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Case Report

H J Suh, E H Kang, K C Han, S K Moon

Clin Exp Pediatr. 1982;25(9):954-958. Published online September 30, 1982

A case of Letterer-Siwe disease in a 2 year old boy manifesting such classic signs described by Siwe as, hepatosplenome^aly, swelling of lymph node, bleeding tendency, anemia, fever and bony skull defects is presented. The diagnosis was confirmed by clinical symptoms, laboratory data, histopathologic and radiologic fingings. The authors report a fatal case which was treated in this hospital with review of pertinent literatures.

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