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The clinical pictures of 44 children with IgM antibody to CMV (cytomegalovirus) by ELISA(enzyme linked immunosorbent assay) were reviewed retrospectively, and the significance of serum CMV specific IgM antibody and virus isolation in the urine was analyzed. Age of the patients with IgM antibody to CMV ranged from 23 days to 8 years 7 months, and median age was 2 months.... |
We have previously reported several methods of in vitro immunization using different conditioned media, and the highest antibody titer was observed when a mixture of three conditioned media[PHA-stimulated adherent splenocytes conditioned medium (ASM-P), ASM-p-stimulated non-adherent splenocyte conditioned medium (NASM-A), ASM-P-stimulated thymocyte conditioned medium (TM-A)] was used. In this experiment, thymocytes and/or bone marrow cells was added instead of above conditioned media... |
We reviewed the medical records of 14 children (8 girls, 6 boys), diagnosed as hemolytic uremic syndrome at Seoul National University Children뭩 Hospital from 1981 to 1990. The age at presentation ranged from 1 month to 10 years, with a mean age of 2.7 years. Only eight (57.1%) of the children had diarrheal prodrome and five (35.7%) had grossly bloody... |
Total Nutrient Admixture(TNA) is an intravenous nutrient system composed of dextrose, amino acid, fat, electrolytes, vitamins and trace elements in a single container which is administered over 24 hours. Twenty six seriously ill or premature neonatal patients reciving parenteral nutrition with TNA were studied by analyzing anthropometric parameters, laboratory values, and complications. The objective of the study was to test the... |
From September 1982 to July 1991, 40 infants and children aged 3 days to 13 years(mean 3.1 years) underwent implantation of 45 cardiac pacemakers using epicardial leads(40 primary implants, 5 re-implants). Nineteen patients required pacing for surgically acquired heart block, 1 for surgically acquired sinus node dysfunction, 11 for congenital complete atrio-ventricular(AV) block, 7 for nonsurgical sinus node dysfunction, and... |
When we are examining a cardiac patient, we want to make a physical diagnosis including involved ventricles, type of overload(volume or pressure), its degree, and the status or degree of pulmonary hypertension. Among various physical examinations of the cardiac patients, a left parasternal movement can give us a status of various degree of the volume and pressure overload of the ventricles.... |
A clinical study was made on 533 patients with cardiovascular disease who were admitted to pediatric department of Chonbuk National University Hospital and performed cardiac catheterization and cineangiography from February 1984 to August 1991. The results were as follows; 1) The ratio of male to female was about 0.81:1; among 533 cases, male 283cases, male 283cases, female 295cases. 2)The age distribution of the... |
Exercise and allergen challenges are the main tools to investigate the bronchial responsiveness in experimentally provoked asthma. It is recognized that LAR, which often follows early asthmatic response(EAR) by 3 to 10 hours after challenge, is more closely related to the basic pathogenetic mechanisms operating in bronchial asthma. Although exercise induces an EAR within the first hour similar to allergen... |
Hutchinson-Gilford Progeria Syndrome is an extremely rare condition that was initially reported by Jonathan Hutchinson in 1886 and further described by Hastings Gilford in 1904. Clinical manifestations are evident by the first or second year of life with the physical characteris-tics of the elderly. Progeric patients ordinarily develop atherosclerosis and die of cardiac or cerebral vascular disease between 7 and 27... |
The Prune belly syndrome is a rare congenital anomaly characterized by lax, wrinkled abdominal wall, cryptorchidism and urinary tract anomalies. But it has a wide spectrum of clinical presentation and combine with other anomalies such as pulmonary, skeletal, digestive, cardiovascular and other system. We experienced a case of prune-belly syndrome associated with Turner syndrome in a 18 month old female... |
Pseudohypoaldosteronism(PHA) is rare salt losing disease which is characterized by mineralcorticoid unresponsiveness of the end organ. Severe hyponatremia and hyperkalemia are present despite high plasma aldosterone. We experienced a case of PHA in a 40-days old male infant who was presented with anorexia, vomiting and lethargy for several days. Labortory data showed hyponatremia, hyperkalemia and metabolic acidosis. Renal function was normal... |
A 14-year-old Korean boy with Addison's disease probably of tuberculosis origin is presented with a brief review of the literature. The patient was admitted to our hospital on July, 23th, 1990, because of dark brown pigmentation of the skin, mucous membrane and nail beds. On physical examination, he was moderately developed, relatively poorly nourished. Skin and mucous membranes were diffusely dark brown,... |
Anomalous origin of the pulmonary artery from the ascending aorta is a rare congenital cardiovascular anomaly which usually involves the right pulmonary artery. Because congestive heart failure and the pulmonary vascular obstructive changes develop early in life, early diagnosis and surgical correction are essential. We experienced two cases of anomalous origin of the right pulmonry artery from the ascending aorta; aorticopulmonary septal... |
Cor triatriatum is characterized by the presence in the left atrium of a perforated muscular membrane which separates the atrium into proximal and distal chambers. Authors experienced a case of cor triatriatum in a 20 month old boy. Diagnostic confirmation was made by 2-D echocardiography, cardiac catheterization completely excised. The postoperatative course was excellent. |
Primary hyperparathyroidism is very rare and often fatal disease in childhood. We experienced a case in which a 4 months old male patient complaning of lethargy, hypotonia, respiratory difficulty showed typical laboratory and radiological findings compatible to primary hyperparathyroidism. He was successfully treated with total parathyroidectoimy with partial parathyroid autotrans-plantation. Thus the case of primary hyperparathyroidism in infancy is presented with... |
A female infant at 38 days of age was admitted to pediatric department of Pusan National University hospital due to dehydration, weight loss, vomiting, polyuria. Physical exmination at the time of admission revealed a slightly anemic, moderately dehydrated, dwarfed female infant in no acute distress. Laboratory studies on admission revealed hypokalemic, hyperchloremic metablic acidosis with normal anion gap and persistent... |
Acute disseminated encephalomyelitis(ADEM) is an acute inflammatory demyelinating disease of the central nervous system. We experienced a case of ADEM in an 8 year-old boy who showed headache, vomiting, weakness of lower extremities and visual disturbance. Brain magnetic resonance imaging demonstrated multiple patch high signal intensity in both optic nerves, both thalamus, splenium of corpus callosum, and subcortical white matter... |