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Review Article
Infection
Antibiotic pretreatment and culture yield in pediatric osteoarticular infection: a systematic review and meta-analysis
Mohamad Shieb, Caroline Decesare, Guyu Li, Elizabeth Ristagno
Clin Exp Pediatr. 2026;69(11):825-832.   Published online September 14, 2026
In this systematic review and meta-analysis of 9 studies comprising 1,704 tissue culture specimens from children with osteoarticular infection, antibiotic pretreatment was not associated with reduced tissue culture yield (odds ratio, 1.60; 95% confidence interval, 1.23–2.08). Empiric antibiotic therapy should not be withheld to preserve culture yield in suspected osteoarticular infection; invasive cultures should be obtained at the earliest safe opportunity without delaying treatment.
Original Article
Clinical Study of Acute Pyogenic Osteomyelitis in Children
Ji Sook Park, Jeong Suk Yeom, Sun Chul Hwang, Eun Sil Park, Ji Hyun Seo, Jae Young Lim, Chan Hoo Park, Hyang Ok Woo, Hee Shang Youn
Clin Exp Pediatr. 2005;48(7):731-736.   Published online July 15, 2005
Purpose : Acute pyogenic osteomyelitis is uncommon in children. Delayed diagnosis and inappropriate treatment are leading to growth failure and deformation. We review the clinical manifestations and treatment of acute osteomyelitis in children according to age. Methods : A retrospective analysis was made of 32 patients who underwent antibiotic management or operation between Aug 1989 and Dec 2003 for acute...
Etiologic Agents and Clinical Features of Acute Pyogenic Osteoarthritis in Children
Young Ho Kwak, Su Eun Park, Jung Youn Hong, He Sun Jung, Jin Young Park, Jung Hwan Choi, Hoan Jong Lee, In Ho Choi
Clin Exp Pediatr. 2000;43(4):506-513.   Published online April 15, 2000
Purpose : Though acute pyogenic infections of musculoskeletal system are infrequent in children, delayed diagnosis or inadequate management may cause serious chronic sequelae. We analysed 40 cases of children who were affected by acute septic osteomyelitis and/or septic arthritis to find etiologic agents and to establish proper initial antimicrobial therapy. Methods : Medical records of 40 cases of microbiologically confirmed acute...
Case Report
A Case of Chronic Recurrent Multifocal Osteomyelitis
Weon Young Lee, Eell Ryoo, Mi Jin Jeong, Kye Hwan Seol, Kil Hyen Kim, Hak Su Lee
Clin Exp Pediatr. 1996;39(5):732-737.   Published online May 15, 1996
Chronic recurrent multifocal osteomyelitis(CRMO) is an unusual inflammatory process involving multiple osseous sites. No causative agent can be consistently isolated from these lesions despite multiple biopsies and the affected child purses a clinical course of chronic remissions and exacerbations independent of antibiotic therapy. Biopsy of the lesions did not reveal any pathogens. Immunologic investigation revealed no abnormality common to the patient...
Original Article
A case of citrobacter freundii osteomyelitis.
Hyung Goo Cho, Dong Sig Kim, Hwang Min Kim, Jae Seung Yang, Baek Keun Lim, Jong Soo Kim
Clin Exp Pediatr. 1991;34(3):408-412.   Published online March 31, 1991
Citrobacter although once regarded as nonpathogenic, has been responsible for many well- documented pathologic conditions, especially in compromised hosts. These include urinary tract, pulmonary and bone infections, gastroenteritis, gangrenous ulcer with septicemia, meningitis, and brain abscess. Citrobacter organisms have a mosaic of 0, K and H antigens that are found in the Enterobacter- iaceae. Cross reactions with antisera of other members of the Enterobacteriaceae suggest...
Clinical observation of Osteomyelitis in Childhood.
Seong Gyoo Park, Young Suk Hong, Se Jin Kang, Sun Gyum Kim, Pyung Hwa Choi
Clin Exp Pediatr. 1990;33(4):499-505.   Published online April 30, 1990
After the discovery of penicillin by Fleming in 1939, the mortality rate in the acute stage of the childhood osteomyelitis was markedly decreased. But, because of abuse & misuse of the antibiotics and increment of resistant organisms to antibiotics, the incidence of complications, prevalance and chronic cases tended to increase. During the period of 12 years and 10 months extending from April, 1975 to...
Case Report
A Case of Tuberculous Osteomyelitis of the Mandible.
T H Son, H K Park, Y S Shin, M J Shin
Clin Exp Pediatr. 1983;26(1):71-75.   Published online January 31, 1983
The predilection sites of skeletal tuberculosis are mainly weight-bearing bones such as vertebrae, hip and knee joint. Involvement of non-weight bearing bones are rare. We experienced an unusual case of tuberculous osteomyelitis of the mandible in 3-year-5-month old female. The diagnosis was established by positive tuberculin skin test, roentgenographic findings and biopsy. Herein, a case of Tuberculous Osteomyelitis of Mandible was presented with...


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