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Original Article

Urine Organic Acid Analysis of Patients with Febrile Seizures

Dong Soo Shin, Gun Jun Lee, Kyeung Ja Lee, Won Il Park, Eun Joo Bae, Hong Gin Lee

Clin Exp Pediatr. 2004;47(11):1205-1209. Published online November 15, 2004

Purpose : Febrile seizure, the most common seizure disorder in children between 6 months and 5 years of age, is mostly caused by viral infections, except severe CNS infection. It can also be caused by disorders in organic acid metabolism, especially accompanied by fever. Therefore we decided to investigate the relationship between children with febrile seizures and disorders in organic...

Quantification of Organic Acids in Amniotic Fluid for Prenatal Diagnosis of Organic Acidemia

Chang Bum Koh, Dong Soo Shin, Eun Joo Bae, Won Il Park, Kyeung Ja Lee, Hong Jin Lee, Young Jo, Seung Won Lee, Ui Sun Noh

Clin Exp Pediatr. 2004;47(10):1047-1052. Published online October 15, 2004

Purpose : Since 1997, the quantification of organic acids in urine has become possible in Korea. This helped to diagnose a great variety of inborn errors of metabolism. However, we still don't know the normal value of organic acids in amniotic fluid, therefore it is impossible for doctors to make a correct diagnosis of inborn errors of metabolism in prenatal...

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