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Volume 42(4); Apr 1999
Clinical Lecture
Treatment of Symptoms Related to Common Cold in Children
Ki Young Lee
J Korean Pediatr Soc. 1999;42(4):449-461.   Published online April 15, 1999
Original Articles
Fcr Receptor and Mac-1 Expression and Functional Differentiation of HL-60 Cells by All-trans Retinoic Acid
Hae Soon Kim, Kyung Hyo Kim, Gyoung Hee Kim, Ju Young Seoh,
J Korean Pediatr Soc. 1999;42(4):462-471.   Published online April 15, 1999
Purpose : During differentiation of HL-60 cells by all-trans retinoic acid(ATRA), we analyzed the expression of Fcr receptors and Mac-1 by molecules of equivalent soluble fluorochromes(MESF) and functional studies. Methods : HL-60 cells were induced to differentiate by adding 1μM ATRA. On the 4th and 7th day after stimulation as well as before stimulation, the cells were analyzed for phenotypic and...
Clinical Trial of Domestically Developed Bovine Lung Surfactant YY-38 in Neonatal Respiratory Distress Syndrome
Chul Lee, Jeong Nyun Kim, Min-Soo Park, Moon Sung Park, Shin Won Yoon, Wook Chang, Ran Namgung, Kook In Park, Dong-Gwan Han
J Korean Pediatr Soc. 1999;42(4):472-483.   Published online April 15, 1999
Purpose : We previously reported modified bovine lung surfactant YY-38(NewfactanⓇ) had a low surface tension, good hysteresis, and exhibited good pressure-volume curve in animal experiment (J Korean Pediatr Asso 1997;40:771-85). We performed multicenter clinical trial of NewfactanⓇ in neonatal RDS. Methods : Seventy-seven infants with RDS(GA 31.8¡¾2.9 wks and BW 1,809¡¾592 gm) in 4 NICU were enrolled. After administration of...
Rehospitalization of Low-birth-weight Infants Who Were Discharged from NICU
Kyung Dan Choi, Young Suk Chae, Oh Kyung Lee
J Korean Pediatr Soc. 1999;42(4):484-490.   Published online April 15, 1999
Purpose : We tried to compare normal term infants with low-birth-weight infants discharged from NICU by evaluating morbidity. So we studied rates of rehospitalization, reasons for rehospitalization and neonatal risk factors that affect rehospitalization of normal term infants and low-birth-weight infants discharged from NICU. Methods : This study was performed on 217 low-birth-weight infants discharged from NICU and 126 normal term...
Positivity of cagA and vacA Genes of Helicobacter pylori by PCR Assay of Gastric Biopsy Specimens and Gastric Inflammation in Children
Jeong Wan Seo, Mi Ae Lee, Woon Sup Ha
J Korean Pediatr Soc. 1999;42(4):491-500.   Published online April 15, 1999
Purpose : The aim of the present study is to detect cagA and vacA genes of Helicobacter pylori(H. pylori) strain in gastric biopsy specimens and to evaluate its association with gastric inflammation in children. Methods : The cagA and vacA genes were detected by a direct polymerase chain reaction(PCR) assay of gastric biopsy specimens in 22 patients who were...
Prevalence and Identification of Rotaviruses in Stool Specimens of Patients with Acute Diarrhea from Several Regions of Korea
Dong Soo Kim, Beom Soo Park, Dong Hyuk Jung, Jae Moon Ahn, Chul Joong Kim, Shien Young Kang
J Korean Pediatr Soc. 1999;42(4):501-509.   Published online April 15, 1999
Purposes : Rotaviruses are the main cause of infantile diarrheal diseases worldwide. The purpose of this study is to obtain epidemiologic data of rotavirus infections in Korea. Methods : Stool specimens were collected from 150 patients with acute diarrheal symptoms, who were admitted to Yonsei Medical Center and Chungbuk National University Hospital. After isolating the virus from the specimens, the viruses...
Effect of Low-Dose Aspirin Therapy on Platelet Aggregation in Kawasaki Disease
Ju Yeon Yeo, Heon Eui Le, Young Mi Hong, Ki Sook Hong, Wha Soon Chung
J Korean Pediatr Soc. 1999;42(4):510-518.   Published online April 15, 1999
Purpose : Aspirin(acetylsalicylic acid) has been used to treat unstable angina and acute myocardial infarction in adults and Kawasaki disease in children. The antithrombotic effect of aspirin was attributed to its ability to inhibit platelet aggregation by inhibiting platelet cyclooxygenase, which leads to decreased thromboxane synthesis. The purpose of this study was to evaluate the effect on the platelet aggregation...
Clinical Observations of Coarctation of the Aorta
Hui Jung Cho, Chang Ho Ha, Dong Seok Lee, Myung Chul Hyun, Sang Bum Lee
J Korean Pediatr Soc. 1999;42(4):519-525.   Published online April 15, 1999
Purpose : Due to controveries surrounding in the incidence of coarctation of aorta which reports previously stated rare among Orientals, we evaluated clinical characteristics, natural courses of coarctation of aorta and effects of different surgical modalities. Methods : Medical records of 51 patients with coarctation of aorta, diagnosed by 2-dimensional echocardiography in Kyungpook University Hospital Pediatric Cardiac Laboratory from June 1985...
Clinical Profiles and Anatomic Classification of Intestinal Malrotation
Jung A Kim, Jae Seong Ko, Jeong Kee Seo, Kwi Won Park, Woo Sun Kim, In One Kim
J Korean Pediatr Soc. 1999;42(4):526-534.   Published online April 15, 1999
Purpose : Intestinal malrotation is a developmental anomaly and may be complicated by volvulus and intestinal necrosis. We performed anatomic classification and compared clinical profiles to understand their relationship. Methods : Twenty-eight children were diagnosed as intestinal malrotation at Seoul National University Children's Hospital between Jan. 1980 to Dec. 1995. The patients were classified into 4 groups by age at...
Congenital Esophageal Stenosis : with Special Reference to Diagnosis and Postoperative Complications
Ju Young Jang, Jae Seong Ko, Kwi Won Park, Woo Seon Kim, In Won Kim, Ja Jun Jang, Jeong Kee Seo,
J Korean Pediatr Soc. 1999;42(4):535-544.   Published online April 15, 1999
Purpose : Congenital esophageal stenosis(CES) is one of the rare causes of recurrent vomiting during infancy and childhood. We studied the diagnostic and therapeutic tools and postoperative complications for early diagnosis and adequate management of CES. Methods : Fourteen cases of CES were evaluated for clinical manifestations, findings of esophagogram and esophagoscopy, classification of pathologic findings and postoperative complications. Results : Most...
The Risk Factors of Renal Scar in Childhood Acute Pyelonephritis
Soo Ja Hwang, Seung Joo Lee
J Korean Pediatr Soc. 1999;42(4):545-552.   Published online April 15, 1999
Purpose : To observe the risk factors of renal scar in children with first acute pyelonephritis (APN) who had photopenic defects on initial 99mTc-DMSA spect renal scan. Methods : Forty-seven children with first APN(M : F=33 : 14) who were admitted to Ewha Womans University Hospital from September, 1993 to Febrary, 1998, were divided into renal scar group(N=17, Kidney unit(KU)=18) and...
Immunohistochemical Expression of c-fos Protein and Histologic Findings after Instillation of Kainic Acid in Hippocampus of Neonatal Rat Brain
Soo Ahn Chae, Yong Soo Kim, Byoung Hoon Yoo, Won Bok Lee
J Korean Pediatr Soc. 1999;42(4):553-560.   Published online April 15, 1999
Purpose : c-fos is rapidly and transiently induced in the intact CNS by a wide variety of exogenous stimuli that include seizures, glutamate receptor activation, sensory stimulation and stress. In adult animals, systemic KA administration produces limbic seizures that results in c-fos protein expression, irreversible morphological changes and localized neuronal death. So we studied the pattern of c-fos protein expression...
Usefulness of Minimal Model Analysis : Measurement of Insulin Sensitivity, Glucose Effectiveness, and Insulin Secretory Capacity from Pancreatic Islet Cells in Children with Simple Obesity or Type 2 Diabetes Mellitus
Se Young Kim, Sei Won Yang
J Korean Pediatr Soc. 1999;42(4):561-570.   Published online April 15, 1999
Purpose : It is known that insulin resistance and compensatory hyperinsulinemia from pancreatic islet cells to overcome insulin resistance could develop in children with simple obesity. When insulin resistance is aggravated by decompensation of high insulin secretion, obese children frequently progress to overt type 2 diabetes mellitus(DM). The purpose of the present study was to measure insulin sensitivity, glucose effectiveness,...
Case Reports
A Case of Ulcerative Colitis in a 3-year-old Child
Jeong Hee Kang, Hyeon Joo Lee, Jee Eun Lee, Soo Kyeong Lee, Soo Nam Lee, Yeon Ho Choi
J Korean Pediatr Soc. 1999;42(4):571-575.   Published online April 15, 1999
Ulcerative colitis is a chronic relapsing inflammatory disease localized on the colon. This disease is rare in children under 10 years of age. We experienced a case of ulcerative colitis in a 3-year- old male child. He was admitted due to fever, abdominal pain and diarrhea for 5 days, followed by rectal bleeding for 2 days. The diagnosis was established...
Levamisole-Induced Reversible Agranulocytosis in Children with Steroid Dependent Nephrotic Syndrome
Su Jin Lee, Su Ja Hwan, Eun Seon Yoo, Seung Joo Lee
J Korean Pediatr Soc. 1999;42(4):576-579.   Published online April 15, 1999
Levamisole has been used for nephrotic syndrome due to its immunostimulating, immunomodulating, and steroid-sparing effects. Agranulocytosis, a serious side effect of levamisole, was rare and mostly associated with autoimmune disease, neoplastic disease and HLA B27 except one case in a nephrotic syndrome who was treated with high-dose(5mg/kg QOD) levamisole. This 15 year-old girl with steroid dependent nephrotic syndrome, who was...
A Case of Bronchial Mucoepidermoid Carcinoma in Child
In Jeong Kim, Jin Soo Hwang, In Seok Kim, Byung Ju Kim, Jae Sook Ma
J Korean Pediatr Soc. 1999;42(4):580-583.   Published online April 15, 1999
Bronchial mucoepidermoid carcinoma is very rarely encountered in children. We report a case of bronchial mucoepidermoid carcinoma in a 10-year-old boy who presented with persistent cough and atelectasis. Bronchoscopic examination showed a tumor mass occluding the right bronchus intermedius, and the mass was removed by bronchoscopy. The results of the pathological examination revealed low-grade mucoepidermoid carcinoma. He underwent right middle...
A Case of Cavernous Sinus Thrombosis due to a Mistreated Facial Furuncle
Chae Yun Cho, Kyoung Sim Kim, Ki Bok Kim
J Korean Pediatr Soc. 1999;42(4):584-588.   Published online April 15, 1999
Infections of the face, especially of the medial third or “the danger triangle”, are the most frequent primary foci associated with thrombosis of cavernous sinus. Microorganisms entering the facial vein and pterygoid plexus from these sites are easily carried to the sinus through the ophthalmic vein. When the septic thrombosis involves various structures in the sinus, multiple clinical manifestations develop...
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