- Original Article
- Neurology
- Efficacy and tolerability of adjunctive perampanel treatment in children under 12 years of age with refractory epilepsy
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Yuni Yun, Dongsub Kim, Yun-Jeong Lee, Soonhak Kwon, Su-Kyeong Hwang
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Clin Exp Pediatr. 2019;62(7):269-273. Published online December 26, 2018
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Purpose: There is limited data on the use of perampanel in children under 12 years of age. We evaluated the efficacy and tolerability of adjunctive perampanel treatment in children under 12 years of age with refractory epilepsy.
Methods: This retrospective observational study was performed in Kyungpook National University Hospital from July 2016 to March 2018. A responder was defined as a... |
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- Clinical importance of F-waves as a prognostic factor in Guillain-Barré syndrome in children
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Eung-Bin Lee, Yun Young Lee, Jae Min Lee, Su Min Son, Su-Kyeong Hwang, Soonhak Kwon, Sae Yoon Kim
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Clin Exp Pediatr. 2016;59(6):271-275. Published online June 30, 2016
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Purpose A limited number of studies have examined the link between F-wave abnormalities and clinical presentation in pediatric Guillain-Barré syndrome (GBS). Therefore, this study examined the importance of F-wave abnormalities as a prognostic factor in pediatric GBS patients. MethodsThe records and electrodiagnostic studies (EDS) of 70 GBS patients were retrospectively evaluated, and divided into 2 groups according to the results of EDS.... |
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- Review Article
- Early-onset epileptic encephalopathies and the diagnostic approach to underlying causes
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Su-Kyeong Hwang, Soonhak Kwon
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Clin Exp Pediatr. 2015;58(11):407-414. Published online November 22, 2015
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Early-onset epileptic encephalopathies are one of the most severe early onset epilepsies that can lead to progressive psychomotor impairment. These syndromes result from identifiable primary causes, such as structural, neurodegenerative, metabolic, or genetic defects, and an increasing number of novel genetic causes continue to be uncovered. A typical diagnostic approach includes documentation of anamnesis, determination of seizure semiology, electroencephalography, and... |
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- Cognitive and other neuropsychological profiles in children with newly diagnosed benign rolandic epilepsy
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Soonhak Kwon, Hye-Eun Seo, Su Kyeong Hwang
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Clin Exp Pediatr. 2012;55(10):383-387. Published online October 29, 2012
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Purpose Although benign rolandic epilepsy (BRE) is a benign condition, it may be associated with a spectrum of behavioral, psychiatric, and cognitive disorders. This study aimed to assess the cognitive and other neuropsychological profiles of children with BRE. MethodsIn total, 23 children with BRE were consecutively recruited. All children underwent sleep electroencephalography (EEG) and were assessed on a battery of comprehensive neuropsychological... |
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- Clinical experience with amitriptyline for management of children with cyclic vomiting syndrome
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Ye Jee Shim, Jung-mi Kim, Soonhak Kwon, Byung-Ho Choe
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Clin Exp Pediatr. 2009;52(5):538-543. Published online May 15, 2009
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Purpose : To report the clinical experience with amitriptyline for managing children with cyclic vomiting syndrome (CVS).
Methods : Totally, eleven children (eight males) were diagnosed with CVS. Of these, medical records were reviewed for eight children treated with amitriptyline; three children were not treated because one was not followed up and two were kept under observation to study the... |
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- Clinical Lecture
- Neurological Examination after the Newborn Period until 3 Years of Age
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Soonhak Kwon
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Clin Exp Pediatr. 2004;47(11):1142-1148. Published online November 15, 2004
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The children should not be regarded as miniature adults since they are in the dynamic process of growth and development. Among many pediatric problems, the developmental delay may be central to them. For this reason, primary care physicians, especially pediatricians should be able to manage children with probable developmental delays because early detection and treatment of developmental delay or neurological... |
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- Case Report
- A Case of Ornithine Transcarbamylase(OTC) Deficiency
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Soonhak Kwon, Yejhin Lee, Byung-Ho Choe, Sangkwon Lee
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Clin Exp Pediatr. 2000;43(1):123-127. Published online January 15, 2000
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OTC deficiency is an X-linked disorder in which the synthesis of urea is impaired. OTC catalyzes the synthesis of citrulline from carbamyl phosphate and ornithine. Complete or partial deficiencies of this enzyme may lead to Reye syndrome like picture such as encephalopathy, hepatic dysfunction, hyperammonemia, etc. We recently had a case that was presented as recurrent Reye syndrome, and was... |
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