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Original Article

Periperal Plasma Renin Activity in Children with Normotensive Reflux Nephropathy.

Chong Guk Lee, Kwang Mann Ko

Clin Exp Pediatr. 1988;31(6):731-737. Published online June 30, 1988

Peripheral renin activity was measured in 11 children with normotensive reflux nephropathy and 20 normal children to disclose the abnormality of the renin-angiotensin system in the patient group. 9 children among the patient group were allocated to single-dose captopril test for the assessment of the response to the test in patients with normotensive reflux nephropathy. 1. Contrary to the significant negative correlation between PRA and...

Captopril in Children with Renovacular Hypertension.

Yong Choi, Hoan Jong Lee, Hee Young Shin, Kwang Wook Ko, Chang Yee Hong

Clin Exp Pediatr. 1985;28(1):58-67. Published online January 31, 1985

Captopril, a kind of converting enzyme inhibitors, is a promising anti-hypertensive drug, which is developed recently, and studied mainly in adult patients. We administered captopril to 4 children with renovascular hypertension, three of them accompanied Takayasu's arteritis and the remainder had isolated lesion. Three to five times of initial trials were performed on each patient with 12.5 mg of captopril....

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