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Original Article

A case of cystic fibrosis presented with meconium ileus in a female neonate

In-Ok Hwang, Eun-Sil Lee

Clin Exp Pediatr. 2007;50(12):1252-1256. Published online December 15, 2007

Meconium ileus (MI) is the earliest clinical manifestation of cystic fibrosis (CF) in infants. It arises from the intraluminal accumulation of highly viscid, protein-rich meconium, typically present in the terminal ileum as a neonatal intestinal obstruction. Therefore, the clinical symptoms include abdominal distension, bilious vomiting and delayed passage of meconium. CF is caused by mutations in the transmembrane conductance regulator...

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