Hemolytic uremic syndrome is the most common cause of acute renal failure in childhood. Atypical hemolytic uremic syndrome which is not usually associated with prodromal symptoms has a higher mortality rate and more tendency to progress to chronic renal failure. Children younger than two years of age are a more susceptible to pneumococcal infection and can develop more serious disease.... |
Purpose : Most of childhood MCNS has a long disease course with frequent relapses. This study was designed to analyze the long-term clinical course of childhood MCNS, focusing at relapsing pattern, treatment response and complications. Mothods : The medical records of 137 children with biopsy-proven MCNS observed during 1976 ti 1996 were analyzed retrospectively. They were classified as initial responders(111 patients,... |
Diffuse mesangial sclerosis(DMS) is one of the underlying pathology of congenital and infantile nephrotic syndrome. Infants with DMS develop nephrotic syndrome before 2 years of age and progress to end stage renal disease within 3 years of age. The authors experienced a case of isolated DMS in a 4-month-old male infant who had nephrotic syndrome for 1 month. The diagnosis... |
Purpose : The urinary mass screening program for the detection of proteinuria had been performed for a school age population in the city of Seoul since 1981. However, systematic evaluation for this program had never been done. We, therefore, designed a systematic evaluation in corporation with the Seoul School Health Center for students with proteinuria identified in the mass screening to determine the prevalence... |
A case of lead nephropathy is presented and recent literatures are reviewed. A 11 year old boy had been admitted to National Medical Center, with a chief complaint of gross hematuria during follow up of lead poisoning. He had a history of ingestion of herb pills medication for 6 months with his twin sibling who had been diagnosed as lead... |
Unilateral lung agenesis is defined with absence of parenchyme, supporting structures and airway below the level of the carina. Lung agenesis is associated with other anomaly of cardiovascular system, musculoskeletal system and genitourinary system in about 50% cases. In most cases, the diseases is found due to respiratoru problems. Prognosis is variable but largely depends on the associated anomaly and... |
We analyzed medical records of 35 patients with Hepatitis B virus-associated Membranous Nephropathy proven by kidney biopsy at SNUCH from Jan. 1975 to Jun. 1990. Clinical presentation, laboratory and pathologic findings were compared between remission group (who are free of proteinuria and edema in current status) and nonremission group (who have either proteinuria or edema). Age at onset was younger in remission group (4.51 ±2.93... |
Meconium peritonitis is an aseptic peritonitis caused by spill of meconium in the abdominal cavity through discontinuation of the intestine by any cause, which have taken place during intrauterine or perinatal life. We experienced a case of meconium peritonitis in an 1-day-old male neonate who had the chief complaint of dyspnea and abdominal distension. The review of the literature was made briefly. |
In this study we compared between the patients with recurrent gross hematuria (group 1, n=45) and * with nephrotic range proteinuria (group 2, n=21) in IgA nephropathy who were admitted to Seoul National University Children’s Hospital during the period from January, 1980 to December, 1989. The results of the study were as follows. 1) Age of onset and sex ratio were not different between the... |
A female child aged 7 months was admitted because of high fever, vomiting and stuporous conciousness and revealed to have hemolytic uremic syndrome. Anuria persisted 13 days and required peritoneal dialysis 4 times a day during the anuric period. Her kidney function recovered somewhat after dialysis but neurologic complications of marked hydrocephalus and brain atrophy remained. |
Uriary mass screening program for the detection of proteinuria had been performed for a school- age population in the city of Seoul since 1981. Annually, about half million students, who comprised 3 different age group, corresponding to the averages of 11,14, and 17 years, had been examined. A systematic clinical evaluation was designed for students with proteinuria identified in the mass screening through ’87... |
To assess the clinical significance of histopathologic variants of minimal change nephrotic syn- drome (MCNS) by light microscopic findings, 148 biopsy proven MCNS patients, who were admitted to Seoul National University Hospital between the period from January 1976 to December 1986, were analyzed according to clinical findings, steroid responsiveness, and follow up status in relation to the pathologic variants. The followings are summary and conclusion. 1) Significantly... |
Department of Pathology, College of Medicine, Seoul National University Basement membrane nephropathy is regarded as a separate disease entity recently by many authors. We have experienced a case of Thin Basement Membrane Nephropathy in a 4 years old female patient. The Glomerular Basement Membrane is thinned out measuring 1,000 A to 1,400 A. thickness having smooth inner and outer contour. In addition to the... |
A case is presented of a 15-year old girl with clinical and laboratory findings Strongly suggestive of poststreptococcal glomerulonephritis but without abnormalities in the urine. Repeated examinations of the urine demonstrated absence of proteinuuria and hematuria throughout a nineteen-day hospital course. Her renal biopsy specimen revealed small scattered intramembranous, subendothelial and mesangial deposits in. immunofluorescence and electron microscopy, but essentially normal pattern in light microscopy indicating... |
Two cases of IgA nephropathy in an 11-year-old girl(Case I) and a 10-year-old boy(Case II) were presented. Case I, an 11-year-old schoolgirl, had recurrent painless hematuria of 6-month duration which began with URI symptoms at the onset. No edema was noted and urine volume was sufficient throughout the course. Mild proteinuria had been noted from time to time. Blood pressure... |