Clinical and Experimental Pediatrics

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Original Article

Increased vascular endothelial growth factor in children with acute Mycoplasma pneumoniae pneumonia and wheezing

Young Seo, Byung Keun Yu, Yeon Joung Oh, Yoon Lee, Young Yoo, Ji Tae Choung, Young Yull Koh

Clin Exp Pediatr. 2008;51(5):487-491. Published online May 15, 2008

Purpose : Although Mycoplasma pneumoniae (M. pneumoniae) infection can cause wheezing in non-asthmatic children, the mechanisms of this symptom remain unclear. Vascular endothelial growth factor (VEGF) is a major mediator of angiogenesis and vascular permeability, and is also known to be elevated in cases of chronic pulmonary disease such as asthma. We hypothesized that VEGF may increase in children with...

A Clinical Study on Wheezing of Mycoplasma Pneumoniae Pneumonia in Children

Jeong Eun Kwon, Jun Ho Yoon, Jae Ook Lee, Im Ju Kang

Clin Exp Pediatr. 1993;36(10):1366-1374. Published online October 15, 1993

The relationship between respiratory infections and exacerbations of wheezing in patients with wheezy bronchitis or asthma has been described. Most respiratory infections were viral or Mycoplasma pneumoniae. This study was performed to evaluate the effect of Mycoplasma pneumoniae infection on bronchial reactivity and atopic background. 106 patients with Mycoplasma pneumoniae pneumonia who were admitted to the department of pediatrics, Fatima Hospital,...

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