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Original Article
Injury of neurons by oxygen-glucose deprivation in organotypic hippocampal slice culture
David Chanwook Chung, Kyung Sik Hong, Jihui Kang, Young Pyo Chang
Clin Exp Pediatr. 2008;51(10):1112-1117.   Published online October 15, 2008
Purpose : We intended to observe cell death and apoptotic changes in neurons in organotypic hippocampal slice cultures following oxygen-glucose deprivation (OGD), using propidium iodide (PI) uptake, Fluoro-Jade (FJ) staining, TUNEL staining and immunofluorescent staining for caspase-3. Methods : The hippocampus of 7-day-old rats was cut into 350 µm slices. The slices were cultured for 10 d (date in vitro, DIV...
Case Report
Primary leiomyosarcoma of the chest wall in a child : a case report
Jae Hyuk Choi, David Chanwook Chung, Mee Jeong Lee
Clin Exp Pediatr. 2008;51(1):98-101.   Published online January 15, 2008
Leiomyosarcoma is an uncommon soft tissue sarcoma of mesenchymal cell origin, which shows smooth muscle differentiation. Leiomyosarcoma is seldom found in the pediatric population, and accounts for fewer than 2% of all soft tissue sarcomas. Leiomyosarcoma of the chest wall is extremely rare in children. We report here a case of an 8-year-old boy with a primary leiomyosarcoma that was...
Original Article
High-resolution computed tomography findings of lung parenchyme changes in very low birth weight infants treated with oxygen
Young Man Jin, David Chanwook Chung, Young Pyo Chang, Yung Suk Lee, En Sun Lee
Clin Exp Pediatr. 2007;50(3):255-261.   Published online March 15, 2007
Purpose : The objective of this study is to observe high-resolution computed tomography (HRCT) findings of lung parenchyme in very low birth weight (VLBW) infants between the corrected age of 38-42 weeks who were treated with oxygen after birth, and to compare them to the clinical severity of bronchopulmonary dysplasia (BPD). Methods : The lungs of fourty-four VLBW infants with gestational...