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Purpose : The incidence of Down syndrome, the most common chromosoaml anomaly, increases
with the advanced maternal age. Recently, however, the incidence of Down symdrome was
reported to have decreased with wide acceptance of prenatal diagnosis and planned parenthood,
prompting us to re-evaluate the incidence of Down syndrome in relation to changes in maternal
age.
Methods : Subjected to study were 296 Down cases: 26... |
