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Case Report
A Case of Primary Small Cell Bronchogenic Carcinoma Detected by Bronchoscopy in a Child
Seon Ju Song, Chang Keun Kim, Churl Young Chung
Clin Exp Pediatr. 1999;42(11):1599-1603.   Published online November 15, 1999
While the frequency of primary carcinoma of the lung has recently increased in adults, it is rare in the pediatric age group. The various adult types of bronchogenic carcinoma such as squamous cell, small cell, large cell, and adenocarcinoma, are extremely rare in children. Twenty to 30 cases of primary bronchogenic carcinoma of the lung in children under 15 years...
A Case of Toxic Epidermal Necrolysis in Early Infancy
Min Seong Kim, Jeong Nyun Kim, Bang Soon Kim, Hong Joo Kim, Myung Jae Chey, Churl Young Chung
Clin Exp Pediatr. 1999;42(11):1594-1598.   Published online November 15, 1999
Toxic epidermal necrolysis(TEN) is a bullous disorder affecting mainly basal layers of epidermis by hypersensitive reaction. It is rarely reported in infants under six months of age. It can be developed by drug, infection, and vaccination, which makes it difficult to differentiate from staphylococcal scalded skin syndrome(SSSS) especially in early infancy. We report a case of TEN in a 6-week-old...
Original Article
Usefulness of the Flexible Bronchoscopy for Pediatric Respiratory Diseases
Chang Keun Kim, Churl Young Chung
Clin Exp Pediatr. 1999;42(6):783-789.   Published online June 15, 1999
Purpose : Flexible bronchoscopy is an important diagnostic and sometimes therapeutic tool that can be used on infants and children using light sedation and local anaesthesia. The purpose of this study is to evaluate the contribution of the flexible bronchoscopy to clinical diagnosis and therapy in children. Methods : We examined the first 100 consecutive flexible bronchoscopies performed in children under...
The Usefulness of Serum Total IgE Test by Multiple Allergosorbent Test-Chemiluminescent Assay(MAST-CLA) : Comparison with Paper Radioimmunosorbent Test(PRIST)
Hyun Chul Lee, Chang Keun Kim, Churl Young Chung
Clin Exp Pediatr. 1999;42(3):397-402.   Published online March 15, 1999
Purpose : Multiple allergosorbent test-chemiluminescent assay(MAST-CLA) is a semiquantitative method for detecting total IgE and specific IgE in serum. The purposes of this study are to investigate the correlation between MAST-CLA and Paper radioimmunosorbent test(PRIST), and to find out whether MAST-CLA can replace PRIST in measuring of serum total IgE. Methods : Data of 162 subjects were analyzed by linear...
Case Report
A Case of Allergic Bronchopulmonary Aspergillosis During Childhood
Kyoung Ah Ha, Chang Keun Kim, Churl Young Chung, Jung Sook Kim
Clin Exp Pediatr. 1999;42(2):284-288.   Published online February 15, 1999
Allergic bronchopulmonary aspergillosis(ABPA) is an inflammatory disease which causes a hypersensitivity to Aspergillus spores growing in the bronchi. The clinical syndrome is characterized by asthma, recurrent pulmonary infiltrations or mucoid impaction, eosinophilia, and central bronchiectasis. A 12-year-old boy was admitted to our hospital because of right lower chest pain and cystic mass-like shadows on a chest X-ray film. He had...
A Case of Successful Management of Hypertrophic Pyloric Stenosis with Endoscopic Balloon Dilatation
Cheol Ho Chang, Churl Young Chung
Clin Exp Pediatr. 1999;42(1):143-147.   Published online January 15, 1999
Endoscopic balloon dilatation has provided a non-operative means of managing obstructive lesions in the gastrointestinal tract. In an infant with idiopathic hypertrophic pyloric stenosis(IHPS), the stenosis was successfully dilated with endoscopic balloon dilatation. Endoscopic balloon dilatation was performed using a 9mm endoscope and through-the-scope(TTS) balloon catheter (diameter 10 to 12mm). Dilatation was performed two times for 5 minutes. The 9mm...
Original Article
Clinical Features and Endoscopic Findings of Helicobacter pylori Infection in Children
Seon Hee Kim, Cheol Ho Chang, Churl Young Chung
Clin Exp Pediatr. 1998;41(10):1359-1364.   Published online October 15, 1998
Purpose : Helicobacter pylori(H. pylori) is recognized as the cause of primary or unexplained gastrointestinal diseases in children as well as in adults. However, it is unclear whether H. pylori causes specific clinical symptoms or diseases. Therefore, we studied the clinical manifestations associated with H. pylori infection in consecutive symptomatic children undergoing diagnostic endoscopy. Methods : This study included 42...
Serum Leptin Levels in Obese Children
Kyoung Ah Ha, Il Ran Kim, Mi Jung Park, Jae Heon Kang, Churl Young Chung
Clin Exp Pediatr. 1998;41(7):953-959.   Published online July 15, 1998
Purpose : Leptin is a protein encoded by the ob gene that is expressed in adipocytes. It regulates eating behavior by the action to the satiety centers in the hypothalamus. In ob/ob mouse, adipocytes can not produce leptin because of a mutation in the ob gene which results in obesity. Whereas, leptin concentrations were elevated in obese adults, and leptin...
Case Report
Fatal Doudenal Ulcer Bleeding in Status Asthmaticus Treated with Theophylline and Steroids
Sang Woo Lee, Chang Keun Kim, Churl Young Chung, Young Doug Kim
Clin Exp Pediatr. 1998;41(4):548-552.   Published online April 15, 1998
It is generally agreed that theophylline preparations and steroids should be given intravenously for status asthmaticus. Theophylline can potentially have adverse gastrointestinal effects including abdominal pain, nausea, vomiting, and hematemesis. Upper gastrointestinal bleeding in patients treated with corticosteroids without a past history of upper gastrointestinal bleeding has been reported rarely. But the etiologic significance of the stress of status asthmaticus, administration of theophylline or corticosteroids...
A Case of Severe Pulmonary Complication and ARDS Secondary to Peanut Aspiration in 15 Month Old Male
Sung Keun Moon, Chang Keun Kim, Churl Young Chung
Clin Exp Pediatr. 1997;40(3):423-428.   Published online March 15, 1997
Foreign body aspiration(especially peanut) is the leading cause of accidental death in children under 1 year of age and most cases of serious aspiration occur between the age of 1 and 3. We report a case of severe pulmonary complication and adult respiratory distress syndrome(ARDS) secondary to peanut aspiration in 15 month old male in spite of all removal(9 pieces) by ventilating bronchoscope. Chest...
Original Article
A Study for the Normal Serum Carnitine Levelsand the Effect of Anticonvulsants on Serum Carnitine Levels in Pediatric Age
Byeong Eui Kim, Heung Dong Kim, Churl Young Chung
Clin Exp Pediatr. 1996;39(10):1414-1421.   Published online October 15, 1996
Purpose : This study aimed to evaluate the effect of anticonvulsants on serum carnitine levels as well as normal serum carnitine levels. Methods : We measured the serum carnitine levels in 53 healthy children(34 males, 19 females) and 115 epileptic children(55 males, 60 females) receiving a various antiepileptic drugs. We assessed the effects of antiepileptic drugs on serum carnitine level together with a correlation between...
Case Report
Four Cases of Iron Deficiency Anemia with Helicobacter pylori Infection
Houng Soung, Cheol Ho Chang, Churl Young Chung
Clin Exp Pediatr. 1996;39(8):1173-1178.   Published online August 15, 1996
Helicobacter pylori has become apparent that this organism is an etiologic agent of gastrits and peptic ulcer disease in humans. We present four cases of iron deficiency anemia, not specific causes, in 3 males and 1 female patients with Helicobacter pylori infection, who were treated with antibiotics and iron supplemented therapy. Diagnosis was confirmed by endoscopic biopsies and hematologic findings. A brief review of related...
A Case of Q Fever with Agranulocytosis
Seong Woo Choi, Ja Wook Koo, Heung Dong Kim, Churl Young Chung, Won Young Lee
Clin Exp Pediatr. 1995;38(6):848-852.   Published online June 15, 1995
A 9-year old boy suffered from fever 20 days. He lived in rural area near farms rearing cows, goats, sheep. He had fever for 20 days with mild respiratory symptom, hepatosplenomegaly and agranulocytosis. Coxiella burnetii infection was confirmed by the blood culture and demonstration of the specific antibodies in the indirect fluorescent antibody test. Four weeks later, agranulocytosis was improved...
Original Article
Epidemiology and Vaccine Efficacy of Measles During the 1993 measles Epidemic
Soon Ki Kim, Jong Woon Choi, Byong Kwan Son, Seung Nam Park, Churl Young Chung, Young Min Ahn, Chong Young Park, Ki Yang Ryoo, Woo Kap Chung, Hoan Jong Lee
Clin Exp Pediatr. 1995;38(6):778-785.   Published online June 15, 1995
Purpose : Because of increased measles incidence in Korea during 1993 and the recent finding of genomic differences between vaccine virus and contemporary wild measles viruses, we conducted a measles vaccine efficacy study involving children ages 1 to 5 yeark, with the demographic analysis of patients brought to the hospitals during measles outbreak that had occurred 1993 in Seoul and...
Case Report
Four Cases of Benign Neonatal Convulsion
Hwi Tae Kang, Heung Dong Kim, Young Ii Park, Churl Young Chung
Clin Exp Pediatr. 1995;38(5):692-696.   Published online May 15, 1995
Benign neonatal convulsions are classified into benign idiopathic neonatal convulsions(fifth day fits) and benign familial neonatal convulsions. Benign familial neonatal convulsions occur mostly on the second and third days of life with f amily history of autosomal 4ominant trait. The prognosis is favourable but idiopathic epilepsy m ay occur in 5 percent of patients. Benign idiopathic neonatal convulsions ocurr around the fifth...
Original Article
Comparison of Oxygenation and Lung Damage of High Frequency Flow Interruption to Conventional Ventilation in Surfactant Deficient Rabbits
Chang Keun Kim, Churl Young Chung, Hye Jae Cho
Clin Exp Pediatr. 1995;38(5):591-601.   Published online May 15, 1995
Purpose : This study was performed kto evaluate the High frequency flow interruption(HFF I) can prevent the lung injury and achieve a bettre oxygenation than conventional ventilation(C V) in surfactant deficient lungs when associated with lung volume recruitment and maintenance, and the need of background intermittent mandatory ventilation(IMV) to prevent the progressive atelectasis during HFFI. Methods : Surfactant deficiency was produced...
Yersinia pseudotuberculosis Infection Confirmed by Stool Culture in Children
Seung Nam Park, Kyeong Mi Jung, Ja Wook Koo, Churl Young Chung, Chong Rae Cho
Clin Exp Pediatr. 1995;38(2):189-194.   Published online February 15, 1995
Purpose : The clinical significance of Y. pseudotuberculosis infection has recently recognizd in various part of the world, because it can cause a wide range of clinical problems such as mesenteric lymphadenitis, septicemia, reactive arthritis, terminal ileitis, erythema nodosum, and a cute renal failure. We have experienced 19 children with Y. pseudotuberculosis infection confirmed by stool culture. Our aim in...
Recurrent Abdominal Pain in Children: Endoscopic Findings and Helicobacter pylori Infection
Cheol Ho Chang, Churl Young Chung
Clin Exp Pediatr. 1995;38(1):47-53.   Published online January 15, 1995
Purpose : Recurrent abdominal pain (RAP) in children is similar to nonulcer dyspepsia of adult. Recently, microscopic inflammation and Helicobacter pylori (H. pylori) infection have been suggested as possible causes of nonulcer dyspepsia in adults. The aim was to know the clinical significance of encoscopic findings and H. pylori infection in children with RAP. Methods : 128 children with RAP underwent...
Case Report
A Case of Bronchial Stenosis due to Endotrcheal Suction
Se Ki Oh, Young-Ill Park, Churl Young Chung, Hye Jae Cho
Clin Exp Pediatr. 1994;37(4):578-582.   Published online April 15, 1994
We experienced a acquired bronchial stenosis in a male premature infant who had recurrent postextubation atelectasis of the right lung. Bronchography showed the stenosis of the distal portion of right main bronchus and the proximal portion of intermediate bronchus and autopsy findings showed ill-defined irregulary elevated nodule with fibrotic scarring in the trifurcation of right main bronchus. Endotracheal suction was suspected...
A case of Aberrant Right Subclavian Artery Associated with Innominate Artery Compression Syndrome
Kyung Ho Ko, Young-Ill Park, Churl Young Chung
Clin Exp Pediatr. 1993;36(11):1626-1629.   Published online November 15, 1993
An aberrant right subclavian artery, the most common congenital anomaly of the aortc arch, is rarely symptomatic during the infancy, if an anomalous origin of a right common carotid artery is also associateda varient of innomiate artery comperssion syndrome. We experienced a case of an aberrant right subclavian artery associated with an anomalous origin of the right common carotid artery in...
A Case of Cryptococcal Lymphadenitis
Ho Sung Cho, Young Baek Hahm, Il Sin Moon, Churl Young Chung, Jung Weon Shim, Il Huang Ko
Clin Exp Pediatr. 1992;35(1):108-112.   Published online January 15, 1992
Cryptococcosis is a subacute or chronic mycotic infection caused by Cryptococcus neoformans with a special predilection for the lung, skin, central nervous system and lymphatic system. The authors have experienced a patient with cryptococcosis involving lymphatic system only. He was cured with combination therapy of Amphotericin-B and 5-Fluorocytosine for 6 weeks. Referential literatures were reviewed.
Original Article
A Clinical Observation of Intussusception in Infants and Children: Comparing the results of barium enema with that of controlled air insufflation.
Nam Heon Kim, Won A Park, In Ho Kim, Churl Young Chung, Sang Woo Kim
Clin Exp Pediatr. 1982;25(7):708-716.   Published online July 31, 1982
Intussusception which is the mot frequent cause of intestinal obstrucsion in childhood, is the invagination of a segment of the gastrointestinal tract into an adjacent segment. Since 1927, barium enema under fluoscopic guidance has been used widely as a therapeutic method. In 1953, Fiorito and Cuestas reported the use of controlled insufflation of air for diagnosis and treatment of intussusception....
Case Report
Two Cases of Postvaricella Reye Syndrome.
Won A Park, Sang Keun Chi, In Ho Kim, Churl Young Chung
Clin Exp Pediatr. 1982;25(5):528-532.   Published online May 31, 1982
Authors observed two cases of Reye syndrome in 7 and 8 year old male patients who had begun to vomit after chickenpox. The interval between the onset of varicella rash and encephalopathy of Reye syndrome was 4 days in both these cases. The initial laboratory findings revealed increased serum transaminase and blood ammonia levels which returned to normal on 18...
A Case of Report of Letterer-Siwe Disease.
Nam Heon Kim, Jung Ho Lee, In Ho Kim, Churl Young Chung, Jong Eun Joo, Ill Hyang Ko
Clin Exp Pediatr. 1981;24(12):1213-1217.   Published online December 15, 1981
We experienced a cass of Letterer-Siwe disease in 2 month old infant. The patient was presented charateristic clinical findings such as hepatosplenomegaly, petechia, anemia, gene-ralized lymphadenopathy, and lung infiltration. The diagnosis was confirmed by lymphnode biopsy and bone marrow aspiration, which was compatible to Letterer-Siwe disease. A poor prognostic factor in Histiocytosis X is younger age (below 18 month), hepatospleno-megaly, anemia,...
Original Article
Epidemiologic Study of Enterobacteriaceae Infection of Nursery Room.
Byung Zoo Choi, Hae Sook Kim, In Ho Kim, Myung Sook Lee, Churl Young Chung
Clin Exp Pediatr. 1981;24(6):525-534.   Published online June 15, 1981
We found enterobacteriaceae in throat culture of premature infants in our nursery who showed poor appetite, poor activity and irregular weight gain and was diagnosed as having respiratory distress syndrome and pneumonia from May 1980 to August 1980. At this time we also found enterobacteriaceae in throat cultures of three normal newborns whose each age was at 1 hr old,...
Case Report
A Case of Chronic Myelocytic Leukemia associated with Neurofibromatosis.
Byung Zoo Choi, Jung Ho Lee, In Ho Kim, Seoc Koo Bae, Churl Young Chung, Byung Soo Kim
Clin Exp Pediatr. 1980;23(10):849-854.   Published online October 15, 1980
There have been few cases of Neurofibromatosis associated with Chronic Myelocytic Leukemia in literature and we found only one report in Korea which described the association of Chronic Myelocytic Leukemia with Neurofibromatosis. We report a case of patient whose clinical and hematological findings were compatible with Chronic Myelocytic Leukemia and Neurofibromatosis. Busulfan was used in the treatment of this patient...
A Case of 18-Trisomy Syndrome.
Hae Soo Kim, In Ho Kim, Myung Sook Lee, Churl Young Chung
Clin Exp Pediatr. 1980;23(9):757-760.   Published online September 15, 1980
A case of 18-Trisomy Syndrome in a female newborn infant who was born to a mother of 32 years with hydramniosis old at PAIK hospital was presented. His father who was normal and 36 years old age. This baby had grossly multiple anomalies those were charactcrized by prominant occiput, small eyes and palpebral fissure, low set and malformed esars, hypoplasia...
A Case of Omphalocele.
Kil Woo Kim, Sang Chil Yoon, Myoung Sook Lee, Churl Young Chung
Clin Exp Pediatr. 1978;21(11):813-816.   Published online November 30, 1978
Omphalocele is a rare congenital malformation which is a herniation of the abdominal viscera into the base of the umbilical cord. We experienced a ruptured large omphalocele of short duration which contained of intestines, stomach, liver and speen without major of additional anomalies. He was repaired with the simple skin converage as a part of second staged operation. He had...
Reye's Syndrome 5 Cases of Report and Review of Literatures.
In Ho Kim, Kil Woo Kim, Myoung Sook Lee, Churl Young Chung
Clin Exp Pediatr. 1978;21(11):806-812.   Published online November 30, 1978
Authors had experienced 5 cases of Reye's syndrome in a 15mo. old female patient, 16mo. old male patient, two cases of 4 years old male patients, and 9mo. old male infant who were compatible with this syndrome since Mar. 1976. 2 cases of this patients have been recovered and observed at O.P.D. of ped. Department. Laboratory findings disclosed increased SGOT,...
A Case of Athyrotic Cretinism.
Sang Chil Yoon, Kil Woo Kim, Myoung Suk Lee, Churl Young Chung, Jong Eun Joo, Ill IIyang Ko
Clin Exp Pediatr. 1978;21(9):594-599.   Published online September 30, 1978
This paper presented a case of athyrotic cretinism in a 4 months old female infant. Durring neonatal 7 period she suffered from prolonged jaundice for about 50 days On admission, elinical manifestations suggesting of hypothyroidism were umbilical hernia, feeding problems due to large tongue, respiratory difficulty, lethargy and skin changes Roengenogram of the long bone series revealed the absence of...
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