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Case Report
Acute Alcohol Intoxication in a Child
Mee Jeong Lee, Hyunmi Kim, Sang Gyu Park, Soo Youn Ham
Clin Exp Pediatr. 2000;43(4):588-591.   Published online April 15, 2000
Information on ethyl alcohol intoxication in children is scarce. It is generally believed that children are more vulnerable to ethyl alcohol intoxication than adults. However, little information has been published on the effects of ethanol in the pediatric age group. The incidence of hypoglycemia and convulsions following ethanol intoxication is not known. We report a fatal case of acute alcohol...
Original Article
Effects of Thioredoxin on Apoptosis-Inducing Neuronal Cell Injury
Hyunmi Kim, Gyoung Hee Kim, Yoon Song Lee
Clin Exp Pediatr. 1999;42(6):825-832.   Published online June 15, 1999
Purpose : Thioredoxin is an endogenous antioxidant. It regulates the activities of transcriptional factors such as NF-kB(nuclear factor kappa B)and AP-1(activator protein-1) and it increases the synthesis of cytokines, preventing cellular proliferation and apoptosis. The aim of this study was to clarify the role of thioredoxin on apoptosis-inducing neuronal cell injury. We investigated the protective effects of thioredoxin against apoptosis-inducing...
Effects of Thioredoxin on Oxidative Neuronal Cell Injury
Hyunmi Kim, Gyoung Hee Kim, Yoon Song Lee
Clin Exp Pediatr. 1999;42(5):686-696.   Published online May 15, 1999
Purpose : Thioredoxin is an endogenous antioxidant which directly scavenges reactive oxygen species(ROS) and regenerates oxidatively damaged protein by reducing potential at the redox active disulfide(-Cys-Gly-Pro-Cys-) site. Under oxidative stress, thiredoxin plays a protective and adaptative role by inducing expressions. The aim of this study was to clarify the role of thioredoxin on oxidative neuronal cell injury. We investigated the...
Case Report
A Case of Pure Red Cell Anemia Complicated by Antiepileptic Drugs
Hyunmi Kim, Sang Gyu Park, Sung Ryeul Kim
Clin Exp Pediatr. 1999;42(2):264-267.   Published online February 15, 1999
A 12-year-old boy developed pure red cell anemia(PRCA) during a combination therapy of antiepileptic drugs(AEDs) for epilepsy. His complex partial seizure was intractable to monotherapy. During 7 months of treatment, he was treated with Vigabatrin, Carbamazepine and Valproate. While switching from Carbamazepine to Valproate, he presented anemia but with no jaundice. His hemoglobin was 4.1g/dl bone-marrow biopsy revealed erythroid hypoplasia...
Original Article
Seizure Types and EEG Findings of Juvenile Onset Idiopathic Generalized Epilepsy
Hyunmi Kim, Won Seop Kim, Jong Shin Kim, Kangho Cho, Ki Joong Kim, Yong Seung Hwang
Clin Exp Pediatr. 1997;40(7):991-998.   Published online July 15, 1997
Purpose : Juvenile myoclonic epilepsy, juvenile absence epilepsy, and epilepsy wth generalized tonic clonic seizure(GTCS) on awakening are the three syndromes of idiopathic generalized epilepsy of adolescent onset currently included in the classification of epilepsy syndromes of the International League Against Epilepsy(ILAE). Although they differ in their predominant seizure types, the syndromes share several seizure types. Also, there are no unique electrophysiologic or genetic markers....
The Usefulness of Clinical Scoring System as Prognostic Predictor in Neonatal Seizure
Hyunmi Kim, Gyoung Hee Kim
Clin Exp Pediatr. 1996;39(6):829-838.   Published online June 15, 1996
Purpose : Neonatal seizure is usually the presentation of underlying neurologic dysfunction rather than a disease and have high mortality and morbidity as sequalae. Therefore, the parameter predicting the neurologic prognosis is necessary. This study was performed to identify the usefulness of clinical scoring as predictor in neonatal seizure by analyzing outcomes. Methods : From 1982 to 1994, 101 neonates were admitted to Neonatal Intensive...
Predictor of Fatty Liver in Obese Children
Hyunmi Kim, Young Mi Hong, Gyoung-Hee Kim, Jung Hyun Yu
Clin Exp Pediatr. 1996;39(6):803-810.   Published online June 15, 1996
Purpose : The childhood obesity is currently increasing. The childhood obesity is difficult to treat and the response of treatment is transitory because it is caused by the hyperplasia of fatcells. The complications of obesity are hyperlipidemia, hypertension, diabetes, artherosclerotic coronary arterial disease and fatty liver. Therefore the early diagnosis and prevention of obesity from childhood is very important. This study...