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Neuronal migrational disorders of the brain represent abnormalities in the formation of
the neocortex caused by faulty migration of the subependymal neuroblasts. The
neuroblasts normally migrate between the sixth and 15th gestational week and in doing
so form the six-layered neocortex. When the migration does not occur in a normal
fashion the resultant brain anomalies include lissencephaly, pachygyria, schizencephaly,
hemimegalencephaly, heterotopia, and polymicrogyria.
Neuronal heterotopia is... |
