, Dextrose) in Full Term Neonates
Doo San Kim, Myung Ho O, Jay Geon Sim, Kee Hyuck Kim, Min Hee Kim
J Korean Pediatr Soc. 1999;42(5):650-656.   Published online May 15, 1999
Pain Reduction Effects of Continuous Fentanyl Infusion to Intensive Care Neonates
Wi Kyung Hwang, Heng Mi Kim
J Korean Pediatr Soc. 1999;42(5):657-665.   Published online May 15, 1999
Purpose : To determine whether pain control using fentanyl would effectively reduce behavioral distress, physiologic and hormonal responses to postoperative pain and mechanical ventilation in neonates. Methods : Neonates who were admitted to the NICU(neonate intensive care unit) of Kyungpook University Hospital, requiring surgery or mechanical ventilation were evaluated. Twelve neonates undergoing operation were randomised into two groups. After operation, one...
Intralipid Infusions Effect on Nutrophil Elastase Level in Newborns
Sue Jeen Min, Yong Woon Baek, Yong Woon Baek, Yong Woon Baek
J Korean Pediatr Soc. 1999;42(5):666-671.   Published online May 15, 1999
Purpose : Parenteral nutrition is given to infants who tempararily cannot take oral feeding adequately. A lipid emulsion is added to the parenteral to supply essential fatty acids. In neonatal sepsis, elastase from azuropilic granules of the neutrophils is released and rapidly bound to α1- Proteinase Inhibitor(α1-PI). The lipid emulsion has been noted to markedly inhibit chemotaxis of neutrophils, so...
Clinical Significance of Serum ECP in Mycoplasma Pneumoniae Pneumonia
Young Ghil Rah, Dong Keun Lee, In Seok Lim, Eung Sang Choi, Soo Ahn Chae
J Korean Pediatr Soc. 1999;42(5):672-678.   Published online May 15, 1999
Purpose : Allergic inflammation of the lower respiratory tract is a characteristic clinical feature in asthma patients, in which eosinophils play an important role. The activity of eosinophil may be determined by measuring the level of eosinophil cationic protein(ECP) in sputum or serum as a potential marker of the inflammatory severity. Methods : We measured the serum concentrations of ECP...
Age-Related Criteria for Signal-Averaged Electrocardiographic Late Potentials in Children
Heon-Seok Han, Ki-Moon Cha
J Korean Pediatr Soc. 1999;42(5):679-685.   Published online May 15, 1999
Purpose : Ventricular late potentials have been shown to predict malignant ventricular arrhythmia and sudden cardiac death in patients with myocardial infarction and cardiomyopathy. Low amplitude and high frequency potentials at the end of the QRS complex can be detected on the body surface using signal-averaged electrocardiogram(SAECG). This study determines the age-related criteria of SAECG parameters and age-related differences. Methods :...
Effects of Thioredoxin on Oxidative Neuronal Cell Injury
Hyunmi Kim, Gyoung Hee Kim, Yoon Song Lee
J Korean Pediatr Soc. 1999;42(5):686-696.   Published online May 15, 1999
Purpose : Thioredoxin is an endogenous antioxidant which directly scavenges reactive oxygen species(ROS) and regenerates oxidatively damaged protein by reducing potential at the redox active disulfide(-Cys-Gly-Pro-Cys-) site. Under oxidative stress, thiredoxin plays a protective and adaptative role by inducing expressions. The aim of this study was to clarify the role of thioredoxin on oxidative neuronal cell injury. We investigated the...
Gastrointestinal Disease in Children with Iron Deficiency Anemia
Yong Joo Kim, Sung Kyun Park, Ho Joon Lim, Hahang Lee
J Korean Pediatr Soc. 1999;42(5):697-703.   Published online May 15, 1999
Purpose : The authors performed this study to find out the associated GI disease and H. pylori infection in children with iron-deficiency anemia(IDA). Methods : Twenty-six children older than 2 years with IDA and no history of insufficient iron intake were investigated from 1994 to 1998. Gastrofiberoscopic examination and biopsy and rapid urease test were performed with serum H. pylori IgG....
Study on Changes in Bone Metabolism with Growth Hormone Treatment in Children with Growth Hormone Deficiency - Changes in the Serum Levels of Bone Markers -
Eun Young Kim, Sei Won Yang
J Korean Pediatr Soc. 1999;42(5):704-710.   Published online May 15, 1999
Case Reports
A Case of Idiopathic Hypoparathyroidism Associated with Graves' Disease
Eun Young Jang, Hwang Min Kim, Baek Keun Lim, Jong Soo Kim
J Korean Pediatr Soc. 1999;42(5):716-721.   Published online May 15, 1999
Graves' disease is a relatively rare endocrinologic disorder in childhood age and often associated with other endocrinologic disorders such as type I diabetes mellitus and Addison's disease etc. Also, it is associtated with non-endocrinologic autoimmune diseases such as systemic lupus erythematosus, myasthenia gravis, idiopathic thrombocytopenic purpura, vitiligo and pernicious anemia. However, idiopathic hypoparathyroidism associated with Graves' disease is very...
A Case of Hinman Syndrome Successfully Treated by Non-Surgical Measures
Won Seoung Lee, Chang Weon Oh, Ki Bok Kim
J Korean Pediatr Soc. 1999;42(5):722-727.   Published online May 15, 1999
Hinman syndrome is a condition caused by an incoordination between the detrusor and external urethral sphincter during bladder contraction. Manifestations include day-and-night wetting, residual urine, infected urine, vesicoureteral reflux, christmas-tree shaped bladder-wall change, and upper tract damage without neurologic lesion or anatomical obstruction. Recently, this incoordination was postulated to be due to over-compensation of the external sphincter which compensates the...
A Case of freeman-Sheldon Syndrome in Father and Son
Young Seok Cho, Eun Young Jang, Byung Ho Cha, Back Keun Lim, Jong Soo Kim
J Korean Pediatr Soc. 1999;42(5):728-732.   Published online May 15, 1999
A Case of Idiopathic Chylothorax Treated with Pleuroperitoneal Shunt
Sung Ho Jung, Dong Un Kim, Yoon Kyung Lee, Byung Joon Choi, Jin Tack Kim, Ik Jun Lee
J Korean Pediatr Soc. 1999;42(5):733-737.   Published online May 15, 1999
Chylothorax is an accumulation of lymphatic fluid or chyle in the pleurual cavity resulting from a leak of the thoracic duct or one of its major divisions. If the loss of chyle persist, life threatening nutritional and immunologic deficiencies ensue. Initial conservative managements consist of tube thoracostomy drainage and dietary modification(low fat diet and total parenteral nutrition). In some refarctory...