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Original Article

The effect of pertussis vaccine on streptozotocin induced diabetic rats.

Kyung Rae Moon, Kwang Rhun Koo, Sang Kee Park, Yeong Bong Park, Byoung Rai Lee, Keun Hong Kee

Clin Exp Pediatr. 1991;34(7):897-906. Published online July 31, 1991

Streptozotocin produces diabetes in laboratory animals through the destuction of the pancreatic beta cells. The diabetogenic activity of STZ, however, is known to be modified by several agents such as nicotinamide, diazoxide, adrenergic blockers and petussis vaccine (PV). The present study was undertaken to observe the protective effect of PV or boiled pertussis vaccine (bPV; incubating the PV at 80 C for 30 mintues)...

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