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Original Article

Discordance between antibiotic therapy and recurrent urinary tract infections in young children with thirdgeneration cephalosporin-resistant infections

Yusin Kim, Hyun A Lee, Gil Lee, Kyungseok Park, Ye Kyung Kim, Peong Gang Park

Background: Third-generation cephalosporins remain the empirical mainstay for pediatric urinary tract infections (UTIs) in Korea, yet the resistance rate now approaches 30%, thereby threatening treatment effectiveness.
Purpose: To determine whether completing a cephalosporin regimen, despite in vitro resistance, increases early UTI recurrence rates. Methods: We retrospectively reviewed the cases of children aged <24 months with their first Gram-negative UTI admitted in 2020–2024. Three exposure groups were defined: susceptible isolates treated...

DOI: https://doi.org/10.3345/cep.2025.01417 [Accepted]

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