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Original Article
Predictable risk factors and clinical courses for prolonged transient tachypnea of the newborn
Ji Young Chang, Chang Ryul Kim, Ellen A Kim, Ki Soo Kim
Clin Exp Pediatr. 2010;53(3):349-357.   Published online March 15, 2010
Purpose : Transient tachypnea of the newborn (TTN) is usually benign and improves within 72 hours. However, it can also progress to prolonged tachypnea over 72 hours, profound hypoxemia, respiratory failure, and even death. The aim of this study is to find predictable risk factors and describe the clinical courses and outcomes of prolonged TTN (PTTN). Methods : The medical records...
Outcome of pregnant mothers with systemic lupus erythematosus(focusing on congenital heart block)
Hey Sung Baek, Jae Hyung Choi, Nam Su Kim, Chang Ryul Kim, Su Ji Moon
Clin Exp Pediatr. 2006;49(4):381-387.   Published online April 15, 2006
Purpose : Neonatal lupus is characterized by congenital complete heart block(CCHB), cutaneous rash, and laboratory abnormalities in infants born to mothers with systemic lupus erythematosus(SLE). This study aims to examine the incidence of CCHB and clinical outcome in neonates born to mothers with SLE. Methods : The study group consisted of 49 neonates, born from 57 pregnancies of 55 women with...
DNA Methylation Change of IL-4 Gene from T Cell in Allergic Children
Jae Won Oh, Myung Gul Yum, Chang Ryul Kim, In-Joon Seol, Su A Shin, Ha Baik Lee, Se Jin Jang
Clin Exp Pediatr. 2005;48(6):634-639.   Published online June 15, 2005
Purpose : An understanding of the immunological process is required if primary prevention of atopic diseases is to be developed in early childhood. But, it is too hard to distinguish atopy from nonatopy under the age of two clinically, because the expression of phenotype and cytokines is vague in early childhood. We evaluated DNA methylation changes at Th2 interleukin-4 gene...
A Comparative Study of the Effects of Intravenous Indomethacin and Oral Mefenamic Acid in the Treatment of Premature Infants with Patent Ductus Arteriosus
Hae Jung Park, Yoon Suk Jung, Nam Soo Kim, Chang Ryul Kim, Hyuk Kim, Soo Jee Moon
Clin Exp Pediatr. 2001;44(1):32-39.   Published online January 15, 2001
Purpose : For the management of patent ductus arteriosus(PDA) in premature infants, fluid restriction, correction of anemia, mechanical ventilation, diuretics, and surgery have been used, and the closure rate of PDA has improved significantly since the introduction of indomethacin and mefenamic acid as pharmacologic treatments of PDA. We studied to evaluate and compare the therapeutic effects of indomethacin and mefenamic...
Outcome in Infants of Mothers with Systemic Lupus Erythematosus
Chang Ryul Kim, Young Pyo Chang, Hee Seop Kim, Mi Jung Kim, Byung Il Kim, Jung-Hwan Choi, Chong Ku Yun, Bo Hyun Yoon, Hee Chul Syn, Syng Wook Kim, Seon Yang Park, Hahng Lee
Clin Exp Pediatr. 1993;36(6):791-804.   Published online June 15, 1993
A large proportion of patients with systemic lupus erythematosus(SLE) are women of reproductive age. Their fetal outcome is undoubtedly less favourable than in haelthy women. Although there is no evidence of an increase in congenital anomalies, increased frequencies of miscarriage, stillbirth, growth retardation, and preterm delivery are recognized It mainly depends on the compromise of uteroplacental circulation such as renal...
A Clinical Study of Hospitalized Neonates with Fever.
Youn Mo Ahn, Chang Ryul Kim, Woo Gill Lee, Soo Jee Moon
Clin Exp Pediatr. 1988;31(11):1437-1444.   Published online November 30, 1988
Life-threatening bacterial infections such as meningitis, septicemia, and pneumonia in the neonates are more common than at any other time in life and signs of these infections are often subtle and non-specific. Because of these factors, the patient who has persistent fever will almost always be started on parenteral antibiotics immediately following evaluation. On the other hand there is also evidence that the hospital...
Clinical Value of Urinary β₂ -Microglobulin in Patients with Urianry Tract Infection.
Nak Uk Sung, Chang Ryul Kim, Jeh Hoon Shin, Woo Gill Lee
Clin Exp Pediatr. 1987;30(9):1014-1020.   Published online September 30, 1987
Urinary tract infection (UTI) in children is relatively common infectious disease and it may be the forerunner of severe renal diseases in adulthood. The site of infection is an important factor in the evaluation of the clinical course, treatment and prognosis of patients with UTI, because patients with bacteriuria of renal origin (pyelonephritis) are probably at risk of developing the renal parenchymal reduction seen...