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Original Article
Neurology
Long-term neurological cognitive, behavioral, functional, and quality of life outcomes after fetal myelomeningocele closure: a systematic review
Andre Marolop Pangihutan Siahaan, Martin Susanto, Sarma Nursani Lumbanraja, Dwi Herawati Ritonga
Clin Exp Pediatr. 2023;66(1):38-45.   Published online November 30, 2022
· Fetal myelomeningocele closure significantly improved long-term neurological cognitive, behavioral, functional, and quality of life outcomes, most likely by reducing hydrocephalus rates.
· However, fetal myelomeningocele closure is associated with a significant risk of pregnancy complications, especially premature rupture of membranes and preterm delivery.
Review Article
Systemic use of fluoroquinolone in children
Soo-Han Choi, Eun Young Kim, Yae-Jean Kim
Clin Exp Pediatr. 2013;56(5):196-201.   Published online May 28, 2013

Fluoroquinolones are an important class of antibiotics that are widely used in adult patients because of their broad spectrum of activity, good tissue penetration, and oral bioavailability. However, fluoroquinolone use in children is limited because juvenile animals developed arthropathy in previous experiments on fluoroquinolone use. Indications for fluoroquinolone use in patients younger than 18 years, as stated by the U.S....

Original Article
Responses and adverse effects of carboplatin-based chemotherapy for pediatric intracranial germ cell tumors
Suntae Ji, Hee Won Chueh, Ju Youn Kim, Su Jin Lim, Eun Joo Cho, Soo Hyun Lee, Keon Hee Yoo, Ki Woong Sung, Hong Hoe Koo
Clin Exp Pediatr. 2011;54(3):128-132.   Published online March 31, 2011
Purpose

Cisplatin-based chemotherapy has been commonly used for the treatment of intracranial germ cell tumors (IC-GCTs). However, this treatment exhibits some adverse effects such as renal problems and hearing difficulty. Carboplatin-based chemotherapy was administered to pediatric patients with IC-GCTs from August 2004 at the Samsung Medical Center. In this study, we assessed the responses and adverse effects of carboplatin-based chemotherapy in...

Ototoxicity in children receiving cisplatin chemotherapy
Hee Jin Jang, Hyung Rae Cho, Jae Hee Lee, Kun Yuk Bae, Jong Jin Seo, Hyung Nam Moon, Ho Joon Im
Clin Exp Pediatr. 2010;53(2):210-214.   Published online February 15, 2010
Purpose : Cisplatin is highly effective for the treatment of solid tumors in children. However, the clinical use of cisplatin is limited by its ototoxicity. The aim of this study was to evaluate the ototoxicity in children treated with cisplatin. Methods : We performed a single institution retrospective analysis of pediatric oncology patients who received cisplatin therapy between January 2001 and...
A study on the toilet training and influencing factors
Eun Ok Kim, Sang Hyun Yun, Young Taek Jang
Clin Exp Pediatr. 2009;52(7):778-784.   Published online July 15, 2009
Purpose : We aimed to determine the ideal age for initiating toilet training and investigate the factors influencing the training. Methods : The study population comprised 1,370 children aged 2-6 years, who visited the pediatric clinics in Jeonju, Iksan, and Gunsan. Their parents were given questionnaires in order to gather data about the types of diapers used, ages when toilet training...
The Safety and Immunogenicity of a Trivalent, Live, Attenuated MMR Vaccine, PriorixTM
Seung-In Ahn, Min-Kook Chung, Jung-Suk Yoo, Hye-Jeon Chung, Jae-Kyun Hur, Young-Kyu Shin, Jin-Keun Chang, Sung-Ho Cha
Clin Exp Pediatr. 2005;48(9):960-968.   Published online September 15, 2005
Purpose : This multi-center, open-label, clinical study was designed to evaluate the safety and immunogenicity of a trivalent, live, attenuated measles-mumps-rubella(MMR) vaccine, PriorixTM in Korean children. Methods : From July 2002 to February 2003, a total of 252 children, aged 12-15 months or 4-6 years, received PriorixTM at four centers : Han-il General Hospital, Kyunghee University Hospital, St. Paul's Hospital at...