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Original Article

Allergy

Sex-based differences in factors associated with bronchial hyperresponsiveness in adolescents with childhood asthma

Young Hwan Kim, Yoon Young Jang, Jieun Jeong, Hai Lee Chung

Clin Exp Pediatr. 2021;64(5):229-238. Published online January 14, 2021

Web of Science 7 Crossref 7

Question: What factors are associated with bronchial hyperresponsiveness (BHR) in adolescents with childhood asthma?
Finding: Age, mold sensitization, and increased eosinophil count were associated with BHR in boys versus a reduced forced expiratory volume in 1 second/forced vital capacity ratio in girls. Early mold sensitization was a risk factor for persistent BHR in boys only.
Meaning: Sex-specific differences were observed in the factors associated with BHR in adolescents.

DOI: https://doi.org/10.3345/cep.2020.01585

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