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Original Article

Diagnosis of Cytomegalovirus Infection in Neonatal and Infantile Periods Using Polymerase Chain Reaction

Young Ah Lee, Kyoung Lee, In Seong Jo, Woo Gap Chung

Clin Exp Pediatr. 1996;39(9):1271-1279. Published online September 15, 1996

Purpose : The aims of present study were to document the incidence of cytomegalovirus infection in neonatal and infantile periods especially in high-risk patients of associated infection by nested PCR of DNA from leukocytes and to evaluate the effectiveness of nested PCR in the diagnosis of congenital cytomegalovirus infection. Methods : Genomic DNA was extracted from peripheral leukocytes of 204 neonates and infants during the...

Congenital Cytomegalovirus infection.

Kang Woo park, Ho Seek Ahn, Eui Bon Koo, Sung Won Kim, Kil Hyun Kim

Clin Exp Pediatr. 1990;33(9):1271-1275. Published online September 30, 1990

We report a case of congenital cytomegalovirus infection that was associated with microcephaly, hydrocephalus and periventricular calcification. The male baby was born after 39wks gestation to 28 year-old mother who had no prenatel problem except for active pulmonary tuberculosis and pre- mature rupture of membrain. Hydrocephalus was recognized by antenatal ultrasonography at 8 weeks of geststional age and microcephaly was noted at birth. This enable...

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