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This experiment was carried out to investigate the morphological changes of cardiac tissue in
Adriamycin treated rats.
Adriamycin was administered (2.5 mg/kg/wk) for 5 weeks, subcutaneously. Cardiac tissue stained
by H-E and Trichrom’s method.
Clinical findings of congestive heart failure were also observed during experiment.
The results were as follows ；
1) Symptoms and signs of congestive heart failure (tachypnea, ascites, hepatomegaly) were
appeared in 43% (6 out... |
