Purpose : The purpose of this study was to determine the incidence and potential predictors of weight gain in older children and teens treated with valproate (VPA) for epilepsy. Methods : Sixty-five subjects aged 8 to 17 years of age, who began VPA treatment between January 1, 2001, and December 31, 2004, and who had documented weight and height measurements... |
Purpose : This study aimed to investigate whether exogenous thyroxine(T4) treatment to alcohol-fed dams would ameliorate the detrimental effects of alcohol on the postnatal development of neuropeptide-Y(NPY)-containing neurons of the cerebral cortex and hippocampus of the offspring. Methods : Time-pregnant rats were divided into three groups. An alcohol-fed group A received 35 calories of liquid alcohol diet daily from gestation day... |
Purpose : We compared the pain reducing effect of orally administered glucose solution with EMLA cream and pacifiers during venipuncture in newborn infants. Methods : Fifty newborn infants(30 prematures) were enrolled in this study. We performed these four pain-reducing methods to all infants in serial order. Group A(control) did not receive any treatment; to group B, EMLA cream was applied on... |
Purpose : The aim of the this study was to evaluate the effect of various perinatal conditions on TSH and thyroid hormone levels in cord blood. Methods : Cord blood samples were collected from 130 neonates immediately after birth. TSH, T3, and free T4 levels were measured by the radioimmunoassay(RIA) method. The effects of gestational age, sex, birth weight, delivery method,... |
Purpose : The purpose of the present study was to access the prevalence of orthostatic dysregulation(OD) and the frequency of each category for major and minor criteria among elementary school students using the OD questionnaire. Methods : We carried out inquiry by questionnaire as to the frequency of OD among two elementary schools with 725 students, 10 to 12 years of... |
Objective : The purpose of this study was to assess the patterns of medical care utilization and factors which determine medical care utilization of elementary school children after the implementation of medical reform. Methods : We performed the questionnaires on 1,031 children from two elementary schools in Gwangju city from June 1 to 30 June, 2001. These data were compared with... |
Purpose : The aim of this study was to evaluate the behavioral and affective characteristics of children who thought they were short. Methods : Fifteen hundred and twenty-two students of four elementary and middle schools in Gwangju City completed a battery of questionnaires asking about stature-related stress, self-esteem, and personality characteristics. The children were divided into three groups and compared according... |
Maternal varicella resulting in viremia may transmit the virus to the fetus by either transplacental spread, or by ascending infection from lesion in the birth canal. The characteristic symptoms consist of skin lesions in dermatomal distribution, eye diseases, neurological defects, and limb hypoplasia. Varicella of the newborn is a life-threatening illness that may occur when a newborn is delivered either... |
Craniofrontonasal dysplasia(CFND), a rare congenital syndrome, is characterized by varying degrees of frontonasal dysplasia, craniosynostosis, and variable extracranial abnormalities. It was first reported by Cohen in 1979. The inheritance pattern is not straightforward. Although all modes of Mendelian inheritance have been suggested, the most plausible explanation is that this is an X-linked condition with the unusual situation of complete expression... |
Purpose : To review the seizure-related complaints and analyze the relationship between admission rates and clinical features in children who had visited the emergency department with seizures. Methods : Retrospectively, we reviewed 180 patients(male 100, female 80) suffering from seizures, who had visited to the emergency department of Chosun University Hospital from January 2000 to June 2002. We have analyzed the... |
Congenital chloride diarrhea is a serious autosomal recessive disease, and defect of intestinal electrolyte absorption that involves, specifically, Cl-/HCO3- exchange in the distal part of the ileum and colon. The clinical feature is dominated by profuse, watery diarrhea containing high concentrations of chloride(>90 mmol/L) and sodium. The chloride loss results in severe dehydration with a hypochloremic alkalosis. The molecular pathology... |
Purpose : Long-term stress to the fetus causes alterations in adrenal steroidogenesis. The purpose of this study was to analyze the association of cord blood cortisol with stress during delivery. Methods : Cord blood samples were collected from 58 neonates at once to labor. Cortisol was measured by RIA method(DPC, USA). Cortisol level according to gestational age(<34, 34-37, >38 wks)... |
Purpose : The aim of this study is to find out the distribution of illness, patterns of medical care utilization and factors determining medical care utilization in elementary school children. Methods : We performed the questionnaires in Gwangju city on 2,036 children of two elementary schools from June 1 to June 30, 1998. Results : The prevalence rate of illness was 32.3%.... |
Purpose : This study was undertaken to review the clinical and hematologic findings of the preterm infants delivered from pregnancy induced hypertension(PIH) mothers. Methods : The data were collected by reviewing the medical records on the current prognosis of preterm birth and sending questionnaires on the status of NICU. We reviewed the medical records from two university hospitals and two resident training hospitals in... |
Purpose : This study was designed to evaluate the relationship between obesity and depressive trends in elementary school children. Methods : In 1999, we surveyed 2,091 elementary school children(1,079 boys and 1,012 girls) whose ages ranged from 10 to 12 years. Obesity was defined as an obesity index over 20 percent. The degree of depression was compared between the obese group... |
Purpose : To examine the prevalence of obesity in elementary school-aged children in Gwangju, and long term courses of those obese children. Methods : We examined children aged 7 to 12 in the total number of 3,028 elementary school students consisting of 1,579 boys and 1,449 girls between 1994 and 1999. Obesity was defined as weight that exceeded the standard weight... |
Purpose : Leptin, the product of the ob gene is primarily by adipose tissue but also by the human placenta. Leptin may also have a role as a regulator of fetal growth and development during normal pregnancy as well as in pregnancies associated with anomalous fetal growth. Our study aimed to discover whether or not leptin concentration in neonatal cord... |
Purpose : The purpose of the study was to determine the prevalence of chronic recurrent headache and the factors associated with it among primary school children. Methods : The survey was performed by a special questionnaire on one thousand and eleven children in grades 4 to 6 at primary schools from 1 to 30 June 1999 in Gwangju city. Results : Prevalence... |
Congenital epulis of the newborn refers to a very rare gingival tumor that occurs along the anterior alveolar ridge in newborn infants. We report a neonate with 3¡¿2¡¿1.5cm mass protruding from the mouth. This was a pinky, red solid pedunculated mass, attached to the maxillar left canine region of the alveolus at birth. The tumor's large size partially obliterated the... |
Catel Manzke syndrome is characterized by hyperphalangy of the index fingers associated with Robin malformation sequence. The etiology of Catel Manzke syndrome is still uncertain, with the majority of cases being sporadic. Careful observation to recognize upper airway obstruction secondary to the Robin sequence should be made a part of routine care for newborns with this disorder. Failure to thrive... |
Purpose : Theophylline, an adenosine antagonist commonly used in premature infants to treat apnea, has been shown to decrease erythropoietin levels in adults. We studied the effect of theophylline on serum erythropoietin levels in premature infants with apnea. Methods : Subject were 12 premature infants with apnea who were admitted to the NICU, Chosun University Hospital. The first dose of theophylline was 5mg/kg, given... |
Herpes zoster, an inflammatory human disease caused by varicella zoster virus, is characterized by papulovesicular lesions along the distribution of a sensory nerve. We experienced a herpes zoster in 23 day old premature infant. The papules were distributed on his skin corresponding to the dermatomes innervated by the left Th3-Th4. The diagnosis of herpes zoster was made with dermatomal distribution of typical skin lesions, pathologic... |
Chondrodysplasia punctata is a rare congenital disorder of bone, which is characterized by radiographic manifestation of punctate calcification in epiphyseal areas, preformed in cartilage. We experienced a case of the non-rhizomelic chondrodysplasia punctata in a male neonate who showed cataract, saddle nose, stippled calcification on X-ray without coronal cleft of verte-brae and rhizomelia. |
Drug-induced toxic epidermal necrolysis (TEN) is a bullous erythematous disease that is characterized by the appearance of scaled lesions and large sheets of pilling on the skin. A case of TEN occured in a 10 month old female patient. The characteristic skin lesions of TEN developed after oral administration of carbamazepine for a partial seizure. Thig case consists of prodrome of... |
The effects of Equiseti Herba water-heating extract on the kidey & liver of rats were studied in 25male Sprague-Dawley rats evenly divided into five groups, i.e., 5 rats each. The group I, which served as control and the group II, III, IV, were fed 300 mg/kg, 500mg/kg, 1000mg/kg of Eqiseti Herba water-heating extract daily for one week, respectively. The group... |
The antioxidant enzymes superoxide dismutase, catalase and glutathione peroxidase and the lipid peroxidation were assayed in erythroctyes from the cord blood of 25 fullterm newborn infants and their maternal blood abtained immediatedly after normal delivery. Superoxide dismutase and catalase activites in cor blood erythroctytes were significantly lower when compared with their mothers, but glutathione peroxidase activities were not significantly lower.... |
The Cornelia de Lange syndrome is characterized by severe growth and mental retardation, typical face, and low-pitched growling cry. We had experienced two cases of Cornelia de Lange syndrome in korean male infants. The baby showed microbrachycephaly, typical appearance of face with low forehead, bushy eyebrows, long curely eyelashs, thin lip with cleft palate, low set ears, generalized hirsutism and growth retardation... |
For exploitation of new antidiarrheal agents to heat-labile enterotoxin (LT) produced by enterotox- igenic E. coli, we have tested several drugs by rabbit ileal loop assay and obtained some significant results. L-glutathione (20 mg), P-chloromercuriphenyl sulfonic acid (20 mg) and water heating extract of Prunus mume (20 mg) reduced LT-mediated intestinal fluid secretion in rabbit ileal loop assay by 92%, 87%, 92% respectively. Maleate,... |
This study was performed to evaluate the changes of measles specific IgG antibody titer using enzyme linked immunosorbent assay (ELISA) on the sera of various groups of age. We obtained the following result: 1) Out of 118cases, 99cases (83.9%) were vaccinated children and 19cases (16.1%) were unvac- cinated children. Among them, the number of cases who had been infected with measles were 17 cases (17.2%) in... |