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Original Article

Histiocytic Medullary Reticulosis in Children: Report of Four Cases and Analysis of Previously Reported Cases.

Eue Cho Yang, Jae Ho Lee, Soon Ung Kang, Hyo Seop Ahn, Chang Yee Hong, Je G Chi, Yong Il Kim

Clin Exp Pediatr. 1981;24(10):928-941. Published online October 15, 1981

Histiocytic Medullary Reticulosis(H.M.R.) is a rapidly progressing fatal disease seen most often in adults, but it has been reported in children younger than 15 years of age. H.M.R. is clinically characterized by fever, wasting generalized lymphadenopathy and hepatosplenomegaly. In the terminal stage, jaundice, purpura, anemia and pancytopenia are all present with or without skin involvement. Cardinal pathologic features are systemized...

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