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Original Article

Changes of PPD-Specific Immunoglobulin in Pulmonary Tuberculosis After Treatment.

Ja Young Kim, Mun Hwan Lee, Pyoung Han Hwang, Chan Uhng Joo, Jung Soo Kim

Clin Exp Pediatr. 1990;33(12):1647-1655. Published online December 31, 1990

The definite diagnosis and precise assessment of response to therapy is still a problem in childhood tuberculosis because these patients rarely produce sputum and if obtained it may be negative. For this reason, diagnosis rely largely on the clinical and X-ray examination, which have a low specificity and high proportion of false positive results. Recently immunologic diagnosis of tuberculosis using enzyme-linked immunosorbent assay (ELISA) was...

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