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A case of imipramine induced toxicity with Brugada electrocardiographic pattern in a toddler

Woo-Yeon Choi, Soo-Min Park, Ui-Jeong Han, Young-Nam Kim, Young-Kuk Cho, Jae-Sook Ma

Clin Exp Pediatr. 2008;51(11):1232-1235. Published online November 15, 2008

Imipramine, a tricyclic antidepressant (TCA), is used for the treatment of non-polar depression and nocturnal enuresis in children in whom an organic pathology has been excluded, anxiety disorders, and neuropathic pain. Clinical toxicity following the treatment of TCAs, including imipramine, is well known. The anticholinergic effects initially present include a dry mouth, ileus, dilated pupils, urinary retention, and mild sinus...

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