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Original Article

Two Cases of Cerebral Gigantism (Sotos Syndrome).

Hee Jeung Ahn, Young Tae Kim, In Hoon Seol, Jeh Hoon Shin

Clin Exp Pediatr. 1990;33(8):1155-1158. Published online August 31, 1990

Cerebral gigantism, the condition described by Sotos et al in 1964, consists of excessively rapid growth rating from infancy followed by a normal growth rate, acromegalic features, and a non- progressive neurological disorder manifested by clumsiness. The etiology of cerebral gigantism is not clear. Increased growth hormone levels have not been documented and somatomedin activity was found to be within normal range as yet...

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