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Original Article

Studies on the diuretic activity of the serum of the patient with diabetes insipidus

Kook-Choo Rie, Yong-Soo Yun, Ho-Sung Lee, Jeong-Ki Seo, Dong-Hwan Lee

Clin Exp Pediatr. 1976;19(2):99-112. Published online February 28, 1976

Diabetes insipidus is the syndrome which results from abnomality in production or release of ADH. Recently there have been used two nonhormonal forms of therapy in the treatment of DI: 1)Various diuretics, primarily thiazides and 2)The oral hypoglycemic agents, the sulfonlureas. Arduino and other numerous invesgators demnstrated that sulfonylurea chlorpropamide (Diabinase) and tolbutamide(Drinase) had a ADH-Iike effect in a patient...

Experimental Studies on the Influences of circulatory Disturbancesc of the Central Nervous System in Producing Diuretic Substance

Kook-Choo Rie

Clin Exp Pediatr. 1975;18(3):177-188. Published online March 31, 1975

In 1972, the Author observed that there showed a marked diuresis by the hypotonic osmotic stimulation with H2O into the anterior hypothalamus of rabbit, and at the same time a strong diuretic substance appeared in the serum of the same rabbit. Coworker Kim observed that diuretic substance appears in the convalescent serum of the nephrotic syndrome, coworker Chung observed diuretic...

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