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Case Report
Two Cases of Castlema's Disease in Childern
Eun Ah Kim, Chong Guk Lee, Han Sung Kim
Clin Exp Pediatr. 2003;46(2):203-206.   Published online February 15, 2003
Castleman's disease is an atypical lymphoproliferative disorder of unknown origin. It has three histologic variants(hyaline vascular, plasma-cell, and mixed) and two clinical types(localized and multicentric). Some sufferers have constitutionalg symptoms and laboratory abnormalities such as anemia, hypoalbuminemia, hypergammaglobulinemia, and elevated erythrocyte sedimentation rate. The localized form is cured by complete surgical excision whereas the multicentric form is managed by prednisone...


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