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Volume 50(5); May 2007
Review Articles
Allergic skin test
Byong Kwan Son, Dae Hyun Lim
Korean J Pediatr. 2007;50(5):409-415.   Published online May 15, 2007
Allergy skin prick test and intradermal test represent one of the major tools in the diagnosis of IgE- mediated diseases like as atopic asthma, allergic rhinitis, atopic dermatitis, food and drug allergy, and insect bite when properly performed. Skin tests are of particular importance in fields such as allergen standardization, pharmacology, and epidemiology. Even if skin tests seem easy to...
Clinical significance of serum IgE
Hai Lee Chung
Korean J Pediatr. 2007;50(5):416-421.   Published online May 15, 2007
Many previous studies have proved that human allergic disease resulted from the formation of antibodies belonging to a unique immunoglobulin isotype termed immunoglobulin E (IgE). Most of IgE- producing plasma cells are found in the lymphoid tissue associated with the gastrointestinal and respiratory tracts. IgE may be found free in the mucosal secretions of these tissues, bound to local mast...
Lung function tests in preschool children
Yong-Mean Park
Korean J Pediatr. 2007;50(5):422-429.   Published online May 15, 2007
Measurement of lung function is an integral component of respiratory physiology and of clinical assessment of lung diseases in school age children and adults. Pulmonary function test of infants and children under the age of 2 years have now been standardised and are being used both in research and as an adjunct to clinical management. By contrast, until recegntly, children...
Pathophysiology and management of disorders in water metabolism
Dong Un Kim
Korean J Pediatr. 2007;50(5):430-435.   Published online May 15, 2007
Even though we drink and excrete water without recognition, the amount and the composition of body fluid remain constant everyday. Maintenance of a normal osmolality is under the control of water balance which is regulated by vasopressin despite sodium concentration is the dominant determinant of plasma osmolality. The increased plasma osmolality (hypernatremia) can be normalized by the concentration of urine,...
Original Articles
A Clinical Study of Child Abuse
Yoon Jin Choi, Shin Mi Kim, Eun Jung Sim, Do Jun Cho, Dug Ha Kim, Ki Sik Min, Ki Yang Yoo
Korean J Pediatr. 2007;50(5):436-442.   Published online May 15, 2007

Purpose: To promote awareness and efforts by pediatricians to identity and prevent child abuse by investigation of characteristics of victim and types of injury caused by abuse. Methods: A retrospective study was performed with 20 patients who had been diagnosed or suspected as child abuse at Hallym University Hospital from January 1999 to December 2005. The medical records, radiologic documents,...
Antithrombin-III as an early prognostic factor in children with acute lung injury
Young Seung Lee, Seonguk Kim, Eun Kyeong Kang, June Dong Park
Korean J Pediatr. 2007;50(5):443-448.   Published online May 15, 2007
Purpose : To evaluate the potential prognostic value of the antithrombin-III (AT-III) level in the children with acute lung injury (ALI), we analyzed several early predictive factors of death including AT-III level at the onset of ALI and compared the relative risk of them for mortality. Methods : Over a 18-month period, a total of 198 children were admitted to our...
Antibody prsistence after Haemophilus influenzae type b (Hib) primary vaccination and response to boosters in Korean children
Hyunju Lee, So Eun Park, Soo Young Lim, Kyong Min Choi, Hoan Jong Lee, Kyung Hyo Kim
Korean J Pediatr. 2007;50(5):449-456.   Published online May 15, 2007
Purpose : Antibody persistence after primary series of Haemophilus influenzae type b (Hib) vaccine and responses to boosters are seldom studied in Korean children. We performed this study to evaluate the antibody titer in relation to booster immunization of Hib vaccine in Korean children. Method : One hundred forty four children aged 12-23 months were enrolled in three university hospitals. The...
Different characteristic between Escherichea coli and non-Escherichea coli urinary tract infection
Hee Jin Jung, Ji A Aum, Soo Jin Jung, Jae Won Huh
Korean J Pediatr. 2007;50(5):457-461.   Published online May 15, 2007
Purpose : Urinary tract infection (UTI) is a common bacterial infectious disease in childhood. Especially UTI in infant and young children is associated with urinary tract anomalies such as hydronephrosis, vesicoureteral reflux. The aim of this study was to compare the clinical and laboratory characteristics, and uroradiologic findings of UTI caused by pathogens other than E. coli with UTI caused...
The changes of electrocardiography and signal-averaged electrocardiography after surgical repair of Tetralogy of Fallot
Hye-Eun Seo, Hae-Ri Lim, Yeo-Hyang Kim, Myung-Chul Hyun, Sang-Bum Lee
Korean J Pediatr. 2007;50(5):462-468.   Published online May 15, 2007
Purpose : The purpose of this study was to analyze the changes of the late potential of Signal- averaged electrocardiography (SAECG) and Electrocardiography (ECG) parameters during follow up of those who had taken surgical repair of Tetralogy of Fallot (TOF). Methods : Nine patients who had taken surgical repair of TOF since 1985 checked SAECG and standard 12 leads ECG twice...
Closure of secundum atrial septal defect: comparison between percutaneous and surgical occlusion
Na Yeon Kim, Hyun Jung Kwon, Deok Young Choi, Mi Jin Jung, Chang Hyu Choi, Seong Ho Kim
Korean J Pediatr. 2007;50(5):469-475.   Published online May 15, 2007
Purpose : This study was performed to compare the safety, efficacy and clinical results of the Amplatzer septal occluder (ASO) for closure of secundum atrial septal defect (ASD) with surgery. Methods : One hundred fifteen patients diagnosed as isolated secundum ASD in Gil Medical Center, Gachon University of Medicine from January 2000 to July 2006 were included. Seventy patients underwent surgical...
Evaluation of short-term cardiac function by tissue Doppler imaging in pre and postoperative period of congenital heart disease
Jun-Hwa Lee, Yeo-Hyang Kim, Myung-Chul Hyun, Sang-Bum Lee
Korean J Pediatr. 2007;50(5):476-483.   Published online May 15, 2007
Purpose : The objective of this study was to assess ventricular function by tissue Doppler imaging (TDI) in children with congenital heart disease (CHD) who have been undergoing open heart surgery (OHS) using cardiopulmonary bypass. We tried to compare the parameters of tissue Doppler imaging before and after OHS in patients with congenital heart disease. Methods : This study was conducted...
Valproate-associated weight gain and potential predictors in children with epilepsy
Gook Chan Jang, Eun Young Kim, Young Il Rho, Kyung Rye Moon, Sang Kee Park
Korean J Pediatr. 2007;50(5):484-488.   Published online May 15, 2007
Purpose : The purpose of this study was to determine the incidence and potential predictors of weight gain in older children and teens treated with valproate (VPA) for epilepsy. Methods : Sixty-five subjects aged 8 to 17 years of age, who began VPA treatment between January 1, 2001, and December 31, 2004, and who had documented weight and height measurements...
Case Reports
A case of idiopathic renal hypouricemia
Moon Hee Han, Sang Uk Park, Deok-Soo Kim, Jae Won Shim, Jung Yeon Shim, Hye Lym Jung, Moon Soo Park
Korean J Pediatr. 2007;50(5):489-492.   Published online May 15, 2007
Idiopathic renal hypouricemia is a disorder characterized by impaired urate handling in the renal tubules. This disease usually produces no symptoms, but hematuria, uric acid nephrolithiasis or acute renal failure may develop. A defect in the SLC22A12 gene, which encodes the human urate transporter, is the known major cause of this disorder. We describe a 10-month-old boy with idiopathic renal...
A case of dapsone syndrome
Yoo Jong Won, Ok Lan Kim, Seung Taek Yu, Young Wook Yoon, Du Young Choi
Korean J Pediatr. 2007;50(5):493-496.   Published online May 15, 2007
Diamino-diphenyl-sulfone (Dapsone) is widely used in the treatment of leprosy and a variety of blistering skin diseases. It sometimes has adverse side effects with common usual doses, such as skin, nervous system, gastrointestinal tract, liver, kidney and hematologic toxicity. One of these side effects is a rare but serious hypersensitivity reaction called dapsone syndrome, which occurs several weeks after the...