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Review Article
Nephrology (Genitourinary)
Obesity and chronic kidney disease: prevalence, mechanism, and management
Hyung Eun Yim, Kee Hwan Yoo
Clin Exp Pediatr. 2021;64(10):511-518.   Published online April 6, 2021
· Obesity is strongly associated with the development and progression of chronic kidney disease.
· Altered renal hemodynamics, metabolic effects, and lipid nephrotoxicity may play a key role in the development of obesity-related kidney disease.
· Children born to obese mothers are at increased risk of developing obesity and chronic kidney disease later in life.
· A multilevel approach is needed to prevent obesity and related chronic diseases.
Original Article
The impact of early detection through school urinary screening tests of membranoproliferative glomerulonephritis typeⅠ
Sung-Hoon Chung, Sung-Sin Park, Sung-Do Kim, Byoung-Soo Cho
Clin Exp Pediatr. 2007;50(11):1104-1109.   Published online November 15, 2007
Purpose : Since 1998, school urinary screening tests have been performed on Korean school children. We could detect and treat so many asymptomatic chronic renal disease in early stage. We investigated the efficacy of school urinary screening tests from children with membranoproliferative glomerulonephritis (MPGN) type I. Methods : We analyzed the characteristics and prognosis of 18 patients with MPGN type I...
Review Article
Evaluation of function and disorders of the adrenal gland in neonates
Il Tae Hwang
Clin Exp Pediatr. 2007;50(3):236-240.   Published online March 15, 2007
Majority of sick full term newborns have adequate adrenal cortical function in response to stress. Acutely ill neonates with a basal cortisol level less than 15 g/dL (414 nmol/L) suggest adrenal insufficiency and require function testing of adrenal function. In premature infant, immaturity of hypothalamic-pituitary adrenal axis (HPA axis), may limit the ability to increase cortisol production in response...
Original Article
A case of Addison's disease.
Cheol Hee Hwang, Dong Kui Lee, Myung Sug Nam, Mun Ki Cho
Clin Exp Pediatr. 1991;34(8):1169-1174.   Published online August 31, 1991
Addison’s disease is a rare disorder resulting from progressive adrenocortical destruction regardless of the nature of underlying process. A 5-year-old boy with Addison’s disease without other endocrine disorder presented with a brief review of the literature. The patient was admitted to out hospital because of poor appetite and generalized darkish brown pigmentation of skin and mucous membrane. On physical examination, skin and mucous membrane were...
A Case of Adrenoleukodystrophy.
Kee Sung Yang, Soo Tack Bae, Hong Bae Kim, Ji Sub Oh
Clin Exp Pediatr. 1989;32(3):430-437.   Published online March 31, 1989
We experienced a case of Adrenoleukodystrophy (ALD), which is a genetically determined metabolic disorder associated with progressive demyelination of brain white matter and adrenal insuficiency. An 11 year old male revealed rapidly evolving neuologic progression, decreased adrenal reserve, increased plasma content of very long chain fatty acids (VLCFAs) and typical radiological findings. We report here the clinical findings of this patient with brief review of...
A Case of Addison's Disease.
In Hoon Lee, H. D. Lee, Hee Ju Jeon, Chan Yung Kim
Clin Exp Pediatr. 1988;31(12):1689-1695.   Published online December 31, 1988
A 9-year-old girl with Addison’s disease without other endocrine disorder presented with a brief review of the literature. The patient was transferee! to our hospital because of darkish brown pigmentation of whole body and generalized weakness which had misunderstood cyanotic heart disease. On physical examination, she was poorly nourished and below 10 percentile in weight and height. Skin and mucous membrane were diffusely darkish brown,...