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Case Report
Topiramate can reduce the number of episodic attacks in cyclic vomiting syndrome : a case report
Mi-Sun Yum, Keun Wook Bae, Su Jeong You, Tae Sung Ko
Clin Exp Pediatr. 2007;50(4):386-389.   Published online April 15, 2007
Cyclic vomiting syndrome (CVS) is a paroxysmal, recurrent vomiting disorder of unknown pathophysiology and target organ. It has been hypothesized that CVS shares the same mechanism as migraine. We describe here a 5-year-old boy with CVS characterized by episodic vomiting attacks. These recurrent vomiting episodes began at 3 years of age, occurred every month and lasted for 5 days at...
Original Article
Clinical Study of Children Using Home Mechanical Ventilation
Young Joon Ahn, Seung Hyeon Lee, Hyo-Bin Kim, Seong Jong Park, Tae Sung Ko, Soo-Jong Hong
Clin Exp Pediatr. 2005;48(4):401-405.   Published online April 15, 2005
Purpose : The use of mechanically-assisted ventilators at home reduces morbidity and improves the quality of life in children with chronic respiratory failure. But in Korea there is no clinical data of children with home mechanical ventilation. We investigated ventilator types, duration, the causes of failure or death, and the cost needed for care. Methods : We retrospectively analyzed the medical...
Case Report
A Case of Micturition Syncope in a Child
Sun Youn Lee, Su Jeong Ryu, Deok Soo Kim, Young Hwue Kim, Tae Sung Ko, Jae Moon Kim
Clin Exp Pediatr. 2003;46(12):1274-1278.   Published online December 15, 2003
Syncope in children and adolescents have a common occurrence according for up to 15% before adulthood. Micturition syncope, a kind of situational syncope, can be considered a form of reflex syncope. It can typically occur in healthy young men after rising from bed in the early morning who experience sudden loss of consciousness during or immediately after urination. The mechanism...
A Case of Moyamoya Disease in a Child with Alagille Syndrome
Mi Rang Lim, So Yaun Lee, Deok Soo Kim, Kyung Mo Kim, Tae Sung Ko
Clin Exp Pediatr. 2003;46(1):86-90.   Published online January 15, 2003
Alagille syndrome is a autosomal dominant disorder characterized by intrahepatic bile duct paucity and resultant chronic cholestasis in combination with cardiac(mainly peripheral pulmonary stenosis), skeletal, ocular, and facial abnormalities. In addition to the pulmonary stenosis, in large series, anecdotal reports of vascular lesions have concerned the renal artery, aorta, hepatic artery, carotid artery, celiac artery or subclavian artery. Theses diffuse...
Original Article
Clinical Study of Renal Cystic Diseases in Children
Ja Hyung Kim, You Jeong Kim, Byeong Seon Lee, Tae Sung Ko, Young Seo Park
Clin Exp Pediatr. 2002;45(2):232-239.   Published online February 15, 2002
Purpose : Renal cystic diseases comprise a mixed group of heritable, developmental and acquired disorders. Recently the use of imaging modalities such as ultrasonography and radionuclide scanning has increased the detection rate of renal cystic diseases. We studied to review the clinical features and treatment of renal cystic diseases in children. Methods : This study was performed in 95 children with...
Clinical Lecture
Surgical Candidates for Intractable Pediatric Epilepsy
Tae Sung Ko
Clin Exp Pediatr. 2002;45(2):159-165.   Published online February 15, 2002
Original Article
MELAS Syndrome Confirmed by Mitochondrial DNA Analysis in Siblings
Young Ghil Rah, Soo Ahn Chae, In Suk Lim, Dong Keun Lee, Byoung Hun Yoo, Tae Sung Ko, Han Wook Yoo
Clin Exp Pediatr. 1999;42(3):412-418.   Published online March 15, 1999
MELAS(mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes) syndrome is a major subgroup of mitochondrial myopathy. Recent advances in molecular genetics revealed specific mutations in mitochondrial DNA which cause MELAS. We described here clinical and molecular genetic findings of sister and brother with MELAS syndrome. For molecular genetic studies, DNAs from peripheral blood nucleated cells were used. And the substitution...
Case Report
Four Cases of The Imported Falciparum Malariain Childre
So Young Lee, Tae Sung Ko, Hyun Sook Chi, Young Seo Park
Clin Exp Pediatr. 1997;40(2):249-253.   Published online February 15, 1997
Malaria is a protozoan disease transmitted by the bite of female Anopheles mosquitoes. Only four species of Plasmodium can infect human, which are P.vivax, P. ovale, P. malariae, and P. falciparum. We experienced four cases of the imported falciparum malaria in children who were admitted due to fever, vomiting, diarrhea, abdominal pain, lethargic state, and/or altered mentality after traveling Kenya and Tanzania without...
A Pediatric Case of MELAS Syndrome Associated with Insulin-dependent Diabetes Mellitus
Kyung Ran Park, Hye Won Park, Tae Sung Ko, Hae Il Cheong, Sei Won Yang, Young Seung Hwang, In Won Kim, Je Geun Chi
Clin Exp Pediatr. 1996;39(10):1461-1465.   Published online October 15, 1996
MELAS(mitochondrial myopathy, encephalopathy, lactic acidosis, and sroke like episodes) is a major subgroup of heterogeneous mitochondrial encephalopathy. Recent advances in molecular genetics revealed specific mutations in the mitochondrial DNA causing MELAS. We described clinical and molecular genetic findings of a 13-year-old boy with MELAS syndrome associated IDDM(insulin dependent diabetes mellitus). For molecular genetic studies, DNAs from peripheral blood nucleated cells were used. And the A→G...
Original Article
The Study of Distribution of HI Antibody Titers Aganist Japanese Encephalitis Virus Among Children in Seoul
Jin A Kim, Tae Sung Ko, Young Seo Park, Hyung Nam Moon, Chang Yee Hong, Hae Wol Cho
Clin Exp Pediatr. 1996;39(2):230-237.   Published online February 15, 1996
Purpose : Incidence of Japanese encephalitis has been markedly decreased, but this disease is known to be high and lethal in the young age group. This study was designed to find out the HI antibody titers and associated factors of Japanese encephalitis of children in Seoul, and to establish the plan of vaccination. Methods : The survey was conducted from the...
Auditory Brainstem Responses in Premature and Fullterm Infants
Hyun Mi Kim, Tae Sung Ko, Ki Soo Kim, Moo Song Lee, Kyung Hee Kim
Clin Exp Pediatr. 1995;38(8):1036-1045.   Published online August 15, 1995
Purpose : We tried to know normal range of auditory brainstem responses in premature and fullterm infants who have no rksk factor during perinatal period and to determine that the abnormal ABR in premature and fullterm infants may predict developmental delay. Methods : ABR evaluations were performed on 283 premature and fullterm infants from NICU of the Asan Medical Center during...
Infectious Mononucleosis in Children
Woong Young Moon, Sei Ho Oh, Tae Sung Ko, Young Seo Park, Hyung Nam Moon, Chang Yee Hong, Dae Won Kim
Clin Exp Pediatr. 1994;37(6):822-831.   Published online June 15, 1994
We reviewed th eclinical findings of infectious mononucleosis and performed Epstein-Barr virus (EBV) serologic antibody tests in infectious mononuleosis and healthy group. One group was 18 cases of children, diagnosed as infectious mononucleosis who had been admitted to the department of Pediatrics. Asan Medical Center for two years and eight months. From November, 1989 to June, 1992. Another group was...
Neurologic Complications after Open-Heart Surgery in Children
Tae Sung Ko, Ki Joong Kim, Dong Wook Kim, Yong Seung Hwang, Yong Jin Kim, Joon Ryang Rho
Clin Exp Pediatr. 1993;36(9):1245-1257.   Published online September 15, 1993
Neurologic complications after open-heart surgery are not only relatively common but also often fatal. In order to know the clinical characteristics and carsative risk factors, we carried out the retrospective study on 655 patients who had been admitted and undergone OHS at Seoul National University Children's Hospital during 2-year period from July 1990 to June 1992. The results...
The Effectf Zonisamide in Children with Refractory Epilepsies
Ki Joong Kim, Soo Ahn Chae, Tae Sung Ko, Dong Wook Kim, Yong Seung Hwang
Clin Exp Pediatr. 1993;36(8):1139-1145.   Published online August 15, 1993
Zonisamide was amministered to 20 patients with refractory epileptic seizures. The mean duration of the administration was 6 months, and the mean dosage was 7.2mg/kg/day. The efficacy of zonisamide was rated remarkable in 15% of the cases, improvement in 40%, and no change in 45%. The response rates of zonisamide were 62.5% for myoclonic seizures, 50% for tonic-clonic seizures, 80% for...
Hypercalciuria in Children with Hematuria.
Tae Sung Ko, Chang Youn Lee, Young Seo Park, Hae Il Cheong, Yong Choi, Kwang Wook Ko
Clin Exp Pediatr. 1989;32(5):644-652.   Published online May 31, 1989
Ten children with gross hematuria were diagnosed as hypercalciuria in the Department of Pediatrics, Seoul National University Children’s Hospital during the period from June 1983 to Aug. 1987. We reviewed their clinical data, retrospectively, and could obtain the following results. 1) The age at the onset of gross hematuria ranged from 4 months to 10 7/12 years, and the male to female ratio was...
Childhood Renal Diseases.
Tae Sung Ko, Hae Il Cheung, Yong Choi, Kwang Wook Ko
Clin Exp Pediatr. 1988;31(11):1468-1474.   Published online November 30, 1988
1978년 1월부터 1987년 12월까지 만 10년간 서울대학교 소아병원 소아과에 입원한 환자중 신질환 환아를 대상으로 후향적 인 임상통계학적 고찰을 시 행하여 다음과 같은 결과를 얻었다. 1) 10년기간중 신질환 환아는 총 2,023명으로 이는 동일기간 전체 소아과 입원환아(28,611)의 7.1 %에 해당하였고，전체 환아에 대한 신질환 환아의 비는 매년 거의 일정하였다. 2) 전체 신질환 환아의 남여 비 는 2.2 : 1이 었다. 3) 신증후군(38.8%), 요로감염(18.0%), 급성사구체신염(12.1%) 이 3대 질병을 이루었으며 다음 으로는 반복성 혈뇨(7.6%),...