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Original Article
Clinical and Pathological Comparison of Neonatal Hepatitis and Extrahepatic Biliary Atresia in Korean Children
Jae Hong Park, Ju Suk Lee, Su Eun Park, Chang Hun Lee
Clin Exp Pediatr. 1998;41(10):1372-1379.   Published online October 15, 1998
Purpose : Neonatal hepatitis and congenital extrahepatic biliary atresia are two major causes of neonatal cholestasis. But the method of therapeutic trials used for each disease is essentially different. Nonetheless, it is very difficult to differentiate these diseases clinically and histologically. This study is aimed to find out major differences between the two by clinical characteristics and scoring of various...
The Usefulness of Measuring Serum α-fetoprotein and Thyroxine-binding Globulin to Differentiate between Neonatal Hepatitis and Congenital Extrahepatic Biliary Atresia
Soo Kyoung Lee, Ki Sup Chung
Clin Exp Pediatr. 1993;36(4):512-520.   Published online April 15, 1993
Together, neonatal hepatitis and biliary atresia make up approximately 70 to 80% of the causes of neonatal cholestasis. Biliary atresia must be differentiated from neonatal hepatitis as soon as possible in order to institute early surgical intervention. We performed this study to examine whether the measurement of the serum α-fetoprotein(AFP) and thyroxine-binding globulin(TBG) was useful for differentiating these two conditions....
Hepatic Rickets in Infancy with Neonatal Hepatitis
Mi Koo Kang, Eun Young Cho, Soo Jong Hong, Ki Soo Kim, Young Seo Park, Hyung Nam Moon, Chang Yee Hong
Clin Exp Pediatr. 1992;35(4):527-533.   Published online April 15, 1992
We had treated a hepatic rickets in 6 infants with neonatal hepatitis from June 1989 to August 1990 at Asan Medical Center. The results were as follows 1) Age of 6 patients were below 4 months and 4 patients were male, 2 patients were female. 2) The clinical findings were hepatosplenomegaly(5 cases), jaundice(4 cases), craniotabes (4 cases), failure to thrive(2 cases), hypocalcemiac seizure(2...
The Effect of Hepatitis B Vaccination on Newborns of Hepatitis B Carrier Mothers.
Ho Taek Kom, Pyung Kil Kim, Chang Ho Hong, Chul Lee
Clin Exp Pediatr. 1987;30(11):1228-1235.   Published online November 30, 1987
The transmission of hepatitis B virus (HBV) from carrier mothers to their infants is a serious problem in many countries and the transmission rate is reported to be as high as 60%. The best preventive method of perinatal transmission is hepatitis B immune globulin (HBIG) which confers a passive immunity and HB vaccine which confers an active immunity. However, the exact dosage and the...
Hepatobiliary Scintigraphy with 99mTc-DISIDA in the Evaluation of Neonatal Jaundice.
Kwang Soo Hwang, Sae Jin Lee, Kyung Sook Cho, Chong Dae Cho, Bok Hwan Park
Clin Exp Pediatr. 1984;27(7):664-672.   Published online July 31, 1984
Hepatobiliary scintigraphy with 99mTc-DISIDA was used to evaluate neonates with direct hyperbilirubinemia who were admitted to the department of Pediatrics, Maryknoll hospital, between May 1981 and Jun. 1983. 1)Total number of patients were 10, boys to girls ratio was 4:1, and age distribution ranging from 9 to 200 days of age. 2)Initial studies of the seven patients intrahepatic cholestasis showed definite...
Clinical Assessment of Extrahepatic Biliary Atresia and Neonatal Hepatitis.
Chong Ku Yun, Eue Cho Yang
Clin Exp Pediatr. 1984;27(1):33-42.   Published online January 31, 1984
A clinical assessment was carried out in 37 cases with Extrahepatic biliary atresia (EHBA) and 35 cases with Neonatal hepatitis (NH), who were admitted to the Dept, of Pediatrics and Pediatric Surgery, Seoul National University Hospital, during the 30 months from January 1980 to June 1982. The following results were obtained; 1)By sex distribution, 40% of EHBA and 69% of NH...
Etiological & Clinical Study for Neonatal Hepatitis & Biliary Atresia.
Ki Sub Chung, Kir Young Kim, Hyo Kyu Kim
Clin Exp Pediatr. 1983;26(5):440-448.   Published online May 31, 1983
The following result WBS obtained through the clinical observation of 67 cases with neonatal hepatitis, 7 cases with extrahepaticbiliary atresia, 1 case with intrahepatic biliary atresia admitted at Department of Pediatrics, Yonsei University Hospital during the period of January, 1979 through October, 1982. The clinical & etiological study was performed by the Hepatitis B marker, Liver function test, Liver scan, pathologic findings by percutaneous liver...
Case Report
A Case Of Choledochal Cyst In A Neonate.
Jong Man Lee, In Kyung Sung, Jong Seung Kim, Chang Kyu Oh
Clin Exp Pediatr. 1982;25(10):1068-1072.   Published online October 31, 1982
Congenital choledochal cyst is a rare disease, especially in fetal life and early infancy age. Our case was a 66 days old female baby who had the symptoms of jaundice, clay-colored stool, intermittent vomiting since birth and abdominal distension. Final diagnosis was choledochal cyst with neonatal hepatitis. An early accurate preoperative diagnosis has been associated with a marked decrease in the mortality. Roux-en-Y choledochocystojejunostomy was done. We...
A Case of Vertically Transmitted Neonatal Hepatitis B with Pancytopenia.
Young Chang Kim, Jae Oak Park
Clin Exp Pediatr. 1982;25(7):737-742.   Published online July 31, 1982
A newborn infant, who was low-birth weight(1,780gm), showed severe degree of jaundice on second day of life and skin color became dark greenish-yellow and moderate hepatosplenomegaly was noted on physical examination. Results of liver function test & radioimmuniassay for hepatitis B antigen of both infant and mother suggested that neonatal hepatitis B seemed to occure transplacentally during pregnancy from infected...